MX362058B - Péptido pntx(19) sintético, composición farmacéutica y uso. - Google Patents

Péptido pntx(19) sintético, composición farmacéutica y uso.

Info

Publication number
MX362058B
MX362058B MX2015002279A MX2015002279A MX362058B MX 362058 B MX362058 B MX 362058B MX 2015002279 A MX2015002279 A MX 2015002279A MX 2015002279 A MX2015002279 A MX 2015002279A MX 362058 B MX362058 B MX 362058B
Authority
MX
Mexico
Prior art keywords
peptide
pntx
pharmaceutical compositions
synthetic
relates
Prior art date
Application number
MX2015002279A
Other languages
English (en)
Other versions
MX2015002279A (es
Inventor
Elena De Lima Perez Garcia Maria
Nunes Da Silva Carolina
De Marco Almeida Flávia
Da Silva Lomeo Rosangela
Sérgio Lacerda Beirao Paulo
Silva Torres Fernanda
Monteiro De Castro Pimenta Adriano
Original Assignee
Univ Federal De Minas Gerais Ufmg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BR102012020800A external-priority patent/BR102012020800A2/pt
Priority claimed from BR102013020574-5A external-priority patent/BR102013020574B1/pt
Application filed by Univ Federal De Minas Gerais Ufmg filed Critical Univ Federal De Minas Gerais Ufmg
Publication of MX2015002279A publication Critical patent/MX2015002279A/es
Publication of MX362058B publication Critical patent/MX362058B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Insects & Arthropods (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a un péptido sintético que tiene 19 aminoácidos, llamado PnTx(19) formado de la secuencia de la toxica PnTx2-6 de la araña Phoneutría nigriventer. La invención también se refiere a composiciones farmacéuticas que contienen este péptido y a su uso para el tratamiento de la disfunción eréctil y/o para potencializar la función eréctil.
MX2015002279A 2012-08-20 2013-08-20 Péptido pntx(19) sintético, composición farmacéutica y uso. MX362058B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BR102012020800A BR102012020800A2 (pt) 2012-08-20 2012-08-20 Peptídeo sintético pntx (19), composições farmacêuticas e uso
BR102013020574-5A BR102013020574B1 (pt) 2013-08-13 2013-08-13 PEPTÍDEO SINTÉTICO PnTx(19), COMPOSIÇÕES FARMACÊUTICAS E USO
PCT/BR2013/000319 WO2014028997A1 (pt) 2012-08-20 2013-08-20 Peptídeo sintético pntx(19), composições farmacêuticas e uso

Publications (2)

Publication Number Publication Date
MX2015002279A MX2015002279A (es) 2015-10-15
MX362058B true MX362058B (es) 2019-01-07

Family

ID=50149301

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015002279A MX362058B (es) 2012-08-20 2013-08-20 Péptido pntx(19) sintético, composición farmacéutica y uso.

Country Status (8)

Country Link
US (1) US9279004B2 (es)
EP (1) EP2899198B1 (es)
JP (1) JP6430938B2 (es)
KR (1) KR102103715B1 (es)
CL (1) CL2015000415A1 (es)
MX (1) MX362058B (es)
PT (1) PT2899198T (es)
WO (1) WO2014028997A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101613302B1 (ko) * 2015-12-30 2016-04-18 (주)넥스젠바이오텍 Sv82 폴리펩타이드 및 이를 유효성분으로 함유하는 피부 주름 개선 및 탄력 유지용 화장료 조성물
KR101636851B1 (ko) * 2016-06-03 2016-07-06 (주)넥스젠바이오텍 피부 세포 증식 효과가 증가한 열 안정성 인간 상피세포성장인자-거미독 융합단백질 및 이를 유효성분으로 함유하는 피부 주름 개선 및 탄력 유지용 화장료 조성물
US10905738B2 (en) * 2018-07-05 2021-02-02 Biozeus Desenvolvimento De Produtos Biofarmacêuticos Synthetic peptides, prodrugs, pharmaceutical compositions and uses
WO2021042193A1 (en) * 2019-09-03 2021-03-11 Biozeus Desenvolvimento De Produtos Biofarmacêuticos Method and use of pnpp-19 for preventing and treating eye diseases
US20240317806A1 (en) * 2023-02-17 2024-09-26 Biozeus Biopharmaceuticals S.A. Topical peptide formulation for the treatment of sexual dysfunction

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2007003884A1 (es) * 2007-12-31 2009-09-25 Laboratorios Andromaco S A Péptido derivado del veneno de la araña viuda negra, procedimiento para preparar dicho péptido, composición farmacéutica que lo comprende, y uso de dicha composición para la preparación de un medicamente útil para el tratamiento de la disfunción sexual.
BRPI0800596A2 (pt) * 2008-01-31 2009-09-22 Univ Minas Gerais método para a potencialização da função erétil através do uso das composições farmacêuticas de toxina tx2-6 da aranha phoneutria nigriventer

Also Published As

Publication number Publication date
EP2899198A4 (en) 2016-01-20
PT2899198T (pt) 2018-06-29
KR20150084766A (ko) 2015-07-22
WO2014028997A1 (pt) 2014-02-27
US9279004B2 (en) 2016-03-08
JP6430938B2 (ja) 2018-11-28
US20150218233A1 (en) 2015-08-06
EP2899198A1 (en) 2015-07-29
CL2015000415A1 (es) 2015-09-11
EP2899198B1 (en) 2018-05-02
KR102103715B1 (ko) 2020-04-23
JP2015535808A (ja) 2015-12-17
MX2015002279A (es) 2015-10-15

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