MX361681B - Composiciones de proteína estabilizadas basadas en alcanos semifluorados. - Google Patents
Composiciones de proteína estabilizadas basadas en alcanos semifluorados.Info
- Publication number
- MX361681B MX361681B MX2014008929A MX2014008929A MX361681B MX 361681 B MX361681 B MX 361681B MX 2014008929 A MX2014008929 A MX 2014008929A MX 2014008929 A MX2014008929 A MX 2014008929A MX 361681 B MX361681 B MX 361681B
- Authority
- MX
- Mexico
- Prior art keywords
- semifluorinated alkanes
- compositions based
- protein compositions
- compositions
- stabilised protein
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 150000001335 aliphatic alkanes Chemical class 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 230000002776 aggregation Effects 0.000 abstract 1
- 238000004220 aggregation Methods 0.000 abstract 1
- 230000000975 bioactive effect Effects 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000007918 intramuscular administration Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000007920 subcutaneous administration Methods 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
- A61K38/385—Serum albumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21001—Chymotrypsin (3.4.21.1)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12152159 | 2012-01-23 | ||
| PCT/EP2013/051163 WO2013110621A1 (en) | 2012-01-23 | 2013-01-22 | Stabilised protein compositions based on semifluorinated alkanes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014008929A MX2014008929A (es) | 2015-06-02 |
| MX361681B true MX361681B (es) | 2018-12-13 |
Family
ID=47598843
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014008929A MX361681B (es) | 2012-01-23 | 2013-01-22 | Composiciones de proteína estabilizadas basadas en alcanos semifluorados. |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US9757460B2 (OSRAM) |
| EP (1) | EP2806886B1 (OSRAM) |
| JP (1) | JP6084987B2 (OSRAM) |
| KR (1) | KR101989648B1 (OSRAM) |
| CN (1) | CN104066442B (OSRAM) |
| AU (1) | AU2013211645B2 (OSRAM) |
| BR (1) | BR112014017719A8 (OSRAM) |
| CA (1) | CA2862974C (OSRAM) |
| DK (1) | DK2806886T3 (OSRAM) |
| ES (1) | ES2625538T3 (OSRAM) |
| MX (1) | MX361681B (OSRAM) |
| PL (1) | PL2806886T3 (OSRAM) |
| PT (1) | PT2806886T (OSRAM) |
| WO (1) | WO2013110621A1 (OSRAM) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2564502T3 (es) | 2010-03-17 | 2016-03-23 | Novaliq Gmbh | Composición farmacéutica para el tratamiento de la presión intraocular aumentada |
| EP2444063A1 (en) | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
| EP2462921A1 (en) | 2010-11-11 | 2012-06-13 | Novaliq GmbH | Liquid pharmaceutical compositions for the treatment of a posterior eye disease |
| CN103561724B (zh) | 2011-05-25 | 2016-06-29 | 诺瓦利克有限责任公司 | 给药给甲的药物组合物 |
| PL2714010T3 (pl) | 2011-05-25 | 2017-08-31 | Novaliq Gmbh | Kompozycja farmaceutyczna do miejscowego stosowania oparta na semifluorowanych alkanach |
| MX361681B (es) | 2012-01-23 | 2018-12-13 | Novaliq Gmbh | Composiciones de proteína estabilizadas basadas en alcanos semifluorados. |
| CN113679699B (zh) | 2012-09-12 | 2022-10-28 | 诺瓦利克有限责任公司 | 包含半氟化烷烃的混合物的组合物 |
| WO2014041071A1 (en) | 2012-09-12 | 2014-03-20 | Novaliq Gmbh | Semifluorinated alkane compositions |
| DK3024484T3 (en) | 2013-07-23 | 2018-10-08 | Novaliq Gmbh | STABILIZED ANTIBODY COMPOSITIONS |
| CN112641720A (zh) | 2014-03-03 | 2021-04-13 | 诺华股份有限公司 | 硫辛酸胆碱酯组合物及使用方法 |
| CN110403923B (zh) | 2015-09-30 | 2021-09-21 | 诺瓦利克有限责任公司 | 半氟化化合物和其组合物 |
| KR102584063B1 (ko) | 2015-09-30 | 2023-09-27 | 노바리크 게엠베하 | 부분불소화 화합물 |
| KR102257916B1 (ko) | 2016-06-23 | 2021-05-28 | 노바리크 게엠베하 | 드롭 디스펜서를 포함하는 키트 |
| MX2019003363A (es) | 2016-09-22 | 2019-10-02 | Novaliq Gmbh | Composiciones farmaceuticas para usarse en la terapia de la blefaritis. |
| ES2965677T3 (es) | 2016-09-23 | 2024-04-16 | Novaliq Gmbh | Composiciones oftálmicas que comprenden ciclosporina |
| EP3399962B1 (en) | 2016-12-23 | 2020-06-10 | Novaliq GmbH | Ophthalmic composition for treatment of dry eye disease |
| AU2018253944B2 (en) | 2017-04-21 | 2022-09-15 | Dermaliq Therapeutics, Inc. | Iodine compositions |
| WO2018202835A1 (en) | 2017-05-05 | 2018-11-08 | Novaliq Gmbh | Process for the production of semifluorinated alkanes |
| EP3621601A1 (en) | 2017-05-12 | 2020-03-18 | Novaliq GmbH | Pharmaceutical compositions comprosing semifluorinated alkanes for the treatment of contact lense-related conditions |
| MX2020003534A (es) | 2017-09-27 | 2020-07-29 | Novaliq Gmbh | Composiciones oftalmicas que comprenden latanoprost para usarse en el tratamiento de las enfermedades oculares. |
| CN111182893A (zh) | 2017-10-04 | 2020-05-19 | 诺瓦利克有限责任公司 | 包含f6h8的眼用组合物 |
| BR112020017838A2 (pt) | 2018-03-02 | 2020-12-22 | Novaliq Gmbh | Composições farmacêuticas que compreendem nebivolol |
| JP2021522219A (ja) | 2018-04-27 | 2021-08-30 | ノバリック ゲーエムベーハー | 緑内障の治療のためのタフルプロストを含む眼科用組成物 |
| EP3856128B1 (en) | 2018-09-27 | 2023-06-07 | Dermaliq Therapeutics, Inc. | Topical sunscreen formulation |
| WO2020064549A1 (en) | 2018-09-27 | 2020-04-02 | Novaliq Gmbh | Lipid barrier repair |
| EP4406533A3 (en) | 2018-10-12 | 2024-10-09 | Novaliq GmbH | Ophthalmic composition for treatment of dry eye disease |
| US12397039B2 (en) | 2019-02-13 | 2025-08-26 | Novaliq Gmbh | Compositions and methods for the treatment of ocular neovascularization |
| EP4025235A1 (en) | 2019-09-06 | 2022-07-13 | Novaliq GmbH | Ophthalmic composition for the treatment of uveitis |
| JP7761562B2 (ja) * | 2019-11-27 | 2025-10-28 | ノバリック ゲーエムベーハー | 非水性溶媒で懸濁されたタンパク質粒子を含む懸濁製剤 |
| CN115487305A (zh) * | 2022-09-21 | 2022-12-20 | 江苏君隽生物科技有限公司 | 一种用于递送活性药物成分的液体组合物 |
| WO2025133214A1 (en) | 2023-12-21 | 2025-06-26 | Novaliq Gmbh | Ophthalmic polypeptide compositions for the treatment of posterior eye disorders |
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| ES2564502T3 (es) | 2010-03-17 | 2016-03-23 | Novaliq Gmbh | Composición farmacéutica para el tratamiento de la presión intraocular aumentada |
| DE102010022567A1 (de) | 2010-06-02 | 2011-12-08 | Fluoron Gmbh | Zubereitung |
| EP2444063A1 (en) | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
| EP2462921A1 (en) | 2010-11-11 | 2012-06-13 | Novaliq GmbH | Liquid pharmaceutical compositions for the treatment of a posterior eye disease |
| TR201901309T4 (tr) | 2011-01-04 | 2019-02-21 | Novaliq Gmbh | Semiflorlanmış alkanları içeren o/w emülsiyonları. |
| CN103561724B (zh) | 2011-05-25 | 2016-06-29 | 诺瓦利克有限责任公司 | 给药给甲的药物组合物 |
| PL2714010T3 (pl) | 2011-05-25 | 2017-08-31 | Novaliq Gmbh | Kompozycja farmaceutyczna do miejscowego stosowania oparta na semifluorowanych alkanach |
| MX361681B (es) | 2012-01-23 | 2018-12-13 | Novaliq Gmbh | Composiciones de proteína estabilizadas basadas en alcanos semifluorados. |
| WO2014041071A1 (en) | 2012-09-12 | 2014-03-20 | Novaliq Gmbh | Semifluorinated alkane compositions |
| CN113679699B (zh) | 2012-09-12 | 2022-10-28 | 诺瓦利克有限责任公司 | 包含半氟化烷烃的混合物的组合物 |
| EP2783703A1 (en) | 2013-03-25 | 2014-10-01 | B. Braun Melsungen AG | Semifluorocarbon compound containing contrast agent |
| DK3024484T3 (en) | 2013-07-23 | 2018-10-08 | Novaliq Gmbh | STABILIZED ANTIBODY COMPOSITIONS |
| EP2944324A1 (de) | 2014-05-13 | 2015-11-18 | LTS LOHMANN Therapie-Systeme AG | Verwendung von semifluorierten Alkanen in transdermalen therapeutischen Systemen |
| CN110403923B (zh) | 2015-09-30 | 2021-09-21 | 诺瓦利克有限责任公司 | 半氟化化合物和其组合物 |
| KR102584063B1 (ko) | 2015-09-30 | 2023-09-27 | 노바리크 게엠베하 | 부분불소화 화합물 |
-
2013
- 2013-01-22 MX MX2014008929A patent/MX361681B/es active IP Right Grant
- 2013-01-22 ES ES13700911.4T patent/ES2625538T3/es active Active
- 2013-01-22 PT PT137009114T patent/PT2806886T/pt unknown
- 2013-01-22 WO PCT/EP2013/051163 patent/WO2013110621A1/en not_active Ceased
- 2013-01-22 CA CA2862974A patent/CA2862974C/en active Active
- 2013-01-22 US US14/373,877 patent/US9757460B2/en not_active Ceased
- 2013-01-22 JP JP2014552660A patent/JP6084987B2/ja active Active
- 2013-01-22 DK DK13700911.4T patent/DK2806886T3/en active
- 2013-01-22 KR KR1020147019633A patent/KR101989648B1/ko active Active
- 2013-01-22 BR BR112014017719A patent/BR112014017719A8/pt not_active Application Discontinuation
- 2013-01-22 EP EP13700911.4A patent/EP2806886B1/en active Active
- 2013-01-22 CN CN201380006417.2A patent/CN104066442B/zh active Active
- 2013-01-22 AU AU2013211645A patent/AU2013211645B2/en active Active
- 2013-01-22 PL PL13700911T patent/PL2806886T3/pl unknown
- 2013-06-22 US US17/155,058 patent/USRE49758E1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9757460B2 (en) | 2017-09-12 |
| DK2806886T3 (en) | 2017-06-06 |
| KR20140125353A (ko) | 2014-10-28 |
| MX2014008929A (es) | 2015-06-02 |
| CA2862974A1 (en) | 2013-08-01 |
| CN104066442B (zh) | 2018-05-18 |
| BR112014017719A2 (OSRAM) | 2017-06-20 |
| PT2806886T (pt) | 2017-03-24 |
| CN104066442A (zh) | 2014-09-24 |
| AU2013211645B2 (en) | 2017-06-15 |
| US20140369993A1 (en) | 2014-12-18 |
| KR101989648B1 (ko) | 2019-06-14 |
| JP6084987B2 (ja) | 2017-02-22 |
| EP2806886A1 (en) | 2014-12-03 |
| EP2806886B1 (en) | 2017-03-01 |
| JP2015504082A (ja) | 2015-02-05 |
| ES2625538T3 (es) | 2017-07-19 |
| USRE49758E1 (en) | 2023-12-19 |
| CA2862974C (en) | 2021-11-16 |
| PL2806886T3 (pl) | 2017-08-31 |
| WO2013110621A1 (en) | 2013-08-01 |
| AU2013211645A1 (en) | 2014-07-17 |
| BR112014017719A8 (pt) | 2017-07-11 |
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