MX361136B - Compuestos quimicos. - Google Patents

Compuestos quimicos.

Info

Publication number
MX361136B
MX361136B MX2015009465A MX2015009465A MX361136B MX 361136 B MX361136 B MX 361136B MX 2015009465 A MX2015009465 A MX 2015009465A MX 2015009465 A MX2015009465 A MX 2015009465A MX 361136 B MX361136 B MX 361136B
Authority
MX
Mexico
Prior art keywords
chemical compounds
formula
pharmaceutically
processes
preparation
Prior art date
Application number
MX2015009465A
Other languages
English (en)
Other versions
MX2015009465A (es
Inventor
Peter Tomkinson Gary
Christophe Barlaam Bernard
Berry David
Delouvrie Benedicte
Steven Harris Craig
Marie Paul Lambert-Van Der Brempt Christine
Ouvry Gilles
Patrick Reid Gary
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MX2015009465A publication Critical patent/MX2015009465A/es
Publication of MX361136B publication Critical patent/MX361136B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Abstract

La invención se relaciona con compuestos de Fórmula (I), o sales farmacéuticamente aceptables de los mismos, en donde R1 y R2 tienen cualquiera de los significados definidos anteriormente en la presente en la descripción; procesos para su preparación, composiciones farmacéuticas que los contienen y su uso en el tratamiento de trastornos proliferativos celulares. (ver Fórmula).
MX2015009465A 2013-01-23 2014-01-22 Compuestos quimicos. MX361136B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13305078 2013-01-23
PCT/GB2014/050163 WO2014114928A1 (en) 2013-01-23 2014-01-22 Chemical compounds

Publications (2)

Publication Number Publication Date
MX2015009465A MX2015009465A (es) 2015-09-28
MX361136B true MX361136B (es) 2018-11-28

Family

ID=47623992

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015009465A MX361136B (es) 2013-01-23 2014-01-22 Compuestos quimicos.

Country Status (27)

Country Link
US (2) US9156831B2 (es)
EP (1) EP2948447B1 (es)
JP (1) JP6307096B2 (es)
KR (1) KR102202516B1 (es)
CN (1) CN104936953B (es)
AP (1) AP2015008604A0 (es)
AR (1) AR094553A1 (es)
AU (1) AU2014208964B2 (es)
BR (1) BR112015017331B1 (es)
CA (1) CA2897279C (es)
CL (1) CL2015002027A1 (es)
CR (1) CR20150367A (es)
DO (1) DOP2015000170A (es)
ES (1) ES2608395T3 (es)
HK (1) HK1214592A1 (es)
IL (1) IL239890A0 (es)
MA (1) MA38287B1 (es)
MX (1) MX361136B (es)
NI (1) NI201500096A (es)
PE (1) PE20151979A1 (es)
PH (1) PH12015501584A1 (es)
RU (1) RU2644769C2 (es)
SG (1) SG11201505631PA (es)
TN (1) TN2015000313A1 (es)
TW (1) TWI606047B (es)
UY (1) UY35275A (es)
WO (1) WO2014114928A1 (es)

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TW201825465A (zh) 2016-09-23 2018-07-16 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
TW201813963A (zh) 2016-09-23 2018-04-16 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
TW201815787A (zh) 2016-09-23 2018-05-01 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
CN107137405A (zh) * 2017-04-14 2017-09-08 黄德莲 一种治疗肾炎的药物组合物
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US20220033775A1 (en) 2018-11-05 2022-02-03 Iovance Biotherapeutics, Inc. Expansion of tils utilizing akt pathways inhibitors
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US20220167618A1 (en) 2019-03-08 2022-06-02 Syngenta Crop Protection Ag Pesticidally active azole-amide compounds
WO2020188014A1 (en) 2019-03-20 2020-09-24 Syngenta Crop Protection Ag Pesticidally active azole amide compounds
WO2020193341A1 (en) 2019-03-22 2020-10-01 Syngenta Crop Protection Ag N-[1-(5-bromo-2-pyrimidin-2-yl-1,2,4-triazol-3-yl)ethyl]-2-cyclopropyl-6-(trifluoromethyl)pyridine-4-carboxamide derivatives and related compounds as insecticides
CN115443128A (zh) 2020-04-24 2022-12-06 阿斯利康(瑞典)有限公司 药物配制品

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Also Published As

Publication number Publication date
PH12015501584A1 (en) 2015-10-05
ES2608395T3 (es) 2017-04-10
DOP2015000170A (es) 2015-08-16
PE20151979A1 (es) 2016-01-15
CN104936953A (zh) 2015-09-23
AU2014208964B2 (en) 2016-09-01
BR112015017331B1 (pt) 2022-01-11
UY35275A (es) 2014-07-31
HK1214592A1 (zh) 2016-07-29
MA38287A1 (fr) 2018-01-31
CA2897279C (en) 2020-12-29
RU2644769C2 (ru) 2018-02-14
RU2015132370A (ru) 2017-03-02
NI201500096A (es) 2016-02-16
TN2015000313A1 (en) 2017-01-03
EP2948447B1 (en) 2016-09-21
MX2015009465A (es) 2015-09-28
TWI606047B (zh) 2017-11-21
BR112015017331A8 (pt) 2019-11-12
US9156831B2 (en) 2015-10-13
US20160137634A1 (en) 2016-05-19
CN104936953B (zh) 2017-03-08
US9657008B2 (en) 2017-05-23
KR102202516B1 (ko) 2021-01-12
CL2015002027A1 (es) 2015-11-13
MA38287B1 (fr) 2018-08-31
WO2014114928A1 (en) 2014-07-31
SG11201505631PA (en) 2015-08-28
JP2016508484A (ja) 2016-03-22
AR094553A1 (es) 2015-08-12
BR112015017331A2 (pt) 2017-07-11
CR20150367A (es) 2015-10-20
US20140206700A1 (en) 2014-07-24
AP2015008604A0 (en) 2015-07-31
TW201522329A (zh) 2015-06-16
AU2014208964A1 (en) 2015-08-06
KR20150109385A (ko) 2015-10-01
EP2948447A1 (en) 2015-12-02
CA2897279A1 (en) 2014-07-31
JP6307096B2 (ja) 2018-04-04
IL239890A0 (en) 2015-08-31

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