MX360411B - Uso de tiosulfato para potenciar el efecto anti-patogenico de los lactobacilos. - Google Patents

Uso de tiosulfato para potenciar el efecto anti-patogenico de los lactobacilos.

Info

Publication number
MX360411B
MX360411B MX2015000335A MX2015000335A MX360411B MX 360411 B MX360411 B MX 360411B MX 2015000335 A MX2015000335 A MX 2015000335A MX 2015000335 A MX2015000335 A MX 2015000335A MX 360411 B MX360411 B MX 360411B
Authority
MX
Mexico
Prior art keywords
thiosulphate
lactobacillus
potentiate
order
pathogen effect
Prior art date
Application number
MX2015000335A
Other languages
English (en)
Other versions
MX2015000335A (es
Inventor
Adrien Nivoliez
Original Assignee
Probionov
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Probionov filed Critical Probionov
Publication of MX2015000335A publication Critical patent/MX2015000335A/es
Publication of MX360411B publication Critical patent/MX360411B/es

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)

Abstract

La presente invención se refiere al uso de tiosulfato para potenciar el efecto anti-patogénico de bacterias lactobacilos; el tiosulfato se encuentra en una cantidad de por lo menos 100 mg para 107 a 1010 unidades formadoras de colonias de lactobacilos; la invención se refiere también a una composición farmacéutica que incluye por lo menos 100 mg de tiosulfato por gramo, en combinación con una cepa Lactobacillus crispatus y a su uso en el tratamiento de infecciones urogenitales tales como vaginosis, candidiasis e infecciones del tracto urinario.
MX2015000335A 2012-07-09 2013-07-09 Uso de tiosulfato para potenciar el efecto anti-patogenico de los lactobacilos. MX360411B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1256570A FR2992861B1 (fr) 2012-07-09 2012-07-09 Utilisation de thiosulfate pour potentialiser l'effet anti-pathogene des lactobacilles
PCT/EP2013/064451 WO2014009349A1 (fr) 2012-07-09 2013-07-09 Utilisation de thiosulfate pour potentialiser l'effet anti-pathogene des lactobacilles

Publications (2)

Publication Number Publication Date
MX2015000335A MX2015000335A (es) 2015-07-14
MX360411B true MX360411B (es) 2018-10-30

Family

ID=46826800

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015000335A MX360411B (es) 2012-07-09 2013-07-09 Uso de tiosulfato para potenciar el efecto anti-patogenico de los lactobacilos.

Country Status (16)

Country Link
US (3) US20150139969A1 (es)
EP (1) EP2869825B1 (es)
KR (1) KR101972198B1 (es)
CN (2) CN112999240A (es)
AU (1) AU2013289241A1 (es)
BR (1) BR112014033013A2 (es)
CA (1) CA2877666C (es)
ES (1) ES2604880T3 (es)
FR (1) FR2992861B1 (es)
IN (1) IN2014DN11238A (es)
MX (1) MX360411B (es)
PL (1) PL2869825T3 (es)
RU (1) RU2667122C2 (es)
SA (1) SA113340702B1 (es)
TW (1) TW201414481A (es)
WO (1) WO2014009349A1 (es)

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CN113564075A (zh) * 2015-06-29 2021-10-29 辉凌制药公司 用于治疗例如细菌性阴道病的鼠李糖乳杆菌细菌
LU92820B1 (fr) * 2015-09-08 2017-03-20 Vesale Pharma International Sa Composition comprenant au moins une bactérie probiotique et destinée à être utilisée pour le traitement de mycoses buccales
FR3048361B1 (fr) * 2016-03-01 2020-12-18 Biose Compositions pour le traitement des candidoses
CN110799198A (zh) * 2016-11-30 2020-02-14 普罗生物瑞士股份公司 用于稳定阴道液的酸度和氧化还原状态的基于合适的生化组合物的泌尿生殖器医疗设备制剂
CN112020359A (zh) 2018-02-09 2020-12-01 分贝治疗公司 含有抗铂化学保护剂的高渗药物组合物
US10813947B1 (en) 2019-05-31 2020-10-27 Decibel Therapeutics, Inc. Methods of otoprotection against platinum-based antineoplastic agents

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WO2000035465A2 (en) 1998-12-11 2000-06-22 Urex Biotech Inc. Oral administration of lactobacillus for the treatment and prevention of urogenital infection
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US6653062B1 (en) * 2000-07-26 2003-11-25 Wisconsin Alumni Research Foundation Preservation and storage medium for biological materials
DE60229169D1 (de) * 2002-03-13 2008-11-13 Matsushita Electric Ind Co Ltd Kühlvorrichtung
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US7479481B2 (en) * 2004-05-06 2009-01-20 Molichem Medicines, Inc. Treatment of ocular diseases and disorders using lantibiotic compositions
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Also Published As

Publication number Publication date
ES2604880T3 (es) 2017-03-09
BR112014033013A2 (pt) 2017-06-27
US20150139969A1 (en) 2015-05-21
KR20150029737A (ko) 2015-03-18
SA113340702B1 (ar) 2015-10-14
US11202799B2 (en) 2021-12-21
TW201414481A (zh) 2014-04-16
FR2992861B1 (fr) 2014-10-17
CA2877666C (fr) 2020-07-14
RU2667122C2 (ru) 2018-09-14
CA2877666A1 (fr) 2014-01-16
MX2015000335A (es) 2015-07-14
US20180360874A1 (en) 2018-12-20
US20220062330A1 (en) 2022-03-03
KR101972198B1 (ko) 2019-04-24
EP2869825B1 (fr) 2016-08-24
CN112999240A (zh) 2021-06-22
CN104519892A (zh) 2015-04-15
FR2992861A1 (fr) 2014-01-10
AU2013289241A1 (en) 2015-01-29
IN2014DN11238A (es) 2015-10-02
EP2869825A1 (fr) 2015-05-13
WO2014009349A1 (fr) 2014-01-16
PL2869825T3 (pl) 2017-04-28
RU2015103115A (ru) 2016-08-27

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