MX360411B - Uso de tiosulfato para potenciar el efecto anti-patogenico de los lactobacilos. - Google Patents
Uso de tiosulfato para potenciar el efecto anti-patogenico de los lactobacilos.Info
- Publication number
- MX360411B MX360411B MX2015000335A MX2015000335A MX360411B MX 360411 B MX360411 B MX 360411B MX 2015000335 A MX2015000335 A MX 2015000335A MX 2015000335 A MX2015000335 A MX 2015000335A MX 360411 B MX360411 B MX 360411B
- Authority
- MX
- Mexico
- Prior art keywords
- thiosulphate
- lactobacillus
- potentiate
- order
- pathogen effect
- Prior art date
Links
- DHCDFWKWKRSZHF-UHFFFAOYSA-L thiosulfate(2-) Chemical compound [O-]S([S-])(=O)=O DHCDFWKWKRSZHF-UHFFFAOYSA-L 0.000 title abstract 4
- 241000186660 Lactobacillus Species 0.000 title abstract 3
- 230000002223 anti-pathogen Effects 0.000 title abstract 2
- 230000000694 effects Effects 0.000 title abstract 2
- 229940039696 lactobacillus Drugs 0.000 title abstract 2
- 230000003389 potentiating effect Effects 0.000 title abstract 2
- 206010007134 Candida infections Diseases 0.000 abstract 1
- 241000218492 Lactobacillus crispatus Species 0.000 abstract 1
- 208000007027 Oral Candidiasis Diseases 0.000 abstract 1
- 241000287411 Turdidae Species 0.000 abstract 1
- 201000003984 candidiasis Diseases 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 208000019206 urinary tract infection Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
Abstract
La presente invención se refiere al uso de tiosulfato para potenciar el efecto anti-patogénico de bacterias lactobacilos; el tiosulfato se encuentra en una cantidad de por lo menos 100 mg para 107 a 1010 unidades formadoras de colonias de lactobacilos; la invención se refiere también a una composición farmacéutica que incluye por lo menos 100 mg de tiosulfato por gramo, en combinación con una cepa Lactobacillus crispatus y a su uso en el tratamiento de infecciones urogenitales tales como vaginosis, candidiasis e infecciones del tracto urinario.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1256570A FR2992861B1 (fr) | 2012-07-09 | 2012-07-09 | Utilisation de thiosulfate pour potentialiser l'effet anti-pathogene des lactobacilles |
PCT/EP2013/064451 WO2014009349A1 (fr) | 2012-07-09 | 2013-07-09 | Utilisation de thiosulfate pour potentialiser l'effet anti-pathogene des lactobacilles |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015000335A MX2015000335A (es) | 2015-07-14 |
MX360411B true MX360411B (es) | 2018-10-30 |
Family
ID=46826800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015000335A MX360411B (es) | 2012-07-09 | 2013-07-09 | Uso de tiosulfato para potenciar el efecto anti-patogenico de los lactobacilos. |
Country Status (16)
Country | Link |
---|---|
US (3) | US20150139969A1 (es) |
EP (1) | EP2869825B1 (es) |
KR (1) | KR101972198B1 (es) |
CN (2) | CN112999240A (es) |
AU (1) | AU2013289241A1 (es) |
BR (1) | BR112014033013A2 (es) |
CA (1) | CA2877666C (es) |
ES (1) | ES2604880T3 (es) |
FR (1) | FR2992861B1 (es) |
IN (1) | IN2014DN11238A (es) |
MX (1) | MX360411B (es) |
PL (1) | PL2869825T3 (es) |
RU (1) | RU2667122C2 (es) |
SA (1) | SA113340702B1 (es) |
TW (1) | TW201414481A (es) |
WO (1) | WO2014009349A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113564075A (zh) * | 2015-06-29 | 2021-10-29 | 辉凌制药公司 | 用于治疗例如细菌性阴道病的鼠李糖乳杆菌细菌 |
LU92820B1 (fr) * | 2015-09-08 | 2017-03-20 | Vesale Pharma International Sa | Composition comprenant au moins une bactérie probiotique et destinée à être utilisée pour le traitement de mycoses buccales |
FR3048361B1 (fr) * | 2016-03-01 | 2020-12-18 | Biose | Compositions pour le traitement des candidoses |
CN110799198A (zh) * | 2016-11-30 | 2020-02-14 | 普罗生物瑞士股份公司 | 用于稳定阴道液的酸度和氧化还原状态的基于合适的生化组合物的泌尿生殖器医疗设备制剂 |
CN112020359A (zh) | 2018-02-09 | 2020-12-01 | 分贝治疗公司 | 含有抗铂化学保护剂的高渗药物组合物 |
US10813947B1 (en) | 2019-05-31 | 2020-10-27 | Decibel Therapeutics, Inc. | Methods of otoprotection against platinum-based antineoplastic agents |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US691972A (en) * | 1901-07-29 | 1902-01-28 | F W Rueckheim & Brother | Knockdown paper box. |
FR1426226A (fr) * | 1964-11-20 | 1966-01-28 | Ct De Lyophilisation Pharma | Perfectionnements à la conservation des germes microbiens et en particulier des bacilles lactiques par lyophilisation |
DK242083D0 (da) | 1983-05-27 | 1983-05-27 | Hansens Chr Bio Syst | Vaginalkapsler |
ZA942302B (en) | 1993-12-03 | 1995-09-29 | Lafor Lab Ltd | Viracidal bactericidal and spermicidal vaginal suppository |
US6093394A (en) | 1997-04-11 | 2000-07-25 | Gynelogix, Inc. | Vaginal lactobacillus medicant |
EP0956858B1 (en) * | 1998-04-30 | 2001-10-31 | Renata Maria Anna Cavaliere Vesely | Pharmaceutical compositions containing Lactobacillus brevis and Lactobacillus salivarius for treatment of vaginal infections |
WO2000035465A2 (en) | 1998-12-11 | 2000-06-22 | Urex Biotech Inc. | Oral administration of lactobacillus for the treatment and prevention of urogenital infection |
US20020044926A1 (en) | 1999-12-10 | 2002-04-18 | Gregor Reid | Oral administration of lactobacillus for the treatment and prevention of urogenital infection |
US6653062B1 (en) * | 2000-07-26 | 2003-11-25 | Wisconsin Alumni Research Foundation | Preservation and storage medium for biological materials |
DE60229169D1 (de) * | 2002-03-13 | 2008-11-13 | Matsushita Electric Ind Co Ltd | Kühlvorrichtung |
JP4315831B2 (ja) * | 2004-02-17 | 2009-08-19 | 株式会社マンダム | 防腐殺菌剤並びに該防腐殺菌剤を配合した化粧料、医薬品及び食品 |
US7479481B2 (en) * | 2004-05-06 | 2009-01-20 | Molichem Medicines, Inc. | Treatment of ocular diseases and disorders using lantibiotic compositions |
SE528382C2 (sv) | 2004-10-05 | 2006-10-31 | Probi Ab | Probiotiska lactobacillusstammar för förbättrad vaginal hälsa |
JP4411181B2 (ja) * | 2004-10-22 | 2010-02-10 | キヤノン株式会社 | 画像形成装置 |
WO2006045347A1 (en) | 2004-10-22 | 2006-05-04 | Medinova Ag | Lactobacillus helveticus strain useful in the treatment or prevention of infections caused by urogenital pathogens |
NZ560257A (en) * | 2005-01-05 | 2010-10-29 | Chr Hansen Holding As | Use of compounds involved in biosynthesis of nucleic acids to increase yield of bacterial culture |
CN1888051B (zh) * | 2005-06-28 | 2010-05-05 | 北京天佑达生物工程科技有限公司 | 一株植物乳杆菌及其应用 |
ITMI20061912A1 (it) | 2006-10-04 | 2008-04-05 | S I I T Srl | Composizioni farmaceutiche topiche vaginali |
CN101033455A (zh) * | 2007-02-06 | 2007-09-12 | 中国农业科学院北京畜牧兽医研究所 | 一种低酸发酵加工用植物乳杆菌专用菌株及其发酵剂的制备方法 |
EP2211640A2 (en) | 2007-09-21 | 2010-08-04 | Kerry Group Services International Limited | A probiotic composition |
FR2933617B1 (fr) | 2008-07-10 | 2010-09-17 | Alliospharma | Compositions visant a favoriser le developpement et la croissance d'une microflore vaginale benefique |
CN107047934A (zh) * | 2008-09-17 | 2017-08-18 | 拜尔作物科学有限合伙公司 | 利用枯草芽孢杆菌菌株以增强动物健康的方法 |
US8329447B2 (en) * | 2008-12-12 | 2012-12-11 | Osel, Inc. | Strain of Lactobacillus crispatus |
EP2206506A1 (en) * | 2008-12-18 | 2010-07-14 | Bracco Imaging S.p.A | Probiotic formulations |
CN102438628A (zh) | 2009-05-22 | 2012-05-02 | 拜耳医药股份有限公司 | 包含至少一种雌激素和/或至少一种孕激素和至少一种益生菌菌株的供口服给药的药物 |
CN101919917A (zh) * | 2009-06-11 | 2010-12-22 | 张博 | 心脑肾康丸中成药 |
AU2010270605B2 (en) * | 2009-07-08 | 2014-07-31 | Hope Medical Enterprises, Inc. Dba Hope Pharmaceuticals | Sodium thiosulfate-containing pharmaceutical compositions |
ES2388478T3 (es) | 2009-12-02 | 2012-10-15 | Bettina Heil | Supositorio para la administración rectal, vaginal o uretral que contiene un probiótico, un antibiótico y un ácido graso insaturado no esterificado |
EP2428214A1 (en) * | 2010-09-14 | 2012-03-14 | HSO Health Care GmbH | Compositions for the vaginal and oral administration of lactobacillus and uses thereof |
CN102676429B (zh) * | 2012-05-11 | 2013-06-12 | 刘锋 | 一种耐高糖高酸的乳酸杆菌 |
CN103074270A (zh) * | 2012-11-15 | 2013-05-01 | 上海交大昂立股份有限公司 | 一种卷曲乳杆菌及其应用 |
-
2012
- 2012-07-09 FR FR1256570A patent/FR2992861B1/fr active Active
-
2013
- 2013-07-08 TW TW102124319A patent/TW201414481A/zh unknown
- 2013-07-09 RU RU2015103115A patent/RU2667122C2/ru active
- 2013-07-09 SA SA113340702A patent/SA113340702B1/ar unknown
- 2013-07-09 AU AU2013289241A patent/AU2013289241A1/en not_active Abandoned
- 2013-07-09 ES ES13734782.9T patent/ES2604880T3/es active Active
- 2013-07-09 BR BR112014033013A patent/BR112014033013A2/pt not_active IP Right Cessation
- 2013-07-09 CN CN202110179109.6A patent/CN112999240A/zh active Pending
- 2013-07-09 CA CA2877666A patent/CA2877666C/fr active Active
- 2013-07-09 US US14/413,660 patent/US20150139969A1/en not_active Abandoned
- 2013-07-09 WO PCT/EP2013/064451 patent/WO2014009349A1/fr active Application Filing
- 2013-07-09 CN CN201380039635.6A patent/CN104519892A/zh active Pending
- 2013-07-09 KR KR1020157003079A patent/KR101972198B1/ko active IP Right Grant
- 2013-07-09 EP EP13734782.9A patent/EP2869825B1/fr active Active
- 2013-07-09 PL PL13734782T patent/PL2869825T3/pl unknown
- 2013-07-09 MX MX2015000335A patent/MX360411B/es active IP Right Grant
-
2014
- 2014-12-30 IN IN11238DEN2014 patent/IN2014DN11238A/en unknown
-
2018
- 2018-02-19 US US15/899,273 patent/US11202799B2/en active Active
-
2021
- 2021-11-11 US US17/524,388 patent/US20220062330A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
ES2604880T3 (es) | 2017-03-09 |
BR112014033013A2 (pt) | 2017-06-27 |
US20150139969A1 (en) | 2015-05-21 |
KR20150029737A (ko) | 2015-03-18 |
SA113340702B1 (ar) | 2015-10-14 |
US11202799B2 (en) | 2021-12-21 |
TW201414481A (zh) | 2014-04-16 |
FR2992861B1 (fr) | 2014-10-17 |
CA2877666C (fr) | 2020-07-14 |
RU2667122C2 (ru) | 2018-09-14 |
CA2877666A1 (fr) | 2014-01-16 |
MX2015000335A (es) | 2015-07-14 |
US20180360874A1 (en) | 2018-12-20 |
US20220062330A1 (en) | 2022-03-03 |
KR101972198B1 (ko) | 2019-04-24 |
EP2869825B1 (fr) | 2016-08-24 |
CN112999240A (zh) | 2021-06-22 |
CN104519892A (zh) | 2015-04-15 |
FR2992861A1 (fr) | 2014-01-10 |
AU2013289241A1 (en) | 2015-01-29 |
IN2014DN11238A (es) | 2015-10-02 |
EP2869825A1 (fr) | 2015-05-13 |
WO2014009349A1 (fr) | 2014-01-16 |
PL2869825T3 (pl) | 2017-04-28 |
RU2015103115A (ru) | 2016-08-27 |
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