MX356750B - Composiciones farmaceuticas que contienen acido lactico oligomerico. - Google Patents

Composiciones farmaceuticas que contienen acido lactico oligomerico.

Info

Publication number
MX356750B
MX356750B MX2015000564A MX2015000564A MX356750B MX 356750 B MX356750 B MX 356750B MX 2015000564 A MX2015000564 A MX 2015000564A MX 2015000564 A MX2015000564 A MX 2015000564A MX 356750 B MX356750 B MX 356750B
Authority
MX
Mexico
Prior art keywords
lactic acid
oligomeric lactic
pharmaceutical compositions
compositions containing
containing oligomeric
Prior art date
Application number
MX2015000564A
Other languages
English (en)
Other versions
MX2015000564A (es
Inventor
Sterner Olov
Kulstad Sören
Robertsson Jeanette
Sznitowska Malgorzata
Schubert Werner
Original Assignee
Laccure Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laccure Ab filed Critical Laccure Ab
Publication of MX2015000564A publication Critical patent/MX2015000564A/es
Publication of MX356750B publication Critical patent/MX356750B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
    • C07C69/68—Lactic acid esters

Abstract

Una composición que comprende i) ácido láctico oligomérico con la siguiente fórmula (ver Fórmula) en donde n es un número entero de 2 a 20, de 2 a 19, o de 2 a 18, y en donde de aproximadamente 10 a aproximadamente 20% (p/p) del peso total del ácido láctico oligomérico es un trímero, HL3, que tiene n igual a 2, en donde el peso molecular promedio en número Mn del ácido láctico oligomérico es de aproximadamente 200 a aproximadamente 500, y ii) un agente mucoadhesivo.
MX2015000564A 2012-07-16 2013-07-05 Composiciones farmaceuticas que contienen acido lactico oligomerico. MX356750B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201270431 2012-07-16
PCT/EP2013/064265 WO2014012805A1 (en) 2012-07-16 2013-07-05 Pharmaceutical compositions containing oligomeric lactic acid

Publications (2)

Publication Number Publication Date
MX2015000564A MX2015000564A (es) 2015-04-10
MX356750B true MX356750B (es) 2018-06-12

Family

ID=48793207

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015000564A MX356750B (es) 2012-07-16 2013-07-05 Composiciones farmaceuticas que contienen acido lactico oligomerico.

Country Status (17)

Country Link
US (1) US9370502B2 (es)
EP (1) EP2872117B1 (es)
JP (1) JP6149109B2 (es)
KR (1) KR102089117B1 (es)
CN (1) CN104470498B (es)
AU (1) AU2013292179B2 (es)
BR (1) BR112015001006B1 (es)
CA (1) CA2875784C (es)
DK (1) DK2872117T3 (es)
ES (1) ES2652251T3 (es)
IN (1) IN2014DN09789A (es)
MX (1) MX356750B (es)
NO (1) NO2872117T3 (es)
PL (1) PL2872117T3 (es)
RU (1) RU2627470C2 (es)
WO (1) WO2014012805A1 (es)
ZA (1) ZA201409039B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2014DN08616A (es) 2012-03-30 2015-05-22 Borgwarner Inc
RU2709464C2 (ru) 2015-09-29 2019-12-18 Кимберли-Кларк Ворлдвайд, Инк. Синергическая композиция для сохранения здорового баланса микрофлоры
CN105327405B (zh) * 2015-10-23 2019-01-29 华南理工大学 用于治疗宫颈炎的载药支架及其制备方法
CN109288793B (zh) * 2018-07-27 2021-07-16 江苏中天药业有限公司 一种用于阴道pH环境调节的喷雾剂及其制备方法
WO2023165971A1 (en) 2022-03-01 2023-09-07 Laccure Ab Process for preparation of compositions of oligomers of lactic acid

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6552024B1 (en) * 1999-01-21 2003-04-22 Lavipharm Laboratories Inc. Compositions and methods for mucosal delivery
WO2003016259A2 (de) * 2001-08-16 2003-02-27 Pharmacon-Forschung Und Beratung Gmbh Milchsäureelemente enthaltende verbindungen, deren herstellung sowie deren verwendung als pharmazeutische wirkstoffe
SE528337C2 (sv) * 2004-06-23 2006-10-24 Nestor Medical Ab Sammansättning innefattande mjölksyra och laktoferrin, eller ett peptidfragment därav, och användning av denna sammansättning för behandling av tillstånd i urogenitalsystemet
RU2308951C2 (ru) * 2005-08-18 2007-10-27 Виктор Игоревич Высоков Комплексный способ профилактики вагинальных дисбактериозов (варианты)
WO2008062446A2 (en) * 2006-09-14 2008-05-29 Alembic Limited An extended release composition of levetiracetam, which exhibits no adverse food effect
CN101677980B (zh) * 2007-03-30 2013-10-23 莱克瑞股份公司 乳酸低聚物在制备用于治疗妇科病的药物中的应用

Also Published As

Publication number Publication date
CN104470498B (zh) 2017-08-08
CA2875784A1 (en) 2014-01-23
EP2872117B1 (en) 2017-09-27
BR112015001006A2 (pt) 2017-06-27
MX2015000564A (es) 2015-04-10
RU2015104974A (ru) 2016-09-10
DK2872117T3 (en) 2018-01-08
KR102089117B1 (ko) 2020-04-16
RU2627470C2 (ru) 2017-08-08
US9370502B2 (en) 2016-06-21
ZA201409039B (en) 2020-01-29
WO2014012805A1 (en) 2014-01-23
BR112015001006B1 (pt) 2022-05-17
JP6149109B2 (ja) 2017-06-14
CA2875784C (en) 2020-03-10
EP2872117A1 (en) 2015-05-20
AU2013292179A1 (en) 2015-01-15
KR20150036091A (ko) 2015-04-07
NO2872117T3 (es) 2018-02-24
AU2013292179B2 (en) 2017-03-30
CN104470498A (zh) 2015-03-25
ES2652251T3 (es) 2018-02-01
WO2014012805A9 (en) 2014-12-31
US20150164848A1 (en) 2015-06-18
JP2015526413A (ja) 2015-09-10
PL2872117T3 (pl) 2018-02-28
IN2014DN09789A (es) 2015-07-31

Similar Documents

Publication Publication Date Title
MY188960A (en) Cyclic boronic acid ester derivatives and therapeutic uses thereof
JOP20180102A1 (ar) مركب صيدلاني
MX2015008100A (es) Composiciones que comprenden un compuesto de triazol.
PH12015501385A1 (en) Autotaxin inhibitors
WO2011153157A3 (en) Benzoquinolone inhibitors of vmat2
WO2012135025A3 (en) Conjugated lipomers and uses thereof
UA110943C2 (uk) N-ацилсульфонамідні промотори апоптозу
MX349827B (es) Compuestos que contienen nitrogeno y su uso.
MX2015013806A (es) Polieteraminas a base de 1,3-dialcoholes.
GEP20186852B (en) Compositions comprising short-acting benzodiazepines
IN2014DN09789A (es)
MX2017014035A (es) Formas solidas novedosas.
MX2013004759A (es) Compuestos de oxima como agentes de elevacion de colesterol de lipoproteina de alta densidad (hdl).
MX2014004858A (es) Compuestos de 3,4-diamino-3-ciclobuten-1,2-diona disustituidos utiles en el tratamiento de patologias mediadas por quimiocinas.
MX2014015197A (es) Tratamiento y prevencion de la enfermedad cardiovascular y trombosis.
WO2013072528A3 (en) Substituted n-(tetrazol-5-yl)- and n-(triazol-5-yl)pyridin-3-yl-carboxamide compounds and their use as herbicides
WO2013061004A8 (fr) Nouveaux composés di-substitués de la diamino-3,4-cyclobutène-3-dione-1,2 utiles dans le traitement de pathologies médiées par des chimiokines
MX2013000474A (es) Derivados de arilamida novedosos que tienen propiedades antiandrogenicas.
MX2014013851A (es) Composiciones farmaceuticas topicas que comprenden terbinafina y urea.
WO2012174096A3 (en) Personal care compositions comprising a di-amido gellant and methods of using
PH12014502285A1 (en) Anti-malarial agents
EA201291014A1 (ru) Трициклическое индазольное соединение, способ его получения и содержащая его фармацевтическая композиция
MX2019012375A (es) Formulaciones del inhibidor del antigeno-1 asociado a la funcion de linfocitos (lfa-1).
MX2012007172A (es) Piperazinas como agentes antimalaria.
WO2013073998A3 (ru) Новые производные гемина с антибактериальной и противовирусной активностью

Legal Events

Date Code Title Description
FG Grant or registration