MX355478B - Formulaciones farmacéuticas resistentes a la manipulación. - Google Patents
Formulaciones farmacéuticas resistentes a la manipulación.Info
- Publication number
- MX355478B MX355478B MX2014003186A MX2014003186A MX355478B MX 355478 B MX355478 B MX 355478B MX 2014003186 A MX2014003186 A MX 2014003186A MX 2014003186 A MX2014003186 A MX 2014003186A MX 355478 B MX355478 B MX 355478B
- Authority
- MX
- Mexico
- Prior art keywords
- pharmaceutical formulations
- tamper resistant
- resistant pharmaceutical
- dosage form
- active agent
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 3
- 239000013543 active substance Substances 0.000 abstract 2
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000003349 gelling agent Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000006186 oral dosage form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Addiction (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161535743P | 2011-09-16 | 2011-09-16 | |
| PCT/IB2012/001914 WO2013038267A1 (en) | 2011-09-16 | 2012-09-14 | Tamper resistant pharmaceutical formulations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014003186A MX2014003186A (es) | 2015-10-12 |
| MX355478B true MX355478B (es) | 2018-04-19 |
Family
ID=47018275
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014003186A MX355478B (es) | 2011-09-16 | 2012-09-14 | Formulaciones farmacéuticas resistentes a la manipulación. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20140341984A1 (OSRAM) |
| EP (1) | EP2755640B1 (OSRAM) |
| JP (1) | JP6110384B2 (OSRAM) |
| AU (1) | AU2012310250B2 (OSRAM) |
| CA (1) | CA2847611A1 (OSRAM) |
| ES (1) | ES2641437T3 (OSRAM) |
| IL (1) | IL231485A (OSRAM) |
| MX (1) | MX355478B (OSRAM) |
| WO (1) | WO2013038267A1 (OSRAM) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003024429A1 (en) | 2001-09-21 | 2003-03-27 | Egalet A/S | Polymer release system |
| US20040253310A1 (en) | 2001-09-21 | 2004-12-16 | Gina Fischer | Morphine polymer release system |
| EP1610767B1 (en) | 2003-03-26 | 2011-01-19 | Egalet A/S | Morphine controlled release system |
| US8445018B2 (en) | 2006-09-15 | 2013-05-21 | Cima Labs Inc. | Abuse resistant drug formulation |
| WO2008148798A2 (en) | 2007-06-04 | 2008-12-11 | Egalet A/S | Controlled release pharmaceutical compositions for prolonged effect |
| CA2751667C (en) | 2009-02-06 | 2016-12-13 | Egalet Ltd. | Immediate release composition resistant to abuse by intake of alcohol |
| EP2445487A2 (en) | 2009-06-24 | 2012-05-02 | Egalet Ltd. | Controlled release formulations |
| EA028224B1 (ru) * | 2012-03-02 | 2017-10-31 | Роудс Фармасьютикалз Л.П. | Лекарственные формы немедленного высвобождения с защитой от несанкционированного применения |
| HRP20181716T1 (hr) * | 2012-04-18 | 2018-12-28 | Grünenthal GmbH | Farmaceutski oblik doziranja otporan na zlonamjernu uporabu i naglo oslobađanje cjelokupne doze |
| MX2014015880A (es) | 2012-07-06 | 2015-08-05 | Egalet Ltd | Composiciones farmaceuticas disuasivas de abuso para liberacion controlada. |
| WO2015023675A2 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| US10172797B2 (en) | 2013-12-17 | 2019-01-08 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| AU2015290098B2 (en) | 2014-07-17 | 2018-11-01 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
| US9132096B1 (en) | 2014-09-12 | 2015-09-15 | Alkermes Pharma Ireland Limited | Abuse resistant pharmaceutical compositions |
| AU2015336065A1 (en) | 2014-10-20 | 2017-05-04 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| US12053464B2 (en) | 2017-10-20 | 2024-08-06 | Purdue Pharma L.P. | Pharmaceutical dosage forms |
| EP3727384A4 (en) | 2017-12-20 | 2021-11-03 | Purdue Pharma L.P. | ABUSE-DISSUASIVE MORPHINE SULPHATE FORMES |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK150008C (da) * | 1981-11-20 | 1987-05-25 | Benzon As Alfred | Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat |
| US5965161A (en) * | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
| BR0212020A (pt) * | 2001-08-06 | 2005-08-16 | Euro Celtique Sa | Formas de dosagem, métodos para impedir o abuso de uma forma de dosagem, métodos para impedir o desvio de uma forma de dosagem, métodos para o tratamento de dor e método de preparação de uma forma de dosagem |
| US20030068375A1 (en) * | 2001-08-06 | 2003-04-10 | Curtis Wright | Pharmaceutical formulation containing gelling agent |
| DE10336400A1 (de) * | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| EP1677766B1 (de) * | 2003-10-31 | 2012-03-14 | Hexal AG | Pharmazeutische wirkstoffhaltige formulierung mit überzug |
| TWI483944B (zh) | 2004-03-30 | 2015-05-11 | Euro Celtique Sa | 含有小於２５ｐｐｍ１４-羥可待因酮之羥可酮鹽酸鹽組成物、醫藥劑型、延遲釋出口服劑型及醫藥上可以接受的包裝 |
| US20060177380A1 (en) * | 2004-11-24 | 2006-08-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of orally administered pharmaceutical products |
| US20080152595A1 (en) * | 2004-11-24 | 2008-06-26 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of orally administered pharmaceutical products |
| AP2274A (en) * | 2005-01-28 | 2011-08-19 | Euro Celtiques Sa | Alcohol resistant dosage forms. |
| US20090022798A1 (en) * | 2007-07-20 | 2009-01-22 | Abbott Gmbh & Co. Kg | Formulations of nonopioid and confined opioid analgesics |
| US9023400B2 (en) * | 2006-05-24 | 2015-05-05 | Flamel Technologies | Prolonged-release multimicroparticulate oral pharmaceutical form |
| SA07280459B1 (ar) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
| ATE530170T1 (de) * | 2007-08-21 | 2011-11-15 | Teva Pharma | Paliperidonformulierung mit verzögerter freisetzung |
| GB0909680D0 (en) * | 2009-06-05 | 2009-07-22 | Euro Celtique Sa | Dosage form |
| US8808740B2 (en) * | 2010-12-22 | 2014-08-19 | Purdue Pharma L.P. | Encased tamper resistant controlled release dosage forms |
-
2012
- 2012-09-14 EP EP12813950.8A patent/EP2755640B1/en active Active
- 2012-09-14 CA CA2847611A patent/CA2847611A1/en not_active Abandoned
- 2012-09-14 JP JP2014530331A patent/JP6110384B2/ja active Active
- 2012-09-14 WO PCT/IB2012/001914 patent/WO2013038267A1/en not_active Ceased
- 2012-09-14 ES ES12813950.8T patent/ES2641437T3/es active Active
- 2012-09-14 AU AU2012310250A patent/AU2012310250B2/en active Active
- 2012-09-14 MX MX2014003186A patent/MX355478B/es active IP Right Grant
- 2012-09-14 US US14/344,279 patent/US20140341984A1/en not_active Abandoned
-
2014
- 2014-03-12 IL IL231485A patent/IL231485A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013038267A1 (en) | 2013-03-21 |
| ES2641437T3 (es) | 2017-11-10 |
| IL231485A0 (en) | 2014-04-30 |
| WO2013038267A8 (en) | 2014-04-24 |
| AU2012310250A1 (en) | 2013-05-02 |
| JP6110384B2 (ja) | 2017-04-05 |
| CA2847611A1 (en) | 2013-03-21 |
| IL231485A (en) | 2017-03-30 |
| MX2014003186A (es) | 2015-10-12 |
| US20140341984A1 (en) | 2014-11-20 |
| AU2012310250B2 (en) | 2016-03-03 |
| EP2755640B1 (en) | 2017-07-26 |
| EP2755640A1 (en) | 2014-07-23 |
| JP2014526497A (ja) | 2014-10-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX355478B (es) | Formulaciones farmacéuticas resistentes a la manipulación. | |
| MX347961B (es) | Formulaciones de liberación inmediata resistentes a alteración. | |
| NZ629468A (en) | Tamper resistant immediate release formulations | |
| PH12013500477A1 (en) | Aqueous drug delivery system comprising off-flavor masking agent | |
| WO2013101897A3 (en) | Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid | |
| MX343867B (es) | Paquete de dosificacion unitaria y metodos para administrar medicaciones de perdida de peso. | |
| PH12015501756A1 (en) | Tamper resistant pharmaceutical formulations | |
| EA200802012A1 (ru) | Фармацевтические препараты в форме раствора для дозирующих ингаляторов под давлением | |
| WO2007134292A3 (en) | Treprostinil administration using a metered dose inhaler | |
| MX2014004279A (es) | Composiciones que comprenden sulfato de salbutamol. | |
| TN2015000326A1 (en) | Tamper resistant pharmaceutical formulations | |
| UA107499C2 (uk) | Склад сухого порошку, який містить антимускариновий засіб | |
| MX368774B (es) | Nueva dosificación y formulación. | |
| MX2014004364A (es) | Composiciones que comprenden sulfato de salbutamol. | |
| DE602008006700D1 (OSRAM) | ||
| BR112014014795A2 (pt) | sistema de pélete de multiunidade de liberação imediata | |
| PH12014502619A1 (en) | Novel dosage and formulation | |
| MX2015008068A (es) | Unidad solida con alto contenido en fexofenadina y su procedimiento de preparacion. | |
| AU2014226192A8 (en) | Dry pharmaceutical compositions comprising active agent nanoparticles bound to carrier particles | |
| MX2015009891A (es) | Composiciones farmaceuticas que comprenden particulas cristalinas de multicomponentes adecuadas para usar en terapia de inhalacion. | |
| UA80243U (ru) | Система доставки лекарств | |
| IN2013MU03390A (OSRAM) | ||
| UA97524C2 (ru) | Лекарственный препарат противосудорожного действия топиромата в форме таблеток и его кристаллический состав |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |