MX349235B - Anticuerpos monoclonales específicos para el antígeno m2-1 del virus respiratorio sincicial (vrs). - Google Patents

Anticuerpos monoclonales específicos para el antígeno m2-1 del virus respiratorio sincicial (vrs).

Info

Publication number
MX349235B
MX349235B MX2014006248A MX2014006248A MX349235B MX 349235 B MX349235 B MX 349235B MX 2014006248 A MX2014006248 A MX 2014006248A MX 2014006248 A MX2014006248 A MX 2014006248A MX 349235 B MX349235 B MX 349235B
Authority
MX
Mexico
Prior art keywords
rsv
monoclonal antibodies
antigen
respiratory syncytial
syncytial virus
Prior art date
Application number
MX2014006248A
Other languages
English (en)
Other versions
MX2014006248A (es
Inventor
Mikes Kalergis Parra Alexis
Marcela Bueno Ramírez Susan
Eugenio Mora Alarcón Jorge
Sebastián Gómez Johnson Roberto
Original Assignee
Pontificia Univ Católica De Chile
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pontificia Univ Católica De Chile filed Critical Pontificia Univ Católica De Chile
Publication of MX2014006248A publication Critical patent/MX2014006248A/es
Publication of MX349235B publication Critical patent/MX349235B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/11—Paramyxoviridae (F); Pneumoviridae (F), e.g. respiratory syncytial virus [RSV]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/115—Paramyxoviridae, e.g. parainfluenza virus
    • G01N2333/135—Respiratory syncytial virus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pulmonology (AREA)

Abstract

La presente invención se refiere a el uso de un anticuerpos monoclonales específicos para el virus respiratorio sincicial (VRS). Concretamente, a los anticuerpos monoclonales que reconocen la proteína M2-1 del virus respiratorio sincicial humano (VRS), útiles para el desarrollo de métodos de diagnóstico de infección por VRS y para la producción de composiciones farmacéuticas destinadas al tratamiento y/o profilaxis de la infección por VRS.
MX2014006248A 2011-11-25 2012-11-23 Anticuerpos monoclonales específicos para el antígeno m2-1 del virus respiratorio sincicial (vrs). MX349235B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CL2011003002A CL2011003002A1 (es) 2011-11-25 2011-11-25 Anticuerpo monoclonal o un fragmento del mismo que se une a la proteina m2-1 del virus respiratorio sincicial (vrs) humano; secuencias nucleotidicas; composicion farmaceutica; metodo de diagnostico de infeccion producida por vrs; kit; y uso de dicho anticuerpo para preparar un medicamento.
PCT/IB2012/056688 WO2013076702A2 (es) 2011-11-25 2012-11-23 Anticuerpos monoclonales específicos para el antígeno m2-1 del virus respiratorio sincicial (vrs)

Publications (2)

Publication Number Publication Date
MX2014006248A MX2014006248A (es) 2015-03-03
MX349235B true MX349235B (es) 2017-07-19

Family

ID=51205767

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014006248A MX349235B (es) 2011-11-25 2012-11-23 Anticuerpos monoclonales específicos para el antígeno m2-1 del virus respiratorio sincicial (vrs).

Country Status (13)

Country Link
US (1) US9273122B2 (es)
EP (1) EP2784088B1 (es)
CN (1) CN103998465B (es)
AR (1) AR088987A1 (es)
CA (1) CA2856258C (es)
CL (1) CL2011003002A1 (es)
ES (1) ES2657619T3 (es)
IN (1) IN2014CN04823A (es)
MX (1) MX349235B (es)
PE (1) PE20141683A1 (es)
PT (1) PT2784088T (es)
WO (1) WO2013076702A2 (es)
ZA (1) ZA201403564B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2014003373A1 (es) * 2014-12-11 2015-04-10 Univ Pontificia Catolica Chile Anticuerpos monoclonales especificos para el antígeno m del virus metapneumovirus humano (hmpv), producidos y secretados por hibridomas celulares , útiles para la deteccion y el diagnostico de la infeccion causada por hmpv.
JP6270781B2 (ja) * 2015-06-30 2018-01-31 田中貴金属工業株式会社 クロマト分析装置およびクロマト分析方法
CL2015002152A1 (es) 2015-07-31 2016-06-03 Pontificia Universidad Católica De Chile Anticuerpos monoclonales específicos para el antígeno p del virus respiratorio sincicial humano (vrsh), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnostico de la infección causada por vrsh
TWI761453B (zh) 2017-03-01 2022-04-21 英商梅迪繆思有限公司 抗rsv單株抗體配製物
US12065484B2 (en) 2018-09-03 2024-08-20 Pontificia Universidad Catolica De Chile Specific monoclonal antibody against the N antigen of human respiratory syncytial virus (hRSV) useful for treating infection, detection thereof and diagnosis
RU2713340C1 (ru) * 2018-12-28 2020-02-04 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт гриппа имени А.А. Смородинцева" Министерства здравоохранения Российской Федерации Моноклональные антитела, специфичные к различным штаммам респираторно-синцитиального вируса
CN115838419B (zh) * 2022-09-27 2023-06-30 深圳重链生物科技有限公司 抗呼吸道合胞病毒抗体及其相关应用
CN119546630A (zh) * 2022-12-08 2025-02-28 南京诺唯赞生物科技股份有限公司 特异性结合rsv的抗体

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU686113B2 (en) * 1992-09-16 1998-02-05 Scripps Research Institute, The Human neutralizing monoclonal antibodies to respiratory syncytial virus
NZ269735A (en) * 1993-07-30 1998-01-26 Oravax Inc Monoclonal iga antibody against respiratory syncytial virus (rsv)
WO2000050646A1 (en) * 1999-02-26 2000-08-31 The Uab Research Foundation Methods of screening for antiviral compounds
US20020068066A1 (en) * 1999-08-20 2002-06-06 Wenyuan Shi Method for the treatment and prevention of dental caries
DK1340086T3 (da) 2000-10-17 2008-12-01 Besst Test Aps Assay til direkte detektion af en RS-virusrelateret biologisk celle i en legemsvæskepröve
JP2007531491A (ja) * 2002-09-27 2007-11-08 メディミューン・ヴァクシンズ・インコーポレーテッド 呼吸器合胞体ウイルスにおける機能的突然変異
CN101130765B (zh) 2006-08-21 2011-04-06 北京阿斯可来生物工程有限公司 呼吸道合胞病毒检测试剂盒
KR100938998B1 (ko) 2008-01-08 2010-01-28 (주) 에이프로젠 호흡기 신시티움 바이러스에 대한 항체

Also Published As

Publication number Publication date
AR088987A1 (es) 2014-07-23
BR112014012608A2 (pt) 2020-10-27
CN103998465A (zh) 2014-08-20
EP2784088B1 (en) 2017-10-25
CL2011003002A1 (es) 2012-05-25
EP2784088A2 (en) 2014-10-01
WO2013076702A2 (es) 2013-05-30
PE20141683A1 (es) 2014-11-28
CN103998465B (zh) 2017-02-22
EP2784088A4 (en) 2015-05-13
ES2657619T3 (es) 2018-03-06
CA2856258A1 (en) 2013-05-30
PT2784088T (pt) 2018-01-31
CA2856258C (en) 2018-05-01
US9273122B2 (en) 2016-03-01
US20140348858A1 (en) 2014-11-27
ZA201403564B (en) 2015-08-26
MX2014006248A (es) 2015-03-03
IN2014CN04823A (es) 2015-09-18
WO2013076702A3 (es) 2013-07-25

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