MX348708B - Métodos para mejorar el desarrollo del cerebro y la función cognoscitiva al usar beta-hidroxi-beta-metilbutirato. - Google Patents
Métodos para mejorar el desarrollo del cerebro y la función cognoscitiva al usar beta-hidroxi-beta-metilbutirato.Info
- Publication number
- MX348708B MX348708B MX2013009528A MX2013009528A MX348708B MX 348708 B MX348708 B MX 348708B MX 2013009528 A MX2013009528 A MX 2013009528A MX 2013009528 A MX2013009528 A MX 2013009528A MX 348708 B MX348708 B MX 348708B
- Authority
- MX
- Mexico
- Prior art keywords
- beta
- methods
- methylbutyrate
- hydroxy
- cognitive function
- Prior art date
Links
- AXFYFNCPONWUHW-UHFFFAOYSA-N 3-hydroxyisovaleric acid Chemical compound CC(C)(O)CC(O)=O AXFYFNCPONWUHW-UHFFFAOYSA-N 0.000 title 1
- 230000004641 brain development Effects 0.000 title 1
- 230000003920 cognitive function Effects 0.000 title 1
- 208000010877 cognitive disease Diseases 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 230000001537 neural effect Effects 0.000 abstract 2
- 235000016709 nutrition Nutrition 0.000 abstract 2
- 208000028698 Cognitive impairment Diseases 0.000 abstract 1
- 230000006999 cognitive decline Effects 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000006870 function Effects 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Nutrition Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pediatric Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
La presente invención se refiere a una composición que comprende beta-hidroxi-beta-mutilbutirato para usarse en mejorar la cognición en un adulto mayor. Una composición que comprende beta-hidroxi-beta-metilbutirato para usarse en el tratamiento de una enfermedad cognitiva asociada con una enfermedad neurodegenerativa en un adulto mayor. Una composición que comprende beta-hidroxi-beta-metilbutirato para usarse en mejorar la función cognitiva en un infante, niño o adolescente.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161443762P | 2011-02-17 | 2011-02-17 | |
| PCT/US2012/024817 WO2012112419A1 (en) | 2011-02-17 | 2012-02-13 | Methods for improving brain development and cognitive function using beta-hydroxy-beta-methylbutyrate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013009528A MX2013009528A (es) | 2013-10-01 |
| MX348708B true MX348708B (es) | 2017-06-26 |
Family
ID=45757211
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013009528A MX348708B (es) | 2011-02-17 | 2012-02-13 | Métodos para mejorar el desarrollo del cerebro y la función cognoscitiva al usar beta-hidroxi-beta-metilbutirato. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9326956B2 (es) |
| EP (1) | EP2675298A1 (es) |
| JP (2) | JP6034309B2 (es) |
| CN (1) | CN103347406B (es) |
| AR (1) | AR085297A1 (es) |
| BR (1) | BR112013020643A2 (es) |
| CA (1) | CA2825734C (es) |
| MX (1) | MX348708B (es) |
| PH (1) | PH12013501671A1 (es) |
| SG (1) | SG192813A1 (es) |
| TW (1) | TWI565420B (es) |
| WO (1) | WO2012112419A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2012008785A (es) | 2010-01-29 | 2012-08-17 | Abbott Lab | Emulsiones nutricionales que comprenden beta-hidroxi-beta-metilbut irato (hmb) de calcio. |
| US9693577B2 (en) | 2010-01-29 | 2017-07-04 | Abbott Laboratories | Method of preparing a nutritional powder comprising spray dried HMB |
| SG182808A1 (en) | 2010-01-29 | 2012-09-27 | Abbott Lab | Aseptically packaged nutritional liquids comprising hmb |
| TWI526161B (zh) | 2010-06-10 | 2016-03-21 | 亞培公司 | 包含鈣hmb及可溶性蛋白質之實質上透明營養液 |
| CN103347406B (zh) | 2011-02-17 | 2015-08-05 | 雅培制药有限公司 | 使用β-羟基-β-甲基丁酸盐改善脑部发育和认知功能的方法 |
| ES2421187B1 (es) * | 2012-02-23 | 2014-11-26 | Abbott Laboratories | Metodo para mejorar el desarrollo cerebral y la funcion cognitiva usando beta-hidroxi-beta-metilbutirato |
| EP2745708A1 (en) * | 2012-12-24 | 2014-06-25 | Abbott Laboratories, Inc. | Antidepressant effect of ß-hydroxy-ß-methylbutyrate |
| WO2014120730A2 (en) * | 2013-01-29 | 2014-08-07 | Otc Nutrition Llc | Micronutrient fortification delivery |
| WO2014127112A1 (en) * | 2013-02-13 | 2014-08-21 | Baylor College Of Medicine | Memory enhancer and actin dynamics |
| CN105357984A (zh) * | 2013-03-15 | 2016-02-24 | 雅培制药有限公司 | 低卡路里婴儿配制品含有 |
| EP3122348B1 (en) | 2014-03-27 | 2020-05-27 | Winterfield, Roland, W. | Beta-hydroxy beta-methylbutyrate for alleviating statin myopathy |
| WO2017048708A1 (en) * | 2015-09-16 | 2017-03-23 | Abbott Laboratories | Reduced fat, shelf stable liquid nutritional composition |
| EP3373740B9 (en) * | 2015-11-10 | 2021-07-21 | Metabolic Technologies, Inc. | Compositions and methods of use of -hydroxy- -methylbutyrate (hmb) as an animal feed additive |
| JP7011300B2 (ja) * | 2017-12-19 | 2022-02-10 | 株式会社島田製薬 | HMBCa含有顆粒の製造方法、及びサプリメント |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6291525B1 (en) | 1999-09-08 | 2001-09-18 | Iowa State University Research Foundation, Inc. | Method for improving a human's perception of his emotional state |
| US7445807B2 (en) * | 2002-10-15 | 2008-11-04 | Western Holdings, Llc | Agglomerated granular protein-rich nutritional supplement |
| US20050027005A1 (en) | 2003-08-02 | 2005-02-03 | Matthias Boldt | Nutrient compositions and methods for sustenance and promotion of positive metabolic energy levels in a targeted manner |
| US20050215640A1 (en) | 2004-03-26 | 2005-09-29 | Baxter Jeffrey H | HMB compositions and uses thereof |
| PL371081A1 (pl) * | 2004-11-08 | 2006-05-15 | Sgp & Sons Ab | Preparat farmaceutyczny wpływający na procesy wzrostu i mineralizacji układu kostno-szkieletowego oraz chorób kości i chrząstki wieku dojrzałego u ludzi i zwierząt oraz zastosowanie preparatu farmaceutycznego w procesie wzrostu i mineralizacji układu kostno-szkieletowego oraz chorób kości i chrząstki wieku dojrzałego u ludzi i zwierząt |
| US20060167075A1 (en) | 2005-01-25 | 2006-07-27 | Pearson James P | Modulators of FAAH |
| WO2007056176A2 (en) * | 2005-11-03 | 2007-05-18 | Southwest Immunology, Inc. | Compositions for preventing and reducing delayed onset muscle soreness |
| WO2007075605A2 (en) * | 2005-12-19 | 2007-07-05 | Abbott Laboratories | Use of beta-hydroxy-beta-methylbutyrate to modulate the imbalance in type and type 2 cytokine production |
| JP5630750B2 (ja) | 2008-03-18 | 2014-11-26 | 国立大学法人 岡山大学 | 興奮性化学伝達調節剤およびそのスクリーニング法 |
| PT2381784T (pt) | 2008-12-09 | 2018-10-30 | Metabolic Tech Inc | Intervenção nutricional para melhorar função e força muscular |
| JP2009155336A (ja) * | 2009-03-31 | 2009-07-16 | Tsujido Chemical Corp | 治療剤 |
| TW201117736A (en) | 2009-11-17 | 2011-06-01 | Hui-Chiang Lu | Compositions for sport supplement |
| CN101785566A (zh) * | 2010-01-22 | 2010-07-28 | 北京康比特体育科技股份有限公司 | 一种含有hmb的运动饮料 |
| JP2014501530A (ja) | 2010-12-22 | 2014-01-23 | アボット・ラボラトリーズ | カルシウムベータ−ヒドロキシ−ベータメチルブチレートと共役リノール酸とを含む栄養補助製品 |
| WO2012092035A1 (en) | 2010-12-27 | 2012-07-05 | Abbott Laboratories | Methods for facilitating muscle recovery after a period of disuse using beta-hydroxy-beta-methylbutyrate |
| CN103347406B (zh) | 2011-02-17 | 2015-08-05 | 雅培制药有限公司 | 使用β-羟基-β-甲基丁酸盐改善脑部发育和认知功能的方法 |
| US20150025143A1 (en) | 2012-03-19 | 2015-01-22 | Abbott Laboratories | Beta-hydroxy-beta-methylbutyric acid for improving glucose tolerance |
| EP2895013A1 (en) | 2012-09-17 | 2015-07-22 | Abbott Laboratories | Beta-hydroxy-beta-methylbutryic acid- containing compositions and uses thereof |
-
2012
- 2012-02-13 CN CN201280009207.4A patent/CN103347406B/zh not_active Expired - Fee Related
- 2012-02-13 PH PH1/2013/501671A patent/PH12013501671A1/en unknown
- 2012-02-13 US US13/984,906 patent/US9326956B2/en not_active Expired - Fee Related
- 2012-02-13 JP JP2013554520A patent/JP6034309B2/ja not_active Expired - Fee Related
- 2012-02-13 MX MX2013009528A patent/MX348708B/es active IP Right Grant
- 2012-02-13 CA CA2825734A patent/CA2825734C/en not_active Expired - Fee Related
- 2012-02-13 BR BR112013020643A patent/BR112013020643A2/pt not_active IP Right Cessation
- 2012-02-13 EP EP12705748.7A patent/EP2675298A1/en not_active Withdrawn
- 2012-02-13 SG SG2013062377A patent/SG192813A1/en unknown
- 2012-02-13 WO PCT/US2012/024817 patent/WO2012112419A1/en not_active Ceased
- 2012-02-17 TW TW101105347A patent/TWI565420B/zh not_active IP Right Cessation
- 2012-02-17 AR ARP120100566 patent/AR085297A1/es not_active Application Discontinuation
-
2016
- 2016-10-26 JP JP2016209276A patent/JP6340394B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| MX2013009528A (es) | 2013-10-01 |
| WO2012112419A8 (en) | 2014-03-06 |
| US9326956B2 (en) | 2016-05-03 |
| CN103347406A (zh) | 2013-10-09 |
| JP6034309B2 (ja) | 2016-11-30 |
| AR085297A1 (es) | 2013-09-18 |
| JP6340394B2 (ja) | 2018-06-06 |
| SG192813A1 (en) | 2013-09-30 |
| BR112013020643A2 (pt) | 2016-08-02 |
| CA2825734A1 (en) | 2012-08-23 |
| PH12013501671A1 (en) | 2021-06-02 |
| WO2012112419A1 (en) | 2012-08-23 |
| CN103347406B (zh) | 2015-08-05 |
| US20140249223A1 (en) | 2014-09-04 |
| TWI565420B (zh) | 2017-01-11 |
| JP2017061483A (ja) | 2017-03-30 |
| CA2825734C (en) | 2016-05-17 |
| JP2014506890A (ja) | 2014-03-20 |
| EP2675298A1 (en) | 2013-12-25 |
| TW201309212A (zh) | 2013-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |