MX336462B - Polimero no digerible: recubrimientos de pelicula basados en acetato de almidon dirigidos al colon. - Google Patents

Polimero no digerible: recubrimientos de pelicula basados en acetato de almidon dirigidos al colon.

Info

Publication number
MX336462B
MX336462B MX2012012557A MX2012012557A MX336462B MX 336462 B MX336462 B MX 336462B MX 2012012557 A MX2012012557 A MX 2012012557A MX 2012012557 A MX2012012557 A MX 2012012557A MX 336462 B MX336462 B MX 336462B
Authority
MX
Mexico
Prior art keywords
starch acetate
based film
film coatings
colon targeting
indigestible
Prior art date
Application number
MX2012012557A
Other languages
English (en)
Other versions
MX2012012557A (es
Inventor
Daniel Wils
Laëtitia Guerin-Deremaux
Juergen Siepmann
Youness Karrout
Jérôme Klaeyle
Original Assignee
Roquette Freres
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roquette Freres filed Critical Roquette Freres
Publication of MX2012012557A publication Critical patent/MX2012012557A/es
Publication of MX336462B publication Critical patent/MX336462B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a una forma de dosificación de administración dirigida al colon para la liberación controlada de un ingrediente activo en el colon de pacientes que tienen un desequilibrio de la microflora colónica o en el colon de sujetos saludables, caracterizados porque el ingrediente activo está recubierto con una mezcla polimérica de: una composición de polímero insoluble en agua que contiene al menos un acetato de almidón, y una composición de polisacárido no digerible que comprende al menos un polisacárido no digerible seleccionado del grupo que consiste en almidón, xilooligosacáridos, inulina , oligofructosas, fructo-oligosacáridos (FOS), lactulosa, galactomanano e hidrolizados adecuados del mismo, polidextrosa no digerible, dextrina no digerible e hidrolizados parciales de la misma, trans-galacto-oligosacáridos (GOS), xilooligosacáridos (XOS), acemanano, lentinán o beta glucano e hidrolizados parciales de los mismos, polisacáridos-K(PSK), y maltodextrina no digerible e hidrolizados parciales de la misma.
MX2012012557A 2010-04-28 2011-04-28 Polimero no digerible: recubrimientos de pelicula basados en acetato de almidon dirigidos al colon. MX336462B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10305452A EP2386297A1 (en) 2010-04-28 2010-04-28 Indigestible polymer: starch acetate -based film coatings for colon targeting
PCT/EP2011/056794 WO2011135055A1 (en) 2010-04-28 2011-04-28 Indigestible polymer: starch acetate -based film coatings for colon targeting

Publications (2)

Publication Number Publication Date
MX2012012557A MX2012012557A (es) 2012-11-23
MX336462B true MX336462B (es) 2016-01-20

Family

ID=43063550

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012012557A MX336462B (es) 2010-04-28 2011-04-28 Polimero no digerible: recubrimientos de pelicula basados en acetato de almidon dirigidos al colon.

Country Status (10)

Country Link
US (1) US20130078289A1 (es)
EP (2) EP2386297A1 (es)
JP (1) JP5875196B2 (es)
KR (1) KR20130072203A (es)
CN (1) CN102883714B (es)
BR (1) BR112012027447B1 (es)
CA (1) CA2796955A1 (es)
MX (1) MX336462B (es)
RU (1) RU2012150803A (es)
WO (1) WO2011135055A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2179727B1 (en) * 2008-10-27 2013-05-29 Roquette Freres Water insoluble polymer: modified starch derivative-based film coatings for colon targeting
FR2951177B1 (fr) * 2009-10-09 2012-12-21 Roquette Freres Procede de preparation de derives acetyles de matiere amylacee
EP3331507A1 (en) * 2015-08-06 2018-06-13 Roquette Freres Film-forming compositions based on starchy material and articles obtained thereof

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3795670A (en) 1973-03-05 1974-03-05 Us Agriculture Process for making starch triacetates
GB8926639D0 (en) * 1989-11-24 1990-01-17 Agricultural & Food Res Delayed release formulations
US5236719A (en) * 1991-09-27 1993-08-17 Wm. Wrigley Jr. Company Chewing gum and other comestibles containing purified indigestible dextrin
US5545450A (en) * 1992-08-11 1996-08-13 E. Khashoggi Industries Molded articles having an inorganically filled organic polymer matrix
US5321132A (en) 1992-12-23 1994-06-14 National Starch And Chemical Investment Holding Corporation Method of preparing intermediate DS starch esters in aqueous solution
FI942686A0 (fi) 1994-06-07 1994-06-07 Alko Ab Oy Komposition innehaollande staerkelseacetat med varierande egenskaper, foerfarande foer dess framstaellning och anvaendning
US5656292A (en) * 1994-06-07 1997-08-12 Alko Group Ltd. Composition for pH dependent controlled release of active ingredients and methods for producing it
ATE262006T1 (de) 1995-07-12 2004-04-15 Valtion Teknillinen Thermoplastifizierte stärke und verfahren zur herstellung
FI107386B (fi) 1996-12-31 2001-07-31 Valtion Teknillinen Menetelmä tärkkelysesterien valmistamiseksi
FI107930B (fi) 1996-12-31 2001-10-31 Valtion Teknillinen Hydroksialkyloitu tärkkelysesteri, sen valmistus ja käyttö
FR2786775B1 (fr) 1998-12-04 2001-02-16 Roquette Freres Maltodextrines branchees et leur procede de preparation
IT1318597B1 (it) * 2000-06-23 2003-08-27 A C R Applied Coating Res S A Uso di un amido ad alto contenuto di amilosio acetilato epregelatinizzato.
US6607748B1 (en) * 2000-06-29 2003-08-19 Vincent Lenaerts Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture
FI113874B (fi) * 2002-09-27 2004-06-30 Valtion Teknillinen Polymeeriliuokset ja -dispersiot ja menetelmä niiden valmistamiseksi
US8168228B2 (en) * 2003-10-17 2012-05-01 Sandoz Ag Antibiotic clarithromycin micropellet compositions
FR2862654B1 (fr) * 2003-11-20 2006-02-10 Roquette Freres Composition amylacee filmogene
US9149439B2 (en) * 2005-03-21 2015-10-06 Sandoz Ag Multi-particulate, modified-release composition
FR2884422B1 (fr) * 2005-04-18 2008-04-11 Roquette Freres Composition anti-inflammatoire de l'intestin comprenant des maltodextrines branchees
US9198871B2 (en) * 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
CN100518830C (zh) * 2006-07-12 2009-07-29 华南理工大学 变性淀粉口服结肠靶向控释薄膜包衣材料及其制备方法和制备包衣材料的应用
WO2008028193A2 (en) * 2006-09-01 2008-03-06 Pharmion Corporation Colon-targeted oral formulations of cytidine analogs
US8853386B2 (en) 2006-12-18 2014-10-07 Celanese Acetate Llc Starch esters, methods of making same, and articles made therefrom
EP2179727B1 (en) * 2008-10-27 2013-05-29 Roquette Freres Water insoluble polymer: modified starch derivative-based film coatings for colon targeting

Also Published As

Publication number Publication date
JP2013525410A (ja) 2013-06-20
EP2563342B1 (en) 2016-04-20
US20130078289A1 (en) 2013-03-28
WO2011135055A1 (en) 2011-11-03
EP2386297A1 (en) 2011-11-16
KR20130072203A (ko) 2013-07-01
RU2012150803A (ru) 2014-06-10
JP5875196B2 (ja) 2016-03-02
EP2563342A1 (en) 2013-03-06
BR112012027447A2 (pt) 2016-07-19
CN102883714B (zh) 2016-04-13
CN102883714A (zh) 2013-01-16
CA2796955A1 (en) 2011-11-03
BR112012027447B1 (pt) 2021-06-01
MX2012012557A (es) 2012-11-23

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