MX2024008637A - Métodos para mejorar la resolución de proteínas heterodiméricas a partir de impurezas mediante el uso de cromatografía de afinidad. - Google Patents
Métodos para mejorar la resolución de proteínas heterodiméricas a partir de impurezas mediante el uso de cromatografía de afinidad.Info
- Publication number
- MX2024008637A MX2024008637A MX2024008637A MX2024008637A MX2024008637A MX 2024008637 A MX2024008637 A MX 2024008637A MX 2024008637 A MX2024008637 A MX 2024008637A MX 2024008637 A MX2024008637 A MX 2024008637A MX 2024008637 A MX2024008637 A MX 2024008637A
- Authority
- MX
- Mexico
- Prior art keywords
- impurities
- methods
- affinity chromatography
- improving resolution
- heterodimeric proteins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3804—Affinity chromatography
- B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263298745P | 2022-01-12 | 2022-01-12 | |
| US202263430477P | 2022-12-06 | 2022-12-06 | |
| PCT/US2023/010594 WO2023137062A1 (en) | 2022-01-12 | 2023-01-11 | Methods for improving resolution of heterodimeric proteins from impurities using affinity chromatography |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2024008637A true MX2024008637A (es) | 2024-08-27 |
Family
ID=85382626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2024008637A MX2024008637A (es) | 2022-01-12 | 2023-01-11 | Métodos para mejorar la resolución de proteínas heterodiméricas a partir de impurezas mediante el uso de cromatografía de afinidad. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230242579A1 (enExample) |
| EP (1) | EP4463463A1 (enExample) |
| JP (1) | JP2025502157A (enExample) |
| KR (1) | KR20240132357A (enExample) |
| AU (1) | AU2023207604A1 (enExample) |
| CA (1) | CA3242938A1 (enExample) |
| IL (1) | IL314032A (enExample) |
| MX (1) | MX2024008637A (enExample) |
| TW (1) | TW202337900A (enExample) |
| WO (1) | WO2023137062A1 (enExample) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI507525B (zh) | 2009-06-26 | 2015-11-11 | Regeneron Pharma | 具天然免疫球蛋白形式之易分離的雙專一性抗體 |
| EP3041593B1 (en) * | 2013-09-05 | 2025-01-29 | F. Hoffmann-La Roche AG | Method of cleaning a chromatography material for its reuse |
| GB201711481D0 (en) * | 2017-07-17 | 2017-08-30 | Ucb Biopharma Sprl | Protein purification |
| EP3956046A1 (en) * | 2019-04-17 | 2022-02-23 | Bristol-Myers Squibb Company | Methods for regenerating chromatography resins |
-
2023
- 2023-01-10 TW TW112101014A patent/TW202337900A/zh unknown
- 2023-01-11 WO PCT/US2023/010594 patent/WO2023137062A1/en not_active Ceased
- 2023-01-11 AU AU2023207604A patent/AU2023207604A1/en active Pending
- 2023-01-11 CA CA3242938A patent/CA3242938A1/en active Pending
- 2023-01-11 IL IL314032A patent/IL314032A/en unknown
- 2023-01-11 JP JP2024541632A patent/JP2025502157A/ja active Pending
- 2023-01-11 US US18/095,839 patent/US20230242579A1/en active Pending
- 2023-01-11 MX MX2024008637A patent/MX2024008637A/es unknown
- 2023-01-11 EP EP23707515.5A patent/EP4463463A1/en active Pending
- 2023-01-11 KR KR1020247026326A patent/KR20240132357A/ko active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4463463A1 (en) | 2024-11-20 |
| WO2023137062A1 (en) | 2023-07-20 |
| CA3242938A1 (en) | 2023-07-20 |
| US20230242579A1 (en) | 2023-08-03 |
| AU2023207604A1 (en) | 2024-07-25 |
| JP2025502157A (ja) | 2025-01-24 |
| TW202337900A (zh) | 2023-10-01 |
| IL314032A (en) | 2024-09-01 |
| KR20240132357A (ko) | 2024-09-03 |
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