MX2024001415A - Anticuerpos anti-cd36 y su uso para tratar el cancer. - Google Patents
Anticuerpos anti-cd36 y su uso para tratar el cancer.Info
- Publication number
- MX2024001415A MX2024001415A MX2024001415A MX2024001415A MX2024001415A MX 2024001415 A MX2024001415 A MX 2024001415A MX 2024001415 A MX2024001415 A MX 2024001415A MX 2024001415 A MX2024001415 A MX 2024001415A MX 2024001415 A MX2024001415 A MX 2024001415A
- Authority
- MX
- Mexico
- Prior art keywords
- antibodies
- treat cancer
- cancer
- targeting
- relates
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 201000011510 cancer Diseases 0.000 title abstract 4
- 102000049320 CD36 Human genes 0.000 abstract 3
- 108010045374 CD36 Antigens Proteins 0.000 abstract 3
- 230000008685 targeting Effects 0.000 abstract 2
- 206010027476 Metastases Diseases 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 208000037819 metastatic cancer Diseases 0.000 abstract 1
- 208000011575 metastatic malignant neoplasm Diseases 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/72—Increased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La invención reivindicada se refiere al tratamiento del cáncer que se dirige al CD36, un receptor de ácidos grasos. La invención reivindicada también se refiere al tratamiento de metástasis de cáncer dirigiéndose a CD36. La invención implica el uso de anticuerpos anti-CD36 como bloqueadores o inhibidores de la actividad de CD36 para tratar o prevenir el cáncer y/o el cáncer metastásico en un sujeto.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202163227806P | 2021-07-30 | 2021-07-30 | |
PCT/IB2022/057098 WO2023007472A1 (en) | 2021-07-30 | 2022-07-29 | Anti-cd36 antibodies and their use to treat cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2024001415A true MX2024001415A (es) | 2024-02-27 |
Family
ID=82799869
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2024001415A MX2024001415A (es) | 2021-07-30 | 2022-07-29 | Anticuerpos anti-cd36 y su uso para tratar el cancer. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP4377344A1 (es) |
JP (1) | JP2024529502A (es) |
KR (1) | KR20240042476A (es) |
CN (1) | CN118488964A (es) |
AU (1) | AU2022320051A1 (es) |
CA (1) | CA3226281A1 (es) |
IL (1) | IL309934A (es) |
MX (1) | MX2024001415A (es) |
WO (1) | WO2023007472A1 (es) |
Family Cites Families (77)
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BR112022014962A2 (pt) * | 2020-01-30 | 2022-09-20 | Ona Therapeutics S L | Terapia de combinação para tratamento de câncer e metástase de câncer |
EP4114445A1 (en) * | 2020-03-06 | 2023-01-11 | Ona Therapeutics S.L. | Anti-cd36 antibodies and their use to treat cancer |
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-
2022
- 2022-07-29 WO PCT/IB2022/057098 patent/WO2023007472A1/en active Application Filing
- 2022-07-29 MX MX2024001415A patent/MX2024001415A/es unknown
- 2022-07-29 AU AU2022320051A patent/AU2022320051A1/en active Pending
- 2022-07-29 JP JP2024505456A patent/JP2024529502A/ja active Pending
- 2022-07-29 CN CN202280066470.0A patent/CN118488964A/zh active Pending
- 2022-07-29 EP EP22751171.4A patent/EP4377344A1/en active Pending
- 2022-07-29 CA CA3226281A patent/CA3226281A1/en active Pending
- 2022-07-29 KR KR1020247006855A patent/KR20240042476A/ko unknown
- 2022-07-29 IL IL309934A patent/IL309934A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN118488964A (zh) | 2024-08-13 |
AU2022320051A1 (en) | 2024-01-25 |
CA3226281A1 (en) | 2023-02-02 |
EP4377344A1 (en) | 2024-06-05 |
WO2023007472A1 (en) | 2023-02-02 |
KR20240042476A (ko) | 2024-04-02 |
JP2024529502A (ja) | 2024-08-06 |
IL309934A (en) | 2024-03-01 |
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