MX2023006460A - Proteasa dependiente de atp mutante y procedimiento para la produccion de l-aminoacidos mediante el uso de la misma. - Google Patents

Proteasa dependiente de atp mutante y procedimiento para la produccion de l-aminoacidos mediante el uso de la misma.

Info

Publication number
MX2023006460A
MX2023006460A MX2023006460A MX2023006460A MX2023006460A MX 2023006460 A MX2023006460 A MX 2023006460A MX 2023006460 A MX2023006460 A MX 2023006460A MX 2023006460 A MX2023006460 A MX 2023006460A MX 2023006460 A MX2023006460 A MX 2023006460A
Authority
MX
Mexico
Prior art keywords
amino acid
producing
branched
chain amino
dependent protease
Prior art date
Application number
MX2023006460A
Other languages
English (en)
Inventor
Hyung Joon Kim
Jee Yeon Bae
Byoung Hoon Yoon
Seon Hye Kim
Kyungrim Kim
Sun Hyoung Choi
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of MX2023006460A publication Critical patent/MX2023006460A/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/06Alanine; Leucine; Isoleucine; Serine; Homoserine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21092Endopeptidase Clp (3.4.21.92)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15Corynebacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se proporciona una variante de proteasa dependiente de ATP y un procedimiento para la producción de L-aminoácidos mediante el uso de la misma.
MX2023006460A 2020-12-11 2021-07-12 Proteasa dependiente de atp mutante y procedimiento para la produccion de l-aminoacidos mediante el uso de la misma. MX2023006460A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20200173802 2020-12-11
PCT/KR2021/008881 WO2022124511A1 (ko) 2020-12-11 2021-07-12 변이형 atp-의존적 프로테아제 및 이를 이용한 l-아미노산의 생산 방법

Publications (1)

Publication Number Publication Date
MX2023006460A true MX2023006460A (es) 2023-06-15

Family

ID=81974668

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023006460A MX2023006460A (es) 2020-12-11 2021-07-12 Proteasa dependiente de atp mutante y procedimiento para la produccion de l-aminoacidos mediante el uso de la misma.

Country Status (8)

Country Link
US (1) US20240002827A1 (es)
EP (1) EP4242315A4 (es)
JP (1) JP2023551275A (es)
KR (1) KR20220083557A (es)
CN (1) CN117377757A (es)
CA (1) CA3199126A1 (es)
MX (1) MX2023006460A (es)
WO (1) WO2022124511A1 (es)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002020574A1 (en) * 2000-09-09 2002-03-14 Degussa Ag Nucleotide sequences which code for the clpc gene
EP2066782A4 (en) 2006-09-15 2010-02-03 Cj Cheiljedang Corp CORYNEBACTERIA WITH IMPROVED L-LYSINE PRODUCTIVITY AND METHOD FOR THE PREPARATION OF L-LYSINE THEREWITH
CN101335789A (zh) 2007-06-28 2008-12-31 万德洪 及时通讯系统的一种扩展以及实现方法
KR101117022B1 (ko) 2011-08-16 2012-03-16 씨제이제일제당 (주) L-발린 생산능이 향상된 미생물 및 이를 이용한 l-발린 제조방법
US9925251B2 (en) * 2011-10-19 2018-03-27 President And Fellows Of Harvard College Treatments for Mycobacterium tuberculosis
EP3009504B1 (en) 2013-06-11 2020-12-02 Cj Cheiljedang Corporation Microorganism producing l-isoleucine and method for preparing l-isoleucine using the same
KR101585061B1 (ko) * 2014-04-16 2016-01-13 영남대학교 산학협력단 ClpC1 유전자 또는 ClpC2 유전자를 이용하여 식물체의 유리 아미노산 함량을 증가시키는 방법 및 그에 따른 식물체
KR101796830B1 (ko) 2015-08-25 2017-11-13 씨제이제일제당 (주) L-류신 생산능을 가지는 미생물 및 이를 이용한 l-류신의 제조방법
KR102011994B1 (ko) 2017-06-30 2019-08-20 씨제이제일제당 주식회사 신규한 아스파토키나제 변이체 및 이를 이용한 l-아미노산의 제조방법
CN108085287B (zh) * 2017-12-14 2021-08-24 江南大学 一种重组谷氨酸棒状杆菌、其制备方法及其应用

Also Published As

Publication number Publication date
US20240002827A1 (en) 2024-01-04
EP4242315A4 (en) 2024-04-03
EP4242315A1 (en) 2023-09-13
CA3199126A1 (en) 2022-06-16
KR20220083557A (ko) 2022-06-20
WO2022124511A1 (ko) 2022-06-16
CN117377757A (zh) 2024-01-09
JP2023551275A (ja) 2023-12-07

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