MX2023004964A - Agente terapéutico para enfermedades progresivas ocasionadas por el incremento en células t positivas a cd4 positivas a eomes. - Google Patents
Agente terapéutico para enfermedades progresivas ocasionadas por el incremento en células t positivas a cd4 positivas a eomes.Info
- Publication number
- MX2023004964A MX2023004964A MX2023004964A MX2023004964A MX2023004964A MX 2023004964 A MX2023004964 A MX 2023004964A MX 2023004964 A MX2023004964 A MX 2023004964A MX 2023004964 A MX2023004964 A MX 2023004964A MX 2023004964 A MX2023004964 A MX 2023004964A
- Authority
- MX
- Mexico
- Prior art keywords
- positive
- sup
- sub
- therapeutic agent
- eomes
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 3
- 229940124597 therapeutic agent Drugs 0.000 title abstract 3
- 101100445364 Mus musculus Eomes gene Proteins 0.000 title abstract 2
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 2
- 101100445365 Xenopus laevis eomes gene Proteins 0.000 title abstract 2
- 208000037821 progressive disease Diseases 0.000 title abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- WQZGKKKJIJFFOK-UHFFFAOYSA-N hexopyranose Chemical group OCC1OC(O)C(O)C(O)C1O WQZGKKKJIJFFOK-UHFFFAOYSA-N 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
La presente invención provee un agente terapéutico para enfermedades progresivas ocasionadas por un incremento en células T positivas a CD4 positivas a Eomes, que comprende un compuesto representado por la fórmula (I), o una sal del mismo, como ingrediente activo. En la fórmula, R1 es un residuo de aldopiranosa, R2 es un átomo de hidrógeno o un grupo hidroxi, R3 es -CH2-, -CH(OH)-CH2- o -CH=CH-, R4 es un átomo de hidrógeno o CH3, x es 0 a 35, y y y z son, cada uno, un número entero que satisface y + z = 0 a 3. Fórmula Química 1. (ver fórmula).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP2020/041603 WO2022097287A1 (ja) | 2020-11-06 | 2020-11-06 | Ｅｏｍｅｓ陽性ＣＤ４陽性Ｔ細胞の増加に起因する進行型疾患治療剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2023004964A true MX2023004964A (es) | 2023-06-29 |
Family
ID=81457653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023004964A MX2023004964A (es) | 2020-11-06 | 2020-11-06 | Agente terapéutico para enfermedades progresivas ocasionadas por el incremento en células t positivas a cd4 positivas a eomes. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230405033A1 (es) |
| JP (1) | JPWO2022097287A1 (es) |
| KR (1) | KR20230104903A (es) |
| AU (1) | AU2020475870A1 (es) |
| CA (1) | CA3200571A1 (es) |
| MX (1) | MX2023004964A (es) |
| WO (1) | WO2022097287A1 (es) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1297017B1 (en) * | 2000-06-19 | 2012-06-13 | Beth Israel Deaconess Medical Center | Compositions and methods of monoclonal and polyclonal antibodies specific for t cell subpopulations |
| JPWO2016002827A1 (ja) | 2014-07-01 | 2017-04-27 | 国立研究開発法人国立精神・神経医療研究センター | 進行型免疫性脱髄疾患治療剤 |
| WO2016114386A1 (ja) | 2015-01-15 | 2016-07-21 | 国立研究開発法人国立精神・神経医療研究センター | 進行型免疫性脱髄疾患治療剤 |
| JP7112735B2 (ja) | 2016-11-29 | 2022-08-04 | 国立研究開発法人国立精神・神経医療研究センター | 進行型免疫性脱髄疾患の予防、発症抑制又は治療剤 |
-
2020
- 2020-11-06 MX MX2023004964A patent/MX2023004964A/es unknown
- 2020-11-06 JP JP2022560611A patent/JPWO2022097287A1/ja active Pending
- 2020-11-06 KR KR1020237018323A patent/KR20230104903A/ko unknown
- 2020-11-06 AU AU2020475870A patent/AU2020475870A1/en active Pending
- 2020-11-06 WO PCT/JP2020/041603 patent/WO2022097287A1/ja active Application Filing
- 2020-11-06 CA CA3200571A patent/CA3200571A1/en active Pending
- 2020-11-06 US US18/034,784 patent/US20230405033A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20230405033A1 (en) | 2023-12-21 |
| AU2020475870A1 (en) | 2023-06-15 |
| KR20230104903A (ko) | 2023-07-11 |
| WO2022097287A1 (ja) | 2022-05-12 |
| JPWO2022097287A1 (es) | 2022-05-12 |
| CA3200571A1 (en) | 2022-05-12 |
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