MX2009010559A - Derivados de heteroarilo. - Google Patents
Derivados de heteroarilo.Info
- Publication number
- MX2009010559A MX2009010559A MX2009010559A MX2009010559A MX2009010559A MX 2009010559 A MX2009010559 A MX 2009010559A MX 2009010559 A MX2009010559 A MX 2009010559A MX 2009010559 A MX2009010559 A MX 2009010559A MX 2009010559 A MX2009010559 A MX 2009010559A
- Authority
- MX
- Mexico
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- general formula
- represents hydrogen
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
La presente invención se refiere a un compuesto representado por la fórmula [1] o una sal farmacéuticamente aceptable del mismo. (ver fórmula (1)) En la fórmula [1], cualquiera de X e Y es CH y el otro es oxígeno o azufre; R es hidrógeno, etcétera; Z es hidrógeno, etcétera; Ar es fenilo, etcétera; y n es 1 o 2 y m es 1 o 2, excluyendo los compuestos donde n y m son ambos 2. También se proporciona una composición farmacéutica que comprende el compuesto o una sal farmacéuticamente aceptable del mismo como un ingrediente activo. La composición es utilizable como un agente para la prevención o tratamiento de la depresión, trastorno de pánico, ansiedad, trastorno obsesivo-compulsivo, dolor crónico, fibromialgia, obesidad, incontinencia urinaria por estrés, vejiga hiperactiva, etcétera.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007094548 | 2007-03-30 | ||
JP2007146039 | 2007-05-31 | ||
PCT/JP2008/056217 WO2008120761A1 (ja) | 2007-03-30 | 2008-03-28 | ヘテロアリール誘導体 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009010559A true MX2009010559A (es) | 2009-10-22 |
Family
ID=39808341
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009010559A MX2009010559A (es) | 2007-03-30 | 2008-03-28 | Derivados de heteroarilo. |
Country Status (11)
Country | Link |
---|---|
US (1) | US8217031B2 (es) |
EP (1) | EP2141168A4 (es) |
JP (1) | JP5206669B2 (es) |
KR (1) | KR20090130094A (es) |
AU (1) | AU2008233587B2 (es) |
BR (1) | BRPI0809483A2 (es) |
CA (1) | CA2682377A1 (es) |
MX (1) | MX2009010559A (es) |
MY (1) | MY151072A (es) |
RU (1) | RU2009140095A (es) |
WO (1) | WO2008120761A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120095048A1 (en) * | 2009-02-20 | 2012-04-19 | Region Midt Jylland | Allosteric binding compounds |
US9309262B2 (en) | 2013-03-13 | 2016-04-12 | Abt Holding Company | Thienylindole azepines as serotonin 5-HT2C receptor ligands and uses thereof |
MX2016002974A (es) | 2013-09-09 | 2016-06-02 | Peloton Therapeutics Inc | Eteres de arilo y sus usos. |
WO2015095048A1 (en) | 2013-12-16 | 2015-06-25 | Peloton Therapeutics, Inc. | Cyclic sulfone and sulfoximine analogs and uses thereof |
WO2016145032A1 (en) | 2015-03-11 | 2016-09-15 | Peloton Therapeutics, Inc. | Compositions for use in treating pulmonary arterial hypertension |
WO2016144825A1 (en) * | 2015-03-11 | 2016-09-15 | Peloton Therapeutics, Inc. | Aromatic compounds and uses thereof |
WO2016144826A1 (en) | 2015-03-11 | 2016-09-15 | Peloton Therapeutics, Inc. | Substituted pyridines and uses thereof |
US10512626B2 (en) | 2015-03-11 | 2019-12-24 | Peloton Therapeautics, Inc. | Compositions for use in treating glioblastoma |
US10335388B2 (en) | 2015-04-17 | 2019-07-02 | Peloton Therapeutics, Inc. | Combination therapy of a HIF-2-alpha inhibitor and an immunotherapeutic agent and uses thereof |
US9796697B2 (en) | 2015-06-12 | 2017-10-24 | Peloton Therapeutics, Inc. | Tricyclic inhibitors of HIF-2-alpha and uses thereof |
WO2020148679A1 (en) * | 2019-01-17 | 2020-07-23 | ViiV Healthcare UK (No.4) Limited | Process for preparing fostemsavir |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2312246A1 (fr) | 1975-05-28 | 1976-12-24 | Parcor | Derives de la tetrahydro-4,5,6,7 thieno (3,2-c) pyridine, leur procede de preparation et leurs applications |
FR2312247A1 (fr) | 1975-05-30 | 1976-12-24 | Parcor | Derives de la thieno-pyridine, leur procede de preparation et leurs applications |
WO2006004931A2 (en) * | 2004-06-30 | 2006-01-12 | Athersys, Inc. | Substituted azepine derivatives as serotonin receptor modulators |
GB0500300D0 (en) | 2005-01-07 | 2005-02-16 | Ionix Pharmaceuticals Ltd | Chemical compositions |
-
2008
- 2008-03-28 US US12/593,566 patent/US8217031B2/en not_active Expired - Fee Related
- 2008-03-28 CA CA002682377A patent/CA2682377A1/en not_active Abandoned
- 2008-03-28 RU RU2009140095/04A patent/RU2009140095A/ru not_active Application Discontinuation
- 2008-03-28 KR KR1020097022819A patent/KR20090130094A/ko not_active Application Discontinuation
- 2008-03-28 AU AU2008233587A patent/AU2008233587B2/en not_active Ceased
- 2008-03-28 JP JP2009507542A patent/JP5206669B2/ja not_active Expired - Fee Related
- 2008-03-28 WO PCT/JP2008/056217 patent/WO2008120761A1/ja active Application Filing
- 2008-03-28 BR BRPI0809483-7A patent/BRPI0809483A2/pt not_active IP Right Cessation
- 2008-03-28 EP EP20080739335 patent/EP2141168A4/en not_active Withdrawn
- 2008-03-28 MY MYPI20094032 patent/MY151072A/en unknown
- 2008-03-28 MX MX2009010559A patent/MX2009010559A/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JPWO2008120761A1 (ja) | 2010-07-15 |
CA2682377A1 (en) | 2008-10-09 |
JP5206669B2 (ja) | 2013-06-12 |
RU2009140095A (ru) | 2011-05-10 |
WO2008120761A1 (ja) | 2008-10-09 |
US8217031B2 (en) | 2012-07-10 |
EP2141168A4 (en) | 2011-07-20 |
AU2008233587B2 (en) | 2012-05-17 |
MY151072A (en) | 2014-03-31 |
AU2008233587A1 (en) | 2008-10-09 |
EP2141168A1 (en) | 2010-01-06 |
KR20090130094A (ko) | 2009-12-17 |
BRPI0809483A2 (pt) | 2014-09-09 |
US20100048537A1 (en) | 2010-02-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |