MX2023004350A - Proceso para la obtencion de una solucion de alcaloide psicoactivo purificada. - Google Patents

Proceso para la obtencion de una solucion de alcaloide psicoactivo purificada.

Info

Publication number
MX2023004350A
MX2023004350A MX2023004350A MX2023004350A MX2023004350A MX 2023004350 A MX2023004350 A MX 2023004350A MX 2023004350 A MX2023004350 A MX 2023004350A MX 2023004350 A MX2023004350 A MX 2023004350A MX 2023004350 A MX2023004350 A MX 2023004350A
Authority
MX
Mexico
Prior art keywords
psychoactive
extract
purified
alkaloid
psychoactive alkaloid
Prior art date
Application number
MX2023004350A
Other languages
English (en)
Inventor
Benjamin Lightburn
Ryan Moss
Lisa Ranken
Original Assignee
Psilo Scient Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA3097246A external-priority patent/CA3097246C/en
Priority claimed from PCT/CA2021/050813 external-priority patent/WO2021253116A1/en
Application filed by Psilo Scient Ltd filed Critical Psilo Scient Ltd
Publication of MX2023004350A publication Critical patent/MX2023004350A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B01D15/362—Cation-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • B01D15/426—Specific type of solvent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a una fuente de alcaloide psicoactivo para obtener un extracto de alcaloide psicoactivo. La fuente puede ser hongos psicodélicos, animales o plantas o un extracto previo de los mismos. Los alcaloides psicoactivos del extracto se adsorben en un material adsorbente, del cual luego se eluyen para proporcionar una solución de alcaloide psicoactivo purificada. El proceso puede repetirse con diferentes materiales adsorbentes, diferentes valores de pH y diferentes disolventes de elución. Los sólidos presentes en el extracto se eliminan en varias etapas por filtración o centrifugación. La solución de alcaloide psicoactivo purificada puede luego concentrarse en una suspensión y luego estandarizarse agregando excipientes y evaporando el solvente. El extracto estandarizado resultante tiene una concentración específica de alcaloides psicoactivos.
MX2023004350A 2020-10-23 2021-10-23 Proceso para la obtencion de una solucion de alcaloide psicoactivo purificada. MX2023004350A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA3097246A CA3097246C (en) 2020-10-23 2020-10-23 Process for obtaining a purified psychoactive alkaloid solution
PCT/CA2021/050813 WO2021253116A1 (en) 2020-06-17 2021-06-14 Compositions comprising psychoactive compounds from psychoactive organisms
PCT/CA2021/051495 WO2022082320A1 (en) 2020-10-23 2021-10-23 Process for obtaining a purified psychoactive alkaloid solution

Publications (1)

Publication Number Publication Date
MX2023004350A true MX2023004350A (es) 2023-09-12

Family

ID=81291112

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023004350A MX2023004350A (es) 2020-10-23 2021-10-23 Proceso para la obtencion de una solucion de alcaloide psicoactivo purificada.

Country Status (4)

Country Link
EP (1) EP4161549A4 (es)
BR (1) BR112022025782A2 (es)
MX (1) MX2023004350A (es)
WO (1) WO2022082320A1 (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101491647A (zh) * 2007-04-18 2009-07-29 北京和润创新医药科技发展有限公司 一种从中药麦角提取液中分离麦角总生物碱的方法
JP2022529662A (ja) * 2019-04-26 2022-06-23 ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル 二重グリカン結合ａａｖ２．５ベクターのための方法および組成物
CA3124367C (en) * 2020-06-17 2022-04-26 Psilo Scientific Ltd. Aqueous extraction of psychoactive compounds from psilocybin fungus

Also Published As

Publication number Publication date
BR112022025782A2 (pt) 2024-01-30
EP4161549A1 (en) 2023-04-12
EP4161549A4 (en) 2023-11-29
WO2022082320A1 (en) 2022-04-28

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