MX2023000492A - Proceso para producir un rabdovirus purificado a partir de cultivo celular. - Google Patents
Proceso para producir un rabdovirus purificado a partir de cultivo celular.Info
- Publication number
- MX2023000492A MX2023000492A MX2023000492A MX2023000492A MX2023000492A MX 2023000492 A MX2023000492 A MX 2023000492A MX 2023000492 A MX2023000492 A MX 2023000492A MX 2023000492 A MX2023000492 A MX 2023000492A MX 2023000492 A MX2023000492 A MX 2023000492A
- Authority
- MX
- Mexico
- Prior art keywords
- rhabdovirus
- purified
- producing
- cell culture
- upstream
- Prior art date
Links
- 238000004113 cell culture Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 241000711975 Vesicular stomatitis virus Species 0.000 abstract 1
- 238000011143 downstream manufacturing Methods 0.000 abstract 1
- 230000000174 oncolytic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011144 upstream manufacturing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20221—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20241—Use of virus, viral particle or viral elements as a vector
- C12N2760/20244—Chimeric viral vector comprising heterologous viral elements for production of another viral vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20251—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20251—Methods of production or purification of viral material
- C12N2760/20252—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
La presente invención se refiere al campo del procesamiento corriente arriba y corriente abajo, y proporciona un proceso para producir un rabdovirus purificado a partir de un cultivo celular, preferentemente, un rabdovirus oncolítico purificado y, en particular, un virus de la estomatitis vesicular, que incluye composiciones farmacéuticas que comprenden el rabdovirus.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20185118 | 2020-07-10 | ||
PCT/EP2021/069091 WO2022008700A1 (en) | 2020-07-10 | 2021-07-09 | Process for producing a purified rhabdovirus from cell culture |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2023000492A true MX2023000492A (es) | 2023-02-13 |
Family
ID=71575102
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2023000492A MX2023000492A (es) | 2020-07-10 | 2021-07-09 | Proceso para producir un rabdovirus purificado a partir de cultivo celular. |
Country Status (13)
Country | Link |
---|---|
US (1) | US20220010286A1 (es) |
EP (1) | EP4179073A1 (es) |
JP (1) | JP2023532759A (es) |
KR (1) | KR20230035657A (es) |
CN (1) | CN116171322A (es) |
AU (1) | AU2021304892A1 (es) |
BR (1) | BR112022025251A2 (es) |
CA (1) | CA3187150A1 (es) |
CL (1) | CL2023000080A1 (es) |
IL (1) | IL299723A (es) |
MX (1) | MX2023000492A (es) |
TW (1) | TW202216992A (es) |
WO (1) | WO2022008700A1 (es) |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9716611D0 (en) * | 1997-08-07 | 1997-10-08 | Cantab Pharmaceuticals Res Ltd | Virus preparations and methods |
BR122019005271B1 (pt) * | 2002-12-13 | 2020-10-13 | Alphavax, Inc. | método para a preparação de partículas de replicon de alfavírus (arps) |
BRPI0710820A2 (pt) * | 2006-04-20 | 2011-08-23 | Wyeth Corp | processo para a purificação do vìrus da estomatite vesicular (vsv) do fluido de cultura celular de uma cultura de células de mamìferos infectada com vsv; vsv purificado de acordo com o processo; composição farmacêutica; e composição imunogênica |
DE102008050860A1 (de) * | 2008-10-08 | 2010-04-15 | Dorothee Von Laer | LCMV-GP-VSV-Pseudotypvektoren und tumorinfiltrierende Virenproduzentenzellen zur Therapie von Tumoren |
US20100143889A1 (en) * | 2008-12-02 | 2010-06-10 | Mayo Foundation For Medical Education And Research | Rhabdoviridae virus preparations |
WO2013106398A1 (en) * | 2012-01-09 | 2013-07-18 | Sanofi Pasteur Biologics, Llc | Purification of herpes virus |
CA3104392A1 (en) * | 2018-07-04 | 2020-01-09 | Probiogen Ag | Method for purifying an enveloped virus |
JP2021191232A (ja) * | 2018-08-09 | 2021-12-16 | 昭和電工株式会社 | ウイルス様粒子の精製法 |
TW202043466A (zh) * | 2019-01-25 | 2020-12-01 | 德商百靈佳殷格翰國際股份有限公司 | 編碼ccl21之重組棒狀病毒 |
-
2021
- 2021-07-09 CN CN202180048258.7A patent/CN116171322A/zh active Pending
- 2021-07-09 EP EP21740521.6A patent/EP4179073A1/en active Pending
- 2021-07-09 CA CA3187150A patent/CA3187150A1/en active Pending
- 2021-07-09 IL IL299723A patent/IL299723A/en unknown
- 2021-07-09 TW TW110125247A patent/TW202216992A/zh unknown
- 2021-07-09 WO PCT/EP2021/069091 patent/WO2022008700A1/en unknown
- 2021-07-09 US US17/371,159 patent/US20220010286A1/en active Pending
- 2021-07-09 KR KR1020237004820A patent/KR20230035657A/ko active Search and Examination
- 2021-07-09 AU AU2021304892A patent/AU2021304892A1/en active Pending
- 2021-07-09 JP JP2023500320A patent/JP2023532759A/ja active Pending
- 2021-07-09 MX MX2023000492A patent/MX2023000492A/es unknown
- 2021-07-09 BR BR112022025251A patent/BR112022025251A2/pt unknown
-
2023
- 2023-01-09 CL CL2023000080A patent/CL2023000080A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
CN116171322A (zh) | 2023-05-26 |
BR112022025251A2 (pt) | 2023-01-17 |
JP2023532759A (ja) | 2023-07-31 |
CA3187150A1 (en) | 2022-01-13 |
TW202216992A (zh) | 2022-05-01 |
US20220010286A1 (en) | 2022-01-13 |
IL299723A (en) | 2023-03-01 |
AU2021304892A1 (en) | 2023-01-19 |
CL2023000080A1 (es) | 2023-09-08 |
EP4179073A1 (en) | 2023-05-17 |
KR20230035657A (ko) | 2023-03-14 |
WO2022008700A1 (en) | 2022-01-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RU2013119415A (ru) | Способ получения поксвирусов и композиции поксвирусов | |
MY193820A (en) | Exhaust gas treatment system | |
MX2022010870A (es) | Composicion que comprende lactoferrina y cepas bacterianas probioticas para uso oral con accion antiviral. | |
MXPA02002772A (es) | Virus oncolitico. | |
JP2003510291A5 (es) | ||
BRPI0714495B8 (pt) | lentivírus deficiente para replicação recombinante pseudotipado | |
HRP20050690A2 (en) | Hiv inhibiting 1,2,4-triazines | |
MX2021009554A (es) | Produccion de virus en cultivos celulares. | |
EP2490751A4 (en) | METHOD AND SYSTEMS FOR PROVIDING ERYTHROCYTE PRODUCTS WITH REDUCED PLASMA | |
MX2021010145A (es) | Derivados de amida utiles en el tratamiento de una infeccion por vhb o de enfermedades inducidas por vhb. | |
MX2023000492A (es) | Proceso para producir un rabdovirus purificado a partir de cultivo celular. | |
WO2020035609A3 (en) | Immunogenic compositions and uses thereof | |
CY1110662T1 (el) | Απαλλαγμενοι απο πηκτωματα βλαστοι λιναριου και το παραπροϊον τους, καθως και η παραγωγη και η εφαρμογη τους | |
CN115386537A (zh) | 用于Vero细胞的化学限定培养基添加剂、及其在培养细胞和扩增病毒中的用途 | |
ZA202306360B (en) | Substituted pyridotriazine compounds and uses thereof | |
SA521422601B1 (ar) | فيروس ربدي ناتج عن عودة الارتباط الجيني يشفر ccl21 | |
TW200612833A (en) | Genetically purified gellan gum | |
MX2022009871A (es) | Compuestos tetraciclicos para tratar la infeccion por el virus de la inmunodeficiencia humana (vih). | |
IN2013MN01230A (es) | ||
CN115386536B (zh) | 用于培养Vero细胞的化学限定培养基、扩增病毒的方法和制备疫苗的方法 | |
MX2023010370A (es) | Vacuna del metapneumovirus humano. | |
MX346787B (es) | Sulfato de controitina similar al de tiburon y proceso para la preparacion del mismo. | |
SA522441579B1 (ar) | ترميز الفيروس الربدي ناتج عودة الارتباط الجيني لبروتين دمج شظية قابلة للتبلر لنطاق عنقود التمايز 80 خارج الخلايا | |
MX2021016005A (es) | Derivados de aminas terciarias y sus usos para tratar una infección vírica. | |
BR112021021672A2 (pt) | Método para otimizar o fluxo de gás para processos de fermentação paralelos, fermentação em série, e, fermentação |