MX2022011697A - Inhibidores de ciclofilina y usos de los mismos. - Google Patents
Inhibidores de ciclofilina y usos de los mismos.Info
- Publication number
- MX2022011697A MX2022011697A MX2022011697A MX2022011697A MX2022011697A MX 2022011697 A MX2022011697 A MX 2022011697A MX 2022011697 A MX2022011697 A MX 2022011697A MX 2022011697 A MX2022011697 A MX 2022011697A MX 2022011697 A MX2022011697 A MX 2022011697A
- Authority
- MX
- Mexico
- Prior art keywords
- cyclophilin inhibitors
- cyclophilin
- inhibitors
- organ
- disorders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Analytical Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2020081295 | 2020-03-26 | ||
| CN2021078391 | 2021-03-01 | ||
| PCT/CN2021/083013 WO2021190601A1 (en) | 2020-03-26 | 2021-03-25 | Cyclophilin inhibitors and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022011697A true MX2022011697A (es) | 2022-10-07 |
Family
ID=77891510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022011697A MX2022011697A (es) | 2020-03-26 | 2021-03-25 | Inhibidores de ciclofilina y usos de los mismos. |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20230174583A1 (https=) |
| EP (2) | EP4126905A4 (https=) |
| JP (2) | JP7761578B2 (https=) |
| KR (2) | KR20220158761A (https=) |
| CN (2) | CN115335389A (https=) |
| AU (1) | AU2021240762A1 (https=) |
| BR (1) | BR112022018929A2 (https=) |
| CA (2) | CA3172601A1 (https=) |
| IL (1) | IL296586B1 (https=) |
| MX (1) | MX2022011697A (https=) |
| WO (2) | WO2021190601A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111449050A (zh) * | 2019-01-20 | 2020-07-28 | 睿诺医疗科技（上海）有限公司 | 环孢菌素类似物及其用途 |
| AU2020363688A1 (en) | 2019-10-12 | 2022-04-21 | Farsight Medical Technology (Shanghai) Co., Ltd. | Treatment and prevention of nephrotoxin-induced kidney injuries |
| IL296586B1 (en) * | 2020-03-26 | 2026-04-01 | Farsight Medical Tech Shanghai Co Ltd | Cyclophilin inhibitors and their uses |
| AU2021256222A1 (en) | 2020-04-15 | 2022-10-06 | Farsight Medical Technology (Shanghai) Co., Ltd. | Prevention and treatment of organ injuries |
| GB202207348D0 (en) * | 2022-05-19 | 2022-07-06 | Cypralis Ltd | Macrocyclic compounds and uses thereof |
| WO2024183651A1 (en) * | 2023-03-03 | 2024-09-12 | Farsight Medical Technology (Shanghai) Co., Ltd. | Treatment and prevention of agent‐induced liver conditions or diseases |
| KR20260018851A (ko) * | 2023-06-02 | 2026-02-09 | 파사이트 메디컬 테크놀로지 (상하이) 컴퍼니 리미티드 | 사이클로필린 저해제 및 그 용도 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0194972B1 (en) | 1985-03-11 | 1992-07-29 | Sandoz Ag | Novel cyclosporins |
| FI111730B (fi) | 1990-11-02 | 2003-09-15 | Novartis Ag | Menetelmä ei-immunosuppressiivisen syklosporiinin valmistamiseksi |
| AU750245B2 (en) * | 1997-10-08 | 2002-07-11 | Aurinia Phamaceuticals Inc. | Deuterated cyclosporine analogs and their use as immunomodulating agents |
| CN1205220C (zh) | 1998-06-12 | 2005-06-08 | 斯－凯穆公司 | 新颖的环孢菌素 |
| US6809077B2 (en) | 2001-10-12 | 2004-10-26 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogs for the treatment of autoimmune diseases |
| CN100344648C (zh) | 2001-10-19 | 2007-10-24 | 伊索泰克尼卡股份有限公司 | 环孢菌素类似物混合物及其在制备免疫调节剂中的用途 |
| US7538084B2 (en) | 2003-03-17 | 2009-05-26 | Amr Technology, Inc. | Cyclosporins |
| SI1802650T1 (sl) | 2004-10-01 | 2012-03-30 | Scynexis Inc | Eter in tioeter substituirani ciklosporinski derivati za zdravljenje in preventivo pred infekcijami s hepatitisom c |
| ZA200703157B (en) * | 2004-10-01 | 2008-08-27 | Scynexis Inc | 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection |
| EP2023918B1 (en) * | 2006-05-19 | 2011-03-23 | Scynexis, Inc. | Cyclosporins for the treatment and prevention of ocular disorders |
| WO2008143996A1 (en) * | 2007-05-18 | 2008-11-27 | Scynexis, Inc. | New chemical processes |
| AU2009276241A1 (en) | 2008-07-30 | 2010-02-04 | Ciclofilin Pharmaceuticals Corp. | Nonimmunosuppressive cyclosporine analogue molecules |
| KR20110111321A (ko) * | 2009-01-30 | 2011-10-10 | 이난타 파마슈티칼스, 인코포레이티드 | Ｃ형 간염을 예방하거나 치료하기 위한 사이클로스포린 유사체 |
| US8481483B2 (en) | 2009-02-19 | 2013-07-09 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
| WO2011082289A1 (en) * | 2009-12-30 | 2011-07-07 | Scynexis Inc. | Cyclosporine analogues |
| WO2012009715A2 (en) * | 2010-07-16 | 2012-01-19 | S&T Global Inc. | Novel cyclosporin derivatives for the treatment and prevention of a viral infection |
| US9890198B2 (en) * | 2010-12-03 | 2018-02-13 | S&T Global Inc. | Cyclosporin derivatives and uses thereof |
| BR112013014890B1 (pt) | 2010-12-15 | 2023-10-24 | Contravir Pharmaceuticals, Inc | Composto análogo de moléculas pertencentes à família ciclosporina, composição farmacêutica compreendendo o mesmo, uso terapêutico ou profilático do referido composto e processos para a preparação dos mesmos |
| DE102011111991A1 (de) * | 2011-08-30 | 2013-02-28 | Lead Discovery Center Gmbh | Neue Cyclosporin-Derivate |
| GB201217560D0 (en) | 2012-10-02 | 2012-11-14 | Mitopharm Ltd | Novel cyclic depsipeptide compounds and their uses |
| US20140212381A1 (en) * | 2012-10-19 | 2014-07-31 | Scynexis, Inc. | Macrocycles |
| GB201222455D0 (en) * | 2012-12-13 | 2013-01-30 | Perioc Ltd | Novel pharmaceutical formulations and their use in the treatment of periodontaldisease |
| GB201414806D0 (en) | 2014-08-20 | 2014-10-01 | Ucl Business Plc | Cyclosporin conjugates |
| WO2017004304A1 (en) * | 2015-06-30 | 2017-01-05 | Cypralis Limited | Novel macrocycles |
| CN106902346A (zh) * | 2015-12-23 | 2017-06-30 | 中美华世通生物医药科技（武汉）有限公司 | 药物组合物及其制药用途 |
| CN106902347A (zh) * | 2015-12-23 | 2017-06-30 | 中美华世通生物医药科技（武汉）有限公司 | 亲环孢素抑制剂的用途 |
| CN118324867A (zh) * | 2016-05-17 | 2024-07-12 | 美国科技环球有限公司 | 新型环孢菌素衍生物及其用途 |
| GB201711749D0 (en) * | 2017-07-21 | 2017-09-06 | Cypralis Ltd | Cyclosporin analogues and uses thereof |
| WO2020037530A1 (en) * | 2018-08-22 | 2020-02-27 | Waterstone Pharmaceuticals (Wuhan) Co., Ltd. | Crystalline form of compound and uses thereof in medicine |
| CN111449050A (zh) * | 2019-01-20 | 2020-07-28 | 睿诺医疗科技（上海）有限公司 | 环孢菌素类似物及其用途 |
| IL296586B1 (en) * | 2020-03-26 | 2026-04-01 | Farsight Medical Tech Shanghai Co Ltd | Cyclophilin inhibitors and their uses |
-
2021
- 2021-03-24 IL IL296586A patent/IL296586B1/en unknown
- 2021-03-25 KR KR1020227036440A patent/KR20220158761A/ko active Pending
- 2021-03-25 JP JP2022556477A patent/JP7761578B2/ja active Active
- 2021-03-25 CN CN202180023394.0A patent/CN115335389A/zh active Pending
- 2021-03-25 EP EP21776894.4A patent/EP4126905A4/en active Pending
- 2021-03-25 KR KR1020227036439A patent/KR20220158760A/ko active Pending
- 2021-03-25 WO PCT/CN2021/083013 patent/WO2021190601A1/en not_active Ceased
- 2021-03-25 BR BR112022018929A patent/BR112022018929A2/pt unknown
- 2021-03-25 EP EP21776582.5A patent/EP4126904A4/en active Pending
- 2021-03-25 JP JP2022556478A patent/JP7776435B2/ja active Active
- 2021-03-25 CN CN202180023172.9A patent/CN115298199A/zh active Pending
- 2021-03-25 WO PCT/CN2021/083016 patent/WO2021190604A1/en not_active Ceased
- 2021-03-25 MX MX2022011697A patent/MX2022011697A/es unknown
- 2021-03-25 CA CA3172601A patent/CA3172601A1/en active Pending
- 2021-03-25 CA CA3172535A patent/CA3172535A1/en active Pending
- 2021-03-25 AU AU2021240762A patent/AU2021240762A1/en active Pending
- 2021-03-25 US US17/906,348 patent/US20230174583A1/en active Pending
-
2022
- 2022-09-16 US US17/946,071 patent/US12060440B2/en active Active
-
2024
- 2024-06-26 US US18/754,189 patent/US12522634B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP4126905A1 (en) | 2023-02-08 |
| JP2023518777A (ja) | 2023-05-08 |
| TW202144379A (zh) | 2021-12-01 |
| US20230174583A1 (en) | 2023-06-08 |
| JP7776435B2 (ja) | 2025-11-26 |
| US20240352074A1 (en) | 2024-10-24 |
| EP4126904A4 (en) | 2024-05-29 |
| IL296586A (en) | 2022-11-01 |
| CN115335389A (zh) | 2022-11-11 |
| IL296586B1 (en) | 2026-04-01 |
| JP7761578B2 (ja) | 2025-10-28 |
| CN115298199A (zh) | 2022-11-04 |
| US20230110497A1 (en) | 2023-04-13 |
| US12522634B2 (en) | 2026-01-13 |
| KR20220158760A (ko) | 2022-12-01 |
| BR112022018929A2 (pt) | 2022-12-06 |
| JP2023518776A (ja) | 2023-05-08 |
| AU2021240762A1 (en) | 2022-10-06 |
| CA3172601A1 (en) | 2021-09-30 |
| WO2021190601A1 (en) | 2021-09-30 |
| EP4126904A1 (en) | 2023-02-08 |
| CA3172535A1 (en) | 2021-09-30 |
| WO2021190604A1 (en) | 2021-09-30 |
| US12060440B2 (en) | 2024-08-13 |
| KR20220158761A (ko) | 2022-12-01 |
| EP4126905A4 (en) | 2024-05-29 |
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