MX2022011362A - Cebador en bucle y metodo de bucle-de-bucle para detectar acido nucleico objetivo. - Google Patents

Cebador en bucle y metodo de bucle-de-bucle para detectar acido nucleico objetivo.

Info

Publication number
MX2022011362A
MX2022011362A MX2022011362A MX2022011362A MX2022011362A MX 2022011362 A MX2022011362 A MX 2022011362A MX 2022011362 A MX2022011362 A MX 2022011362A MX 2022011362 A MX2022011362 A MX 2022011362A MX 2022011362 A MX2022011362 A MX 2022011362A
Authority
MX
Mexico
Prior art keywords
loop
nucleic acid
target nucleic
detecting target
looped primer
Prior art date
Application number
MX2022011362A
Other languages
English (en)
Spanish (es)
Inventor
Cameron Scott Ball
Original Assignee
Uh Oh Labs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uh Oh Labs Inc filed Critical Uh Oh Labs Inc
Publication of MX2022011362A publication Critical patent/MX2022011362A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6853Nucleic acid amplification reactions using modified primers or templates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6818Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6825Nucleic acid detection involving sensors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/30Oligonucleotides characterised by their secondary structure
    • C12Q2525/301Hairpin oligonucleotides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00Reactions demanding special reaction conditions
    • C12Q2527/107Temperature of melting, i.e. Tm
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/107Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/10Detection mode being characterised by the assay principle
    • C12Q2565/101Interaction between at least two labels

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
MX2022011362A 2020-03-13 2021-03-12 Cebador en bucle y metodo de bucle-de-bucle para detectar acido nucleico objetivo. MX2022011362A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202062989140P 2020-03-13 2020-03-13
PCT/US2021/022192 WO2021183941A1 (en) 2020-03-13 2021-03-12 Looped primer and loop-de-loop method for detecting target nucleic acid

Publications (1)

Publication Number Publication Date
MX2022011362A true MX2022011362A (es) 2023-02-22

Family

ID=77664496

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022011362A MX2022011362A (es) 2020-03-13 2021-03-12 Cebador en bucle y metodo de bucle-de-bucle para detectar acido nucleico objetivo.

Country Status (9)

Country Link
US (3) US11377683B2 (https=)
EP (1) EP4118205A4 (https=)
JP (2) JP7634551B2 (https=)
KR (2) KR102814480B1 (https=)
CN (1) CN115867653A (https=)
AU (1) AU2021236383A1 (https=)
CA (1) CA3174493A1 (https=)
MX (1) MX2022011362A (https=)
WO (1) WO2021183941A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022018741A1 (en) * 2020-07-23 2022-01-27 Indian Institute Of Technology, Kharagpur A point of care (poc) device for nucleic acid based testing and method thereof
US20240376528A1 (en) * 2021-09-13 2024-11-14 Uh-Oh Labs Inc. Looped Primer with Various Internal Modifications and Loop-De-Loop Method for Target Detection
WO2023106866A1 (ko) * 2021-12-10 2023-06-15 주식회사 씨젠 단일 가닥 상호작용적 이중 표지 시스템을 포함하는 태그된 루프프라이머 및 이를 이용한 핵산 등온 증폭 방법
CN118207310A (zh) * 2022-12-08 2024-06-18 广东润鹏生物技术有限公司 一种可剪切环状引物及其试剂盒与扩增方法
GB202408733D0 (en) * 2024-06-18 2024-07-31 Univ Oxford Innovation Ltd Rapid nucleic acid amplification method

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5866336A (en) * 1996-07-16 1999-02-02 Oncor, Inc. Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US6117635A (en) * 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US6365346B1 (en) * 1998-02-18 2002-04-02 Dade Behring Inc. Quantitative determination of nucleic acid amplification products
GB9812768D0 (en) 1998-06-13 1998-08-12 Zeneca Ltd Methods
EP1020534B2 (en) 1998-11-09 2011-01-05 Eiken Kagaku Kabushiki Kaisha Process for synthesizing nucleic acid
US20030148303A1 (en) * 2000-09-19 2003-08-07 Nadeau James G. Universal probes and methods for detection of nucleic acids
ES2327712T3 (es) 2000-09-19 2009-11-03 Eiken Kagaku Kabushiki Kaisha Procedimiento para sintetizar polinucleotidos.
US20030165859A1 (en) 2001-10-23 2003-09-04 Invitrogen Corporation Primers and methods for the detection and discrimination of nucleic acids
US9487807B2 (en) * 2010-12-27 2016-11-08 Ibis Biosciences, Inc. Compositions and methods for producing single-stranded circular DNA
US10876160B2 (en) 2011-10-31 2020-12-29 Eiken Kagaku Kabushiki Kaisha Method for detecting target nucleic acid
US20160289752A1 (en) 2015-03-31 2016-10-06 Transponics Method for the Isothermic Amplification of Nucleic Acid and SNP Detection
CN104694662A (zh) * 2015-04-03 2015-06-10 杜文红 核酸等温扩增反应检测方法及应用该方法的检测试剂盒
ITUB20159332A1 (it) * 2015-12-22 2017-06-22 Diasorin S P A Procedimento di rivelazione in fluorescenza dell?amplificazione isotermica mediata da loop (LAMP) di un acido nucleico bersaglio, relativi oligonucleotidi e kit.

Also Published As

Publication number Publication date
JP2023518217A (ja) 2023-04-28
KR20250090353A (ko) 2025-06-19
JP2025072582A (ja) 2025-05-09
US12559793B2 (en) 2026-02-24
BR112022018015A2 (pt) 2022-12-06
US20210285039A1 (en) 2021-09-16
US11753679B2 (en) 2023-09-12
CN115867653A (zh) 2023-03-28
KR102814480B1 (ko) 2025-05-29
EP4118205A4 (en) 2024-04-17
JP7634551B2 (ja) 2025-02-21
AU2021236383A1 (en) 2022-09-22
CA3174493A1 (en) 2021-09-16
KR20230012467A (ko) 2023-01-26
EP4118205A1 (en) 2023-01-18
US11377683B2 (en) 2022-07-05
US20240011083A1 (en) 2024-01-11
WO2021183941A1 (en) 2021-09-16
US20220170086A1 (en) 2022-06-02

Similar Documents

Publication Publication Date Title
MX2022011362A (es) Cebador en bucle y metodo de bucle-de-bucle para detectar acido nucleico objetivo.
MX2021000946A (es) Metodo de deteccion de acido nucleico.
PH12020500103A1 (en) Use of cas protein, method for detecting target nucleic acid molecule, and kit
EP4328303A3 (en) Novel use
WO2020106630A9 (en) Methods for detecting and sequencing a target nucleic acid
EP4296373A3 (en) Normalization controls for managing low sample inputs in next generation sequencing
WO2014138119A3 (en) Method and kit for characterizing microorganisms
MX2017014821A (es) Método para determinar la secuencia de un acido nucleico usando luminiscencia resuelta por tiempo.
PH12022552313A1 (en) Pretreatment method, pretreatment solution, kit for virus nucleic acid detection, and use thereof
NZ723570A (en) Compositions and methods for quantifying a nucleic acid sequence in a sample
BR112012019396A2 (pt) método e kit para amplificar um ácido nucleico.
GB0317343D0 (en) Polynucleotide sequencing
EP4428528A3 (en) Labeled nucleotide compositions and methods for nucleic acid sequencing
SG155995A1 (en) Genomic assay
WO2020127908A3 (en) Method of detecting infection with pathogens causing tuberculosis
CA3010199A1 (en) Method of direct target sequencing using nuclease protection
ZA202205645B (en) Identification and analysis of microbial samples by rapid incubation and nucleic acid enrichment
WO2005001034A3 (en) Rna-exit-channel: target and method for inhibition of bacterial rna polymerase
PL446241A1 (pl) Metoda wykrywania zmian sekwencji nukleotydowej z wykorzystanym techniki izotermalnejamplifikacji kwasów nukleinowych, zestaw starterów oraz skład mieszaniny reakcyjnej do wykrywania wybranych wariantów genetycznych
PL418391A1 (pl) Dwie pary oligonukleotydowych starterów do wykrywania genu karłowatości dw9 i sposób wykrywania recesywnego genu karłowatości dw9 w roślinach żyta (Secale cereale L.)
PL426258A1 (pl) Para oligonukleotydowych starterów do wykrywania genu karłowatości ct2 i sposób wykrywania recesywnego genu karłowatości ct2 w roślinach żyta (Secale cereale L.)
GB2608474B (en) Kit, apparatus and method for a portable nucleic acid assay
GB202203292D0 (en) Nucleic acid amplification, kits, methods, and uses
GB202111615D0 (en) Nucleic acid amplification, kits, methods, and uses
GB202103315D0 (en) Nucleic acid amplification, kits, methods, and uses