MX2022010461A - Metodos para expandir linfocitos t para el tratamiento de cancer y neoplasias malignas asociadas. - Google Patents

Metodos para expandir linfocitos t para el tratamiento de cancer y neoplasias malignas asociadas.

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Publication number
MX2022010461A
MX2022010461A MX2022010461A MX2022010461A MX2022010461A MX 2022010461 A MX2022010461 A MX 2022010461A MX 2022010461 A MX2022010461 A MX 2022010461A MX 2022010461 A MX2022010461 A MX 2022010461A MX 2022010461 A MX2022010461 A MX 2022010461A
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Mexico
Prior art keywords
cells
expanding
cancer
treatment
methods
Prior art date
Application number
MX2022010461A
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English (en)
Inventor
Steffen Walter
Melinda Mata
Mamta Kalra
Ali Mohamed
Yannick Bulliard
Original Assignee
Immatics Us Inc
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Publication date
Application filed by Immatics Us Inc filed Critical Immatics Us Inc
Publication of MX2022010461A publication Critical patent/MX2022010461A/es

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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
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Abstract

Un método in vitro para expandir los linfocitos T ?d incluye aislar los linfocitos T ?d de una muestra de sangre de un sujeto humano, activar los linfocitos T ?d aislados en presencia de un aminobifosfonato y/o una célula alimentadora y al menos una citocina, expandir los linfocitos T ?d, y opcionalmente reestimular los linfocitos T ?d expandidos.
MX2022010461A 2020-02-24 2021-02-23 Metodos para expandir linfocitos t para el tratamiento de cancer y neoplasias malignas asociadas. MX2022010461A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202062980844P 2020-02-24 2020-02-24
US202063038008P 2020-06-11 2020-06-11
US202063082881P 2020-09-24 2020-09-24
PCT/US2021/019252 WO2021173560A1 (en) 2020-02-24 2021-02-23 Methods for expanding t cells for the treatment of cancer and related malignancies

Publications (1)

Publication Number Publication Date
MX2022010461A true MX2022010461A (es) 2022-12-13

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MX2022010461A MX2022010461A (es) 2020-02-24 2021-02-23 Metodos para expandir linfocitos t para el tratamiento de cancer y neoplasias malignas asociadas.

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EP (1) EP4110901A1 (es)
JP (1) JP2023515131A (es)
KR (1) KR20230012465A (es)
CN (1) CN115427554A (es)
AU (1) AU2021225817A1 (es)
BR (1) BR112022016909A2 (es)
CA (1) CA3168729A1 (es)
IL (1) IL295891A (es)
MX (1) MX2022010461A (es)
TW (1) TW202146645A (es)
WO (1) WO2021173560A1 (es)

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DE102017106305A1 (de) 2017-03-23 2018-09-27 Immatics Biotechnologies Gmbh Neue T-Zellrezeptoren und deren Verwendung in Immuntherapien gegen prame-positive Krebsarten
US11236145B2 (en) 2017-03-23 2022-02-01 Immatics Biotechnologies Gmbh T cell receptors and immune therapy using the same against PRAME positive cancers
DE102017114737A1 (de) 2017-06-30 2019-01-03 Immatics Biotechnologies Gmbh Neue T-Zellrezeptoren und deren Verwendung in Immuntherapie
PE20200614A1 (es) 2017-07-14 2020-03-11 Immatics Biotechnologies Gmbh Molecula de polipeptido con especificidad dual mejorada
GB201715918D0 (en) * 2017-09-29 2017-11-15 Tc Biopharm Ltd Modified CAR-T
WO2019086665A1 (en) 2017-11-06 2019-05-09 Immatics Biotechnologies Gmbh Novel engineered t cell receptors and immune therapy using the same
DE102017127984B4 (de) * 2017-11-27 2019-12-05 Immatics US, Inc. Verfahren für die Vermehrung und Aktivierung von γδ-T-Zellen
DE102018122546B3 (de) 2018-09-14 2019-12-05 Immatics Biotechnologies Gmbh Verfahren zum Hochdurchsatz-Peptid-MHC-Affinitätsscreening für TCR-Liganden
CN109234236A (zh) * 2018-09-29 2019-01-18 吉林大学第医院 一种嵌合抗原受体γδT细胞的制备方法
US20200384028A1 (en) 2019-06-06 2020-12-10 Immatics Biotechnologies Gmbh Sorting with counter selection using sequence similar peptides

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