MX2022007162A - Forma de dosificacion que comprende un agente alcalino y una capa de revestimiento enterico. - Google Patents
Forma de dosificacion que comprende un agente alcalino y una capa de revestimiento enterico.Info
- Publication number
- MX2022007162A MX2022007162A MX2022007162A MX2022007162A MX2022007162A MX 2022007162 A MX2022007162 A MX 2022007162A MX 2022007162 A MX2022007162 A MX 2022007162A MX 2022007162 A MX2022007162 A MX 2022007162A MX 2022007162 A MX2022007162 A MX 2022007162A
- Authority
- MX
- Mexico
- Prior art keywords
- coating layer
- alkaline agent
- dosage form
- enteric coating
- icl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/501—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2813—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La invención se refiere a una forma de dosificación, que comprende: a) un núcleo, que comprende un ingrediente biológicamente activo, que es estable en un grado de al menos el 95% en pH 3 durante 2 horas a 22°C, b) una capa de revestimiento intermedio (ICL) sobre o por encima del núcleo, que comprende un agente alcalino, y c) una capa de revestimiento entérico (ECL) sobre o por encima de la capa de revestimiento intermedio que comprende un polímero entérico, en donde la relación en porcentaje del agente alcalino en la ICL con respecto al polímero entérico en la ECL es del 5 al 95% cuando se calcula por medio de la fórmula: (ver Fórmula).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN201941051238 | 2019-12-11 | ||
PCT/EP2020/075960 WO2021115648A1 (en) | 2019-12-11 | 2020-09-17 | Dosage form comprising an alkaline agent and an enteric coating layer |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022007162A true MX2022007162A (es) | 2022-07-12 |
Family
ID=72659788
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022007162A MX2022007162A (es) | 2019-12-11 | 2020-09-17 | Forma de dosificacion que comprende un agente alcalino y una capa de revestimiento enterico. |
Country Status (10)
Country | Link |
---|---|
US (1) | US20230000780A1 (es) |
EP (1) | EP4072533A1 (es) |
JP (1) | JP2023505714A (es) |
KR (1) | KR20220113697A (es) |
CN (1) | CN114828833A (es) |
BR (1) | BR112022011130A2 (es) |
CA (1) | CA3160876A1 (es) |
IL (1) | IL293651A (es) |
MX (1) | MX2022007162A (es) |
WO (1) | WO2021115648A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112022011055A2 (pt) | 2019-12-11 | 2022-08-23 | Evonik Operations Gmbh | Forma de dosagem para uso no tratamento ou na prevenção de uma doença |
WO2023137556A1 (en) * | 2022-01-20 | 2023-07-27 | Bionxt Solutions Inc. | Chemical composition for enteric drug delivery |
WO2023174722A1 (en) | 2022-03-15 | 2023-09-21 | Evonik Operations Gmbh | Pre-functionalized hard shell capsule with accelerated drug release at ph value 5 to 5.5 |
WO2023214016A1 (en) * | 2022-05-06 | 2023-11-09 | Evonik Operations Gmbh | Dosage form with drug release at ph 3 to 6 using double coating system with at least one release acceleration agent |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2189698A (en) * | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated omeprazole tablets |
US20050214371A1 (en) | 2004-03-03 | 2005-09-29 | Simona Di Capua | Stable pharmaceutical composition comprising an acid labile drug |
DE102005032806A1 (de) | 2005-07-12 | 2007-01-18 | Röhm Gmbh | Verwendung eines teilneutralisierten, anionischen (Meth)acrylat-Copolymers als Überzug für die Herstellung einer Arzneiform mit einer Wirkstofffreisetzung bei erniedrigten pH-Werten |
SI2152250T1 (sl) | 2007-05-07 | 2020-06-30 | Evonik Operations Gmbh | Trdne dozirne oblike, ki vsebujejo enterično oplaščenje s pospešenim sproščanjem zdravila |
CN102626398A (zh) * | 2012-04-18 | 2012-08-08 | 上海腾瑞制药有限公司 | 一种泮托拉唑钠肠溶片及其制备方法 |
MX2015000395A (es) * | 2012-07-12 | 2015-04-10 | Novus Int Inc | Composiciones de matriz y capa para proteccion de bioactivos. |
CA2910865C (en) * | 2014-07-15 | 2016-11-29 | Isa Odidi | Compositions and methods for reducing overdose |
CN105640915A (zh) * | 2016-03-02 | 2016-06-08 | 吉林修正药业新药开发有限公司 | 一种雷贝拉唑钠肠溶片及其制备工艺 |
-
2020
- 2020-09-17 MX MX2022007162A patent/MX2022007162A/es unknown
- 2020-09-17 IL IL293651A patent/IL293651A/en unknown
- 2020-09-17 US US17/757,060 patent/US20230000780A1/en active Pending
- 2020-09-17 CN CN202080085430.1A patent/CN114828833A/zh active Pending
- 2020-09-17 WO PCT/EP2020/075960 patent/WO2021115648A1/en unknown
- 2020-09-17 KR KR1020227019164A patent/KR20220113697A/ko unknown
- 2020-09-17 BR BR112022011130A patent/BR112022011130A2/pt unknown
- 2020-09-17 JP JP2022535765A patent/JP2023505714A/ja active Pending
- 2020-09-17 EP EP20780967.4A patent/EP4072533A1/en active Pending
- 2020-09-17 CA CA3160876A patent/CA3160876A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
KR20220113697A (ko) | 2022-08-16 |
IL293651A (en) | 2022-08-01 |
BR112022011130A2 (pt) | 2022-08-23 |
WO2021115648A1 (en) | 2021-06-17 |
EP4072533A1 (en) | 2022-10-19 |
JP2023505714A (ja) | 2023-02-10 |
CA3160876A1 (en) | 2021-06-17 |
CN114828833A (zh) | 2022-07-29 |
US20230000780A1 (en) | 2023-01-05 |
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