MX2022006472A - Formulacion pediatrica de liberacion inmediata del abridor de canales de potasio ezogabina. - Google Patents
Formulacion pediatrica de liberacion inmediata del abridor de canales de potasio ezogabina.Info
- Publication number
- MX2022006472A MX2022006472A MX2022006472A MX2022006472A MX2022006472A MX 2022006472 A MX2022006472 A MX 2022006472A MX 2022006472 A MX2022006472 A MX 2022006472A MX 2022006472 A MX2022006472 A MX 2022006472A MX 2022006472 A MX2022006472 A MX 2022006472A
- Authority
- MX
- Mexico
- Prior art keywords
- ezogabine
- immediate
- pediatric
- release formulation
- potassium channel
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Emergency Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se divulga en la presente formulaciones farmacéuticas orales de liberación inmediata que comprende una cantidad terapéuticamente efectiva de ezogabina y uno o más excipientes farmacéuticamente aceptables para uso en el tratamiento de la epilepsia y/o del trastorno de crisis epilépticas en un mamífero, preferentemente un humano, más preferentemente un niño. También se divulgan métodos para usar y hacer las formulaciones farmacéuticas orales de liberación inmediata.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962942579P | 2019-12-02 | 2019-12-02 | |
PCT/US2020/062918 WO2021113381A1 (en) | 2019-12-02 | 2020-12-02 | Pediatric immediate-release formulation of the potassium channel opener ezogabine |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022006472A true MX2022006472A (es) | 2022-09-09 |
Family
ID=74181279
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022006472A MX2022006472A (es) | 2019-12-02 | 2020-12-02 | Formulacion pediatrica de liberacion inmediata del abridor de canales de potasio ezogabina. |
Country Status (15)
Country | Link |
---|---|
US (1) | US20210169839A1 (es) |
EP (1) | EP4069201A1 (es) |
JP (1) | JP2023504154A (es) |
KR (1) | KR20220108116A (es) |
CN (1) | CN114760990A (es) |
AU (1) | AU2020395158A1 (es) |
BR (1) | BR112022010458A2 (es) |
CA (1) | CA3162907A1 (es) |
CL (1) | CL2022001426A1 (es) |
CO (1) | CO2022007345A2 (es) |
CR (1) | CR20220313A (es) |
IL (1) | IL293352A (es) |
MX (1) | MX2022006472A (es) |
PE (1) | PE20221396A1 (es) |
WO (1) | WO2021113381A1 (es) |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4200259A1 (de) | 1992-01-08 | 1993-07-15 | Asta Medica Ag | Neue 1,2,4-triaminobenzol-derivate und verfahren zu deren herstellung |
US20100120906A1 (en) * | 2008-07-18 | 2010-05-13 | Valeant Pharmaceuticals International | Modified release formulation and methods of use |
DE102009013613A1 (de) * | 2009-03-17 | 2010-09-23 | Ratiopharm Gmbh | Trockenverarbeitung von Retigabin |
DE102009013612A1 (de) * | 2009-03-17 | 2010-09-23 | Ratiopharm Gmbh | Retigabin-Tabletten, bevorzugt mit modifizierter Freisetzung |
WO2011039369A2 (en) * | 2009-10-02 | 2011-04-07 | Medichem S.A. | Amorphous forms of a 2-amino-4-(4-fluorobenzylamino)phenylcarbamate derivative |
SG181827A1 (en) * | 2010-01-20 | 2012-07-30 | Glaxo Group Ltd | Novel retigabine composition |
US20130267590A1 (en) * | 2011-09-13 | 2013-10-10 | Dr. Reddy's Laboratories Limited | Retigabine compositions |
-
2020
- 2020-12-02 KR KR1020227022012A patent/KR20220108116A/ko unknown
- 2020-12-02 BR BR112022010458A patent/BR112022010458A2/pt not_active Application Discontinuation
- 2020-12-02 IL IL293352A patent/IL293352A/en unknown
- 2020-12-02 MX MX2022006472A patent/MX2022006472A/es unknown
- 2020-12-02 WO PCT/US2020/062918 patent/WO2021113381A1/en active Application Filing
- 2020-12-02 CN CN202080083899.1A patent/CN114760990A/zh active Pending
- 2020-12-02 CA CA3162907A patent/CA3162907A1/en active Pending
- 2020-12-02 PE PE2022000976A patent/PE20221396A1/es unknown
- 2020-12-02 JP JP2022532603A patent/JP2023504154A/ja active Pending
- 2020-12-02 CR CR20220313A patent/CR20220313A/es unknown
- 2020-12-02 AU AU2020395158A patent/AU2020395158A1/en active Pending
- 2020-12-02 US US17/109,937 patent/US20210169839A1/en not_active Abandoned
- 2020-12-02 EP EP20839421.3A patent/EP4069201A1/en active Pending
-
2022
- 2022-05-27 CO CONC2022/0007345A patent/CO2022007345A2/es unknown
- 2022-05-31 CL CL2022001426A patent/CL2022001426A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
PE20221396A1 (es) | 2022-09-14 |
KR20220108116A (ko) | 2022-08-02 |
CL2022001426A1 (es) | 2023-03-24 |
IL293352A (en) | 2022-07-01 |
JP2023504154A (ja) | 2023-02-01 |
WO2021113381A1 (en) | 2021-06-10 |
CR20220313A (es) | 2022-10-31 |
CO2022007345A2 (es) | 2022-06-10 |
CN114760990A (zh) | 2022-07-15 |
US20210169839A1 (en) | 2021-06-10 |
BR112022010458A2 (pt) | 2022-09-06 |
EP4069201A1 (en) | 2022-10-12 |
AU2020395158A1 (en) | 2022-06-23 |
CA3162907A1 (en) | 2021-06-10 |
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