MX2022002961A - Metodos para tratar enfermedades neovasculares oculares usando variantes de aav2 que codifican para aflibercept. - Google Patents

Metodos para tratar enfermedades neovasculares oculares usando variantes de aav2 que codifican para aflibercept.

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Publication number
MX2022002961A
MX2022002961A MX2022002961A MX2022002961A MX2022002961A MX 2022002961 A MX2022002961 A MX 2022002961A MX 2022002961 A MX2022002961 A MX 2022002961A MX 2022002961 A MX2022002961 A MX 2022002961A MX 2022002961 A MX2022002961 A MX 2022002961A
Authority
MX
Mexico
Prior art keywords
aav2
amino acid
methods
ocular neovascular
aflibercept
Prior art date
Application number
MX2022002961A
Other languages
English (en)
Spanish (es)
Inventor
Mehdi Gasmi
Aaron Osborne
Szilard Kiss
Adam Turpcu
Original Assignee
Adverum Biotechnologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2019/062066 external-priority patent/WO2021050094A1/en
Application filed by Adverum Biotechnologies Inc filed Critical Adverum Biotechnologies Inc
Priority claimed from PCT/US2020/050079 external-priority patent/WO2021050649A1/en
Publication of MX2022002961A publication Critical patent/MX2022002961A/es

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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • A61K9/0048—Eye, e.g. artificial tears
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C12N2750/14011—Parvoviridae
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    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Wood Science & Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MX2022002961A 2019-09-11 2020-09-10 Metodos para tratar enfermedades neovasculares oculares usando variantes de aav2 que codifican para aflibercept. MX2022002961A (es)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962899070P 2019-09-11 2019-09-11
US201962913648P 2019-10-10 2019-10-10
PCT/US2019/062066 WO2021050094A1 (en) 2019-09-11 2019-11-18 Methods of treating ocular neovascular diseases using aav2 variants encoding aflibercept
US202062959784P 2020-01-10 2020-01-10
US202062971835P 2020-02-07 2020-02-07
US202063019190P 2020-05-01 2020-05-01
US202063030819P 2020-05-27 2020-05-27
US202063063203P 2020-08-07 2020-08-07
PCT/US2020/050079 WO2021050649A1 (en) 2019-09-11 2020-09-10 Methods of treating ocular neovascular diseases using aav2 variants encoding aflibercept

Publications (1)

Publication Number Publication Date
MX2022002961A true MX2022002961A (es) 2022-04-06

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MX2022002961A MX2022002961A (es) 2019-09-11 2020-09-10 Metodos para tratar enfermedades neovasculares oculares usando variantes de aav2 que codifican para aflibercept.

Country Status (16)

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US (1) US20210100856A1 (enExample)
EP (2) EP4696318A1 (enExample)
JP (2) JP2022547541A (enExample)
DK (1) DK4027983T3 (enExample)
ES (1) ES3063491T3 (enExample)
FI (1) FI4027983T3 (enExample)
HR (1) HRP20260137T1 (enExample)
LT (1) LT4027983T (enExample)
MX (1) MX2022002961A (enExample)
PL (1) PL4027983T3 (enExample)
PT (1) PT4027983T (enExample)
RS (1) RS67774B1 (enExample)
SI (1) SI4027983T1 (enExample)
SM (1) SMT202600070T1 (enExample)
TW (1) TW202117016A (enExample)
UY (1) UY38881A (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS67656B1 (sr) 2018-05-10 2026-02-27 Regeneron Pharma Formulacije koje sadrže visoke koncentracije fuzionog proteina vegf receptora
PE20240329A1 (es) 2019-06-05 2024-02-27 Regeneron Pharma Dispositivos y metodos para administracion de dosis de precision
US12649031B2 (en) 2021-09-08 2026-06-09 Regeneron Pharmaceuticals, Inc. Methods for delivering agents with pre-filled syringes to minimize intraocular inflammation
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device
WO2025010334A2 (en) * 2023-07-05 2025-01-09 Adverum Biotechnologies, Inc. Methods of treating ocular neovascular diseases using aav2 variants encoding aflibercept
AR130449A1 (es) 2023-09-11 2024-12-11 Cuarsagro Sa Conjunto de montaje y extracción de olores para inodoros
WO2026019797A1 (en) * 2024-07-16 2026-01-22 4D Molecular Therapeutics, Inc. Methods for treating wet age-related macular degeneration with adeno-associated virus

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2544136B2 (ja) * 1986-05-23 1996-10-16 第一製薬株式会社 硫酸化多糖体ds4152を含有する血管新生抑制剤及び抗腫瘍剤
TW201105363A (en) * 2009-07-14 2011-02-16 Univ Yamagata Eye drop for macular edema treatment
DK3693025T3 (da) 2011-04-22 2022-01-10 Univ California Adenoassocierede virus-virioner med variant capsid og fremgangsmåder til anvendelse heraf
US20160051526A1 (en) * 2013-04-09 2016-02-25 Cresset Biomolecular Discovery Ltd The Local Treatment of Inflammatory Ophthalmic Disorders
CN117531025A (zh) * 2016-06-16 2024-02-09 阿德夫拉姆生物技术股份有限公司 使用aav2变体和阿柏西普治疗amd
KR102616820B1 (ko) * 2017-03-17 2023-12-21 애드베룸 바이오테크놀로지스, 인코포레이티드 향상된 유전자 발현을 위한 조성물 및 방법
KR20210068014A (ko) * 2018-08-20 2021-06-08 우한 뉴로프스 바이오테크놀로지 리미티드 컴퍼니 레버 유전성 시신경병증의 치료를 위한 조성물 및 방법

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Publication number Publication date
EP4027983A1 (en) 2022-07-20
RS67774B1 (sr) 2026-03-31
TW202117016A (zh) 2021-05-01
SMT202600070T1 (it) 2026-03-09
UY38881A (es) 2021-04-30
PL4027983T3 (pl) 2026-05-11
FI4027983T3 (fi) 2026-02-03
LT4027983T (lt) 2026-02-25
US20210100856A1 (en) 2021-04-08
JP2025118798A (ja) 2025-08-13
JP2022547541A (ja) 2022-11-14
PT4027983T (pt) 2026-02-25
EP4027983B1 (en) 2025-11-19
EP4696318A1 (en) 2026-02-18
SI4027983T1 (sl) 2026-06-30
DK4027983T3 (da) 2026-02-09
ES3063491T3 (en) 2026-04-16
HRP20260137T1 (hr) 2026-03-13

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