MX2022002568A - Proceso para preparar (r)-4-aminoindano y amidas correspondientes. - Google Patents

Proceso para preparar (r)-4-aminoindano y amidas correspondientes.

Info

Publication number
MX2022002568A
MX2022002568A MX2022002568A MX2022002568A MX2022002568A MX 2022002568 A MX2022002568 A MX 2022002568A MX 2022002568 A MX2022002568 A MX 2022002568A MX 2022002568 A MX2022002568 A MX 2022002568A MX 2022002568 A MX2022002568 A MX 2022002568A
Authority
MX
Mexico
Prior art keywords
preparing
formula
aminoindane
corresponding amides
relates
Prior art date
Application number
MX2022002568A
Other languages
English (en)
Inventor
Paolo Bellandi
Giampaolo Zanardi
Pierangelo Mereghetti
Original Assignee
Fmc Agricultural Products Int Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Agricultural Products Int Ag filed Critical Fmc Agricultural Products Int Ag
Publication of MX2022002568A publication Critical patent/MX2022002568A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/62—Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/57—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems of the carbon skeleton
    • C07C211/59—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems of the carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/57—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems of the carbon skeleton
    • C07C211/60—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems of the carbon skeleton containing a ring other than a six-membered aromatic ring forming part of at least one of the condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a un proceso para preparar 1,1,3-trimetilindan-4-amina de la fórmula (I), o una sal de los mismos, enriquecida en uno de sus dos enantiómeros, en particular el enantiómero (R), (ver Fórmula) (I) que comprende la separación quiral de una 2,2,4-trimetil-1,2,3,4-tetrahidroquinolina opcionalmente sustituida de la fórmula (III) (ver Fórmula) (III) La presente invención también se refiere a un proceso para preparar amidas ópticamente activas de la fórmula (II) (ver Fórmula) (II) a partir de tales compuestos de la fórmula (I).
MX2022002568A 2019-09-26 2020-09-23 Proceso para preparar (r)-4-aminoindano y amidas correspondientes. MX2022002568A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT102019000017330A IT201900017330A1 (it) 2019-09-26 2019-09-26 Processo per la preparazione di (r)-4-amminoindani e corrispondenti ammidi.
PCT/IB2020/058865 WO2021059146A1 (en) 2019-09-26 2020-09-23 Process for preparing (r)-4-aminoindane and corresponding amides

Publications (1)

Publication Number Publication Date
MX2022002568A true MX2022002568A (es) 2022-06-02

Family

ID=69375849

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022002568A MX2022002568A (es) 2019-09-26 2020-09-23 Proceso para preparar (r)-4-aminoindano y amidas correspondientes.

Country Status (12)

Country Link
US (1) US20220315521A1 (es)
EP (1) EP4038047A1 (es)
JP (1) JP2022550006A (es)
KR (1) KR20220071183A (es)
CN (1) CN114728884A (es)
AR (1) AR120042A1 (es)
AU (1) AU2020355394A1 (es)
BR (1) BR112022004078A2 (es)
IL (1) IL291002A (es)
IT (1) IT201900017330A1 (es)
MX (1) MX2022002568A (es)
WO (1) WO2021059146A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114773263B (zh) * 2022-05-16 2023-09-05 江苏百康德医药科技有限公司 (r)-2,2,4-三甲基-1,2,3,4-四氢喹啉的制备方法

Family Cites Families (28)

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DK383086A (da) 1985-08-21 1987-02-22 Rohm & Haas (2-cyano-2-arylethyl)pyridiner, deres fremstilling og deres anvendelse som fungicider
DE3782883T2 (de) 1986-08-12 1993-06-09 Mitsubishi Chem Ind Pyridincarboxamid-derivate und ihre verwendung als fungizides mittel.
US4837242A (en) 1987-01-20 1989-06-06 Sumitomo Chemical Company, Limited Thiazoles and pyrazoles as fungicides
US4914097A (en) 1987-02-25 1990-04-03 Mitsubishi Kasei Corporation N-indanyl carboxamide derivative and agricultural/horticultural fungicide containing the derivative as active ingredient
JP2582863B2 (ja) 1988-06-13 1997-02-19 三菱化学株式会社 Ｎ−インダニルカルボン酸アミド誘導体を有効成分とする灰色かび病防除剤
JP2717852B2 (ja) 1988-12-09 1998-02-25 株式会社紀文食品 冷凍すり身の鮮度測定法
JPH02157266A (ja) 1988-12-12 1990-06-18 Mitsubishi Kasei Corp Ｎ−インダニルカルボン酸アミド誘導体およびこれを有効成分とする農園芸用殺菌剤
US5093347A (en) 1991-01-28 1992-03-03 Monsanto Company 3-difluoromethylpyrazolecarboxamide fungicides, compositions and use
JP3077381B2 (ja) 1992-05-14 2000-08-14 住友化学工業株式会社 木材防腐剤
US5521317A (en) 1993-10-22 1996-05-28 American Cyanamid Co. Processes for the preparation of pesticides and intermediates
EP0654464A1 (en) * 1993-10-22 1995-05-24 Shell Internationale Researchmaatschappij B.V. Processes for the preparation of pesticides and intermediates
JPH1070479A (ja) 1996-08-29 1998-03-10 Nippon Seiki Co Ltd Ｆｍ多重受信機
JP3675112B2 (ja) 1997-06-23 2005-07-27 富士写真フイルム株式会社 画像読取装置及び情報処理装置
GB0001447D0 (en) 2000-01-21 2000-03-08 Novartis Ag Organic compounds
ATE516275T1 (de) 2002-08-22 2011-07-15 Syngenta Participations Ag Microbiozide (z.b. fungizide) 1,2,3- triazolderivate
DE10250110A1 (de) 2002-10-28 2004-05-13 Bayer Cropscience Ag Thiazol-(bi)cycloalkyl-carboxanilide
CA2515922A1 (en) 2003-02-14 2004-08-26 Ralf Dunkel Oxathiin carboxamide
WO2004103975A1 (de) 2003-05-21 2004-12-02 Bayer Cropscience Aktiengesellschaft Iodpyrazolylcarboxanilide
DE102004005785A1 (de) 2004-02-06 2005-08-25 Bayer Cropscience Ag 2-Halogenfuryl/thienyl-3-carboxamide
JP2012025735A (ja) 2010-06-24 2012-02-09 Sumitomo Chemical Co Ltd 植物病害防除組成物及び植物病害防除方法
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ITMI20121045A1 (it) * 2012-06-15 2013-12-16 Isagro Ricerca Srl Composizioni sinergiche per la protezione di colture agrarie e relativo uso
CN105555769A (zh) * 2013-07-19 2016-05-04 斯洛文尼亚莱柯制药股份有限公司 不需要的对映异构体的外消旋化方法
EP3103789B1 (en) * 2014-02-07 2018-10-31 Sumitomo Chemical Company Limited Method for producing (r)-1,1,3-trimethyl-4-aminoindane
DE102015213424A1 (de) 2015-07-16 2017-01-19 Audi Ag Verfahren und Bediensystem zum Bedienen von mindestens einer Funktion in einem Fahrzeug
JP7021100B2 (ja) * 2016-03-17 2022-02-16 エフ エム シー コーポレーション Ｓ－エナンチオマーのラセミ体への変換方法
US10640454B2 (en) 2016-04-15 2020-05-05 Stichting I-F Product Collaboration Processes for preparation of 4-aminoindane compounds and related aminoindane amides

Also Published As

Publication number Publication date
AU2020355394A1 (en) 2022-03-24
IT201900017330A1 (it) 2021-03-26
KR20220071183A (ko) 2022-05-31
BR112022004078A2 (pt) 2022-05-31
US20220315521A1 (en) 2022-10-06
JP2022550006A (ja) 2022-11-30
AR120042A1 (es) 2022-01-26
CN114728884A (zh) 2022-07-08
IL291002A (en) 2022-05-01
WO2021059146A1 (en) 2021-04-01
EP4038047A1 (en) 2022-08-10
TW202126615A (zh) 2021-07-16

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