MX2022002328A - Metodos de un solo paso, kits, y sistemas para la medicion de concentraciones de bilirrubina no enlazada en fluidos biologicos. - Google Patents
Metodos de un solo paso, kits, y sistemas para la medicion de concentraciones de bilirrubina no enlazada en fluidos biologicos.Info
- Publication number
- MX2022002328A MX2022002328A MX2022002328A MX2022002328A MX2022002328A MX 2022002328 A MX2022002328 A MX 2022002328A MX 2022002328 A MX2022002328 A MX 2022002328A MX 2022002328 A MX2022002328 A MX 2022002328A MX 2022002328 A MX2022002328 A MX 2022002328A
- Authority
- MX
- Mexico
- Prior art keywords
- kits
- concentrations
- measurement
- systems
- biological fluids
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Se describen la identificación y el uso de proteínas etiquetadas fluorescentemente y que experimentan un cambio en índice de fluorescencia tras unirse a la bilirrubina. Se divulgan sondas que se etiquetan en un residuo de cisteína o lisina y también se etiquetan sondas en ambas de la cisteína y la lisina con dos fluoróforos diferentes. Estas ondas son útiles para la determinación de niveles de bilirrubina no enlazada en una muestra de fluido.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962894553P | 2019-08-30 | 2019-08-30 | |
PCT/US2020/048264 WO2021041720A1 (en) | 2019-08-30 | 2020-08-27 | One step methods, kits, and systems for the measurement of concentrations of unbound bilirubin in biological fluids |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022002328A true MX2022002328A (es) | 2022-06-02 |
Family
ID=74685308
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022002328A MX2022002328A (es) | 2019-08-30 | 2020-08-27 | Metodos de un solo paso, kits, y sistemas para la medicion de concentraciones de bilirrubina no enlazada en fluidos biologicos. |
Country Status (9)
Country | Link |
---|---|
US (1) | US20230053493A1 (es) |
EP (1) | EP4022317A4 (es) |
JP (1) | JP2022546707A (es) |
KR (1) | KR20220104676A (es) |
CN (1) | CN114467032A (es) |
AU (1) | AU2020340383A1 (es) |
CA (1) | CA3152537A1 (es) |
MX (1) | MX2022002328A (es) |
WO (1) | WO2021041720A1 (es) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012054784A1 (en) * | 2010-10-20 | 2012-04-26 | Li-Cor, Inc. | Fluorescent imaging with substituted cyanine dyes |
MX347754B (es) * | 2011-08-26 | 2017-05-11 | Alan Marc Kleinfeld | Desarrollo y uso de sondas fluorescentes de bilirrubina sin enlazar. |
-
2020
- 2020-08-27 AU AU2020340383A patent/AU2020340383A1/en active Pending
- 2020-08-27 WO PCT/US2020/048264 patent/WO2021041720A1/en unknown
- 2020-08-27 EP EP20856414.6A patent/EP4022317A4/en active Pending
- 2020-08-27 KR KR1020227008739A patent/KR20220104676A/ko unknown
- 2020-08-27 CA CA3152537A patent/CA3152537A1/en active Pending
- 2020-08-27 MX MX2022002328A patent/MX2022002328A/es unknown
- 2020-08-27 CN CN202080061275.XA patent/CN114467032A/zh active Pending
- 2020-08-27 JP JP2022513380A patent/JP2022546707A/ja active Pending
- 2020-08-27 US US17/632,202 patent/US20230053493A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP4022317A4 (en) | 2023-08-16 |
KR20220104676A (ko) | 2022-07-26 |
US20230053493A1 (en) | 2023-02-23 |
WO2021041720A1 (en) | 2021-03-04 |
EP4022317A1 (en) | 2022-07-06 |
AU2020340383A1 (en) | 2022-04-14 |
CN114467032A (zh) | 2022-05-10 |
CA3152537A1 (en) | 2021-03-04 |
JP2022546707A (ja) | 2022-11-07 |
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