MX2021013363A - Metodo para la prediccion de eficacia del tratamiento de hemoglobinopatia. - Google Patents

Metodo para la prediccion de eficacia del tratamiento de hemoglobinopatia.

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Publication number
MX2021013363A
MX2021013363A MX2021013363A MX2021013363A MX2021013363A MX 2021013363 A MX2021013363 A MX 2021013363A MX 2021013363 A MX2021013363 A MX 2021013363A MX 2021013363 A MX2021013363 A MX 2021013363A MX 2021013363 A MX2021013363 A MX 2021013363A
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MX
Mexico
Prior art keywords
modified
individual
hemoglobinopathy
population
treatment
Prior art date
Application number
MX2021013363A
Other languages
English (en)
Spanish (es)
Inventor
Huihui Yang
Riguo Fang
Lingling Yu
Original Assignee
Edigene Guangzhou Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Edigene Guangzhou Inc filed Critical Edigene Guangzhou Inc
Publication of MX2021013363A publication Critical patent/MX2021013363A/es

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    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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MX2021013363A 2019-04-30 2020-04-29 Metodo para la prediccion de eficacia del tratamiento de hemoglobinopatia. MX2021013363A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2019085116 2019-04-30
PCT/CN2020/087766 WO2020221291A1 (zh) 2019-04-30 2020-04-29 一种血红蛋白病治疗有效性预测方法

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MX2021013363A true MX2021013363A (es) 2021-11-18

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MX2021013363A MX2021013363A (es) 2019-04-30 2020-04-29 Metodo para la prediccion de eficacia del tratamiento de hemoglobinopatia.

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EP (1) EP3964579A4 (enExample)
JP (1) JP2022531269A (enExample)
KR (1) KR20220002565A (enExample)
CN (1) CN113785059A (enExample)
AU (1) AU2020265060A1 (enExample)
BR (1) BR112021021744A8 (enExample)
CA (1) CA3138029A1 (enExample)
CL (1) CL2021002854A1 (enExample)
CO (1) CO2021016058A2 (enExample)
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EA (1) EA202192931A1 (enExample)
IL (1) IL287672A (enExample)
MA (1) MA55817A (enExample)
MX (1) MX2021013363A (enExample)
PE (1) PE20220003A1 (enExample)
PH (1) PH12021552732A1 (enExample)
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Publication number Priority date Publication date Assignee Title
CR20210572A (es) 2019-04-15 2022-04-07 Univ Beijing Métodos y composiciones para editar ácido ribonucleicos (arn)
MX2022000497A (es) 2019-07-12 2022-02-03 Univ Beijing Edicion de acido ribonucleico (arn) dirigido aprovechando la adenosina desaminasa que actua sobre acido ribonucleico endogeno (adar) utilizando acidos ribonucleicos (arn) modificados geneticamente.
BR112023019773A2 (pt) * 2021-04-02 2024-03-12 Univ Shanghai Technology Método para promover a produção de gama-globina em uma célula humana, polinucleotídeos codificando uma proteína associada a um crispr (cas), uma nucleobase desaminase, um rna de guia único (sgrna) e um rna de guia único auxiliar (hsgrna), e, proteína de fusão

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SG11201405103SA (en) * 2012-02-24 2014-09-26 Hutchinson Fred Cancer Res Compositions and methods for the treatment of hemoglobinopathies
MY189533A (en) 2012-05-25 2022-02-16 Univ California Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription
KR20230065381A (ko) 2012-07-25 2023-05-11 더 브로드 인스티튜트, 인코퍼레이티드 유도 ｄｎａ 결합 단백질 및 게놈 교란 도구 및 이의 적용
WO2014065596A1 (en) 2012-10-23 2014-05-01 Toolgen Incorporated Composition for cleaving a target dna comprising a guide rna specific for the target dna and cas protein-encoding nucleic acid or cas protein, and use thereof
PT3502240T (pt) * 2012-11-27 2021-08-11 Childrens Medical Ct Corp Elementos reguladores distais de bcl11a como alvo para a reindução de hemoglobina fetal
US8697359B1 (en) 2012-12-12 2014-04-15 The Broad Institute, Inc. CRISPR-Cas systems and methods for altering expression of gene products
WO2016135558A2 (en) * 2015-02-23 2016-09-01 Crispr Therapeutics Ag Materials and methods for treatment of hemoglobinopathies
SG11201805217XA (en) * 2015-12-28 2018-07-30 Novartis Ag Compositions and methods for the treatment of hemoglobinopathies
TW201839136A (zh) * 2017-02-06 2018-11-01 瑞士商諾華公司 治療血色素異常症之組合物及方法
US11788087B2 (en) * 2017-05-25 2023-10-17 The Children's Medical Center Corporation BCL11A guide delivery

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CA3138029A1 (en) 2020-11-05
WO2020221291A1 (zh) 2020-11-05
PH12021552732A1 (en) 2023-01-16
IL287672A (en) 2021-12-01
EA202192931A1 (ru) 2022-02-22
MA55817A (fr) 2022-03-09
JP2022531269A (ja) 2022-07-06
CN113785059A (zh) 2021-12-10
BR112021021744A8 (pt) 2023-03-21
US20220193142A1 (en) 2022-06-23
CR20210591A (es) 2022-03-11
KR20220002565A (ko) 2022-01-06
SG11202112072QA (en) 2021-12-30
PE20220003A1 (es) 2022-01-05
CL2021002854A1 (es) 2022-08-12
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