BR112021021744A8 - Métodos para tratar hemoglobinopatia e para determinar se um indivíduo sofrendo de hemoglobinopatia é adequado ou inadequado para tratar com uma segunda população das hspcs positivas em cd34 modificadas - Google Patents

Métodos para tratar hemoglobinopatia e para determinar se um indivíduo sofrendo de hemoglobinopatia é adequado ou inadequado para tratar com uma segunda população das hspcs positivas em cd34 modificadas

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Publication number
BR112021021744A8
BR112021021744A8 BR112021021744A BR112021021744A BR112021021744A8 BR 112021021744 A8 BR112021021744 A8 BR 112021021744A8 BR 112021021744 A BR112021021744 A BR 112021021744A BR 112021021744 A BR112021021744 A BR 112021021744A BR 112021021744 A8 BR112021021744 A8 BR 112021021744A8
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Brazil
Prior art keywords
modified
hemoglobinopathy
population
positive
inappropriate
Prior art date
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BR112021021744A
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English (en)
Portuguese (pt)
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BR112021021744A2 (enExample
Inventor
Fang Riguo
Yu Lingling
Yang Huihui
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Edigene Inc
Edigene Guangzhou Inc
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Application filed by Edigene Inc, Edigene Guangzhou Inc filed Critical Edigene Inc
Publication of BR112021021744A2 publication Critical patent/BR112021021744A2/pt
Publication of BR112021021744A8 publication Critical patent/BR112021021744A8/pt

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BR112021021744A 2019-04-30 2020-04-29 Métodos para tratar hemoglobinopatia e para determinar se um indivíduo sofrendo de hemoglobinopatia é adequado ou inadequado para tratar com uma segunda população das hspcs positivas em cd34 modificadas BR112021021744A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2019085116 2019-04-30
PCT/CN2020/087766 WO2020221291A1 (zh) 2019-04-30 2020-04-29 一种血红蛋白病治疗有效性预测方法

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BR112021021744A2 BR112021021744A2 (enExample) 2021-12-28
BR112021021744A8 true BR112021021744A8 (pt) 2023-03-21

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MX2022000497A (es) 2019-07-12 2022-02-03 Univ Beijing Edicion de acido ribonucleico (arn) dirigido aprovechando la adenosina desaminasa que actua sobre acido ribonucleico endogeno (adar) utilizando acidos ribonucleicos (arn) modificados geneticamente.
BR112023019773A2 (pt) * 2021-04-02 2024-03-12 Univ Shanghai Technology Método para promover a produção de gama-globina em uma célula humana, polinucleotídeos codificando uma proteína associada a um crispr (cas), uma nucleobase desaminase, um rna de guia único (sgrna) e um rna de guia único auxiliar (hsgrna), e, proteína de fusão

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PT3502240T (pt) * 2012-11-27 2021-08-11 Childrens Medical Ct Corp Elementos reguladores distais de bcl11a como alvo para a reindução de hemoglobina fetal
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WO2016135558A2 (en) * 2015-02-23 2016-09-01 Crispr Therapeutics Ag Materials and methods for treatment of hemoglobinopathies
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TW201839136A (zh) * 2017-02-06 2018-11-01 瑞士商諾華公司 治療血色素異常症之組合物及方法
US11788087B2 (en) * 2017-05-25 2023-10-17 The Children's Medical Center Corporation BCL11A guide delivery

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