EA202192931A1 - Способ прогнозирования эффективности лечения гемоглобинопатии - Google Patents

Способ прогнозирования эффективности лечения гемоглобинопатии

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Publication number
EA202192931A1
EA202192931A1 EA202192931A EA202192931A EA202192931A1 EA 202192931 A1 EA202192931 A1 EA 202192931A1 EA 202192931 A EA202192931 A EA 202192931A EA 202192931 A EA202192931 A EA 202192931A EA 202192931 A1 EA202192931 A1 EA 202192931A1
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EA
Eurasian Patent Office
Prior art keywords
modified
individual
treatment
population
hemoglobinopathy
Prior art date
Application number
EA202192931A
Other languages
English (en)
Russian (ru)
Inventor
Жиго Фан
Линлин Юй
Хуэйхуэй ЯН
Original Assignee
Эдиджен Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эдиджен Инк. filed Critical Эдиджен Инк.
Publication of EA202192931A1 publication Critical patent/EA202192931A1/ru

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EA202192931A 2019-04-30 2020-04-29 Способ прогнозирования эффективности лечения гемоглобинопатии EA202192931A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2019085116 2019-04-30
PCT/CN2020/087766 WO2020221291A1 (zh) 2019-04-30 2020-04-29 一种血红蛋白病治疗有效性预测方法

Publications (1)

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EA202192931A1 true EA202192931A1 (ru) 2022-02-22

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US (1) US20220193142A1 (enExample)
EP (1) EP3964579A4 (enExample)
JP (1) JP2022531269A (enExample)
KR (1) KR20220002565A (enExample)
CN (1) CN113785059A (enExample)
AU (1) AU2020265060A1 (enExample)
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CR (1) CR20210591A (enExample)
EA (1) EA202192931A1 (enExample)
IL (1) IL287672A (enExample)
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MX (1) MX2021013363A (enExample)
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CA3136735A1 (en) 2019-04-15 2020-10-22 Edigene Inc. Methods and compositions for editing rnas
AU2020313143B2 (en) 2019-07-12 2024-04-04 Peking University Targeted RNA editing by leveraging endogenous adar using engineered RNAs
EP4314308A4 (en) * 2021-04-02 2026-05-20 Univ Shanghai Technology GENE THERAPY FOR THE TREATMENT OF BETA-HEMOGLOBINOPATHIES

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EP2836226B1 (en) * 2012-02-24 2017-06-28 Fred Hutchinson Cancer Research Center Compositions and methods for the treatment of hemoglobinopathies
ES2728782T3 (es) 2012-05-25 2019-10-28 Univ California Métodos y composiciones para la modificación de ADN objetivo dirigida por ARN y para la modulación de la transcripción dirigida por ARN
CN116622704A (zh) 2012-07-25 2023-08-22 布罗德研究所有限公司 可诱导的dna结合蛋白和基因组干扰工具及其应用
EP4397759A3 (en) 2012-10-23 2024-10-09 Toolgen Incorporated Composition for cleaving a target dna comprising a guide rna specific for the target dna and cas protein-encoding nucleic acid or cas protein, and use thereof
ES2708948T3 (es) * 2012-11-27 2019-04-12 Childrens Medical Ct Corp Elementos reguladores distales de bcl11a como dianas para la reinducción de la hemoglobina fetal
US8697359B1 (en) 2012-12-12 2014-04-15 The Broad Institute, Inc. CRISPR-Cas systems and methods for altering expression of gene products
WO2016135558A2 (en) * 2015-02-23 2016-09-01 Crispr Therapeutics Ag Materials and methods for treatment of hemoglobinopathies
MX2018007987A (es) * 2015-12-28 2019-01-10 Novartis Ag Composiciones y metodos para el tratamiento de hemoglobinopatias.
TW201839136A (zh) * 2017-02-06 2018-11-01 瑞士商諾華公司 治療血色素異常症之組合物及方法
US11788087B2 (en) * 2017-05-25 2023-10-17 The Children's Medical Center Corporation BCL11A guide delivery

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EP3964579A4 (en) 2023-07-26
US20220193142A1 (en) 2022-06-23
SG11202112072QA (en) 2021-12-30
EP3964579A1 (en) 2022-03-09
BR112021021744A8 (pt) 2023-03-21
IL287672A (en) 2021-12-01
MX2021013363A (es) 2021-11-18
WO2020221291A1 (zh) 2020-11-05
CL2021002854A1 (es) 2022-08-12
CO2021016058A2 (es) 2021-12-10
CA3138029A1 (en) 2020-11-05
BR112021021744A2 (enExample) 2021-12-28
PH12021552732A1 (en) 2023-01-16
JP2022531269A (ja) 2022-07-06
MA55817A (fr) 2022-03-09
CN113785059A (zh) 2021-12-10
PE20220003A1 (es) 2022-01-05
KR20220002565A (ko) 2022-01-06
CR20210591A (es) 2022-03-11
AU2020265060A1 (en) 2021-12-16

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