MX2021011047A - Preparaciones de agentes terapéuticos y métodos para la administración de fármacos en un lumen del tracto intestinal usando un dispositivo de administración de fármacos ingerible. - Google Patents
Preparaciones de agentes terapéuticos y métodos para la administración de fármacos en un lumen del tracto intestinal usando un dispositivo de administración de fármacos ingerible.Info
- Publication number
- MX2021011047A MX2021011047A MX2021011047A MX2021011047A MX2021011047A MX 2021011047 A MX2021011047 A MX 2021011047A MX 2021011047 A MX2021011047 A MX 2021011047A MX 2021011047 A MX2021011047 A MX 2021011047A MX 2021011047 A MX2021011047 A MX 2021011047A
- Authority
- MX
- Mexico
- Prior art keywords
- drug delivery
- capsule
- methods
- swallowable
- lumen
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 6
- 238000002360 preparation method Methods 0.000 title abstract 6
- 229940124597 therapeutic agent Drugs 0.000 title abstract 5
- 210000001035 gastrointestinal tract Anatomy 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000012377 drug delivery Methods 0.000 title 2
- 239000002775 capsule Substances 0.000 abstract 5
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
- 230000000968 intestinal effect Effects 0.000 abstract 1
- 230000036470 plasma concentration Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962818053P | 2019-03-13 | 2019-03-13 | |
| US201962820174P | 2019-03-18 | 2019-03-18 | |
| PCT/US2020/022496 WO2020186121A1 (en) | 2019-03-13 | 2020-03-12 | Therapeutic agent preparations and methods for drug delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2021011047A true MX2021011047A (es) | 2021-12-15 |
Family
ID=72424820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021011047A MX2021011047A (es) | 2019-03-13 | 2020-03-12 | Preparaciones de agentes terapéuticos y métodos para la administración de fármacos en un lumen del tracto intestinal usando un dispositivo de administración de fármacos ingerible. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20200289620A1 (enExample) |
| EP (1) | EP3937971A4 (enExample) |
| JP (1) | JP2022524446A (enExample) |
| KR (1) | KR20210138646A (enExample) |
| CN (1) | CN113784724A (enExample) |
| AU (1) | AU2020237517A1 (enExample) |
| BR (1) | BR112021017993A2 (enExample) |
| CA (1) | CA3133086A1 (enExample) |
| MX (1) | MX2021011047A (enExample) |
| WO (1) | WO2020186121A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8721620B2 (en) | 2009-12-24 | 2014-05-13 | Rani Therapeutics, Llc | Swallowable drug delivery device and methods of drug delivery |
| US8809269B2 (en) | 2010-12-23 | 2014-08-19 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8734429B2 (en) | 2010-12-23 | 2014-05-27 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
| US9415004B2 (en) | 2010-12-23 | 2016-08-16 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9402806B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9259386B2 (en) | 2010-12-23 | 2016-02-16 | Rani Therapeutics, Llc | Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10689460B2 (en) | 2014-05-15 | 2020-06-23 | Incube Labs, Llc | PCSK9 antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| AU2018366110B2 (en) * | 2017-11-07 | 2024-08-08 | Rani Therapeutics, Llc | Clotting factor preparations for delivery into tissue of the intestinal tract using a swallowable drug delivery device |
| CN112451500B (zh) * | 2020-12-18 | 2022-05-17 | 南京鼓楼医院 | 一种磁响应载药微针机器人及其制备方法和应用 |
| WO2025081168A1 (en) * | 2023-10-12 | 2025-04-17 | The Brigham And Women's Hospital, Inc. | An intra-abdominal injection system |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8721620B2 (en) * | 2009-12-24 | 2014-05-13 | Rani Therapeutics, Llc | Swallowable drug delivery device and methods of drug delivery |
| US9284367B2 (en) * | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10639272B2 (en) * | 2010-12-23 | 2020-05-05 | Rani Therapeutics, Llc | Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8980822B2 (en) * | 2010-12-23 | 2015-03-17 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising pramlintide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9629799B2 (en) * | 2010-12-23 | 2017-04-25 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8969293B2 (en) * | 2010-12-23 | 2015-03-03 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising exenatide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9861683B2 (en) * | 2010-12-23 | 2018-01-09 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8734429B2 (en) * | 2010-12-23 | 2014-05-27 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
| US9402806B2 (en) * | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9259386B2 (en) * | 2010-12-23 | 2016-02-16 | Rani Therapeutics, Llc | Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8809269B2 (en) * | 2010-12-23 | 2014-08-19 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9415004B2 (en) * | 2010-12-23 | 2016-08-16 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9283179B2 (en) * | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | GnRH preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9149617B2 (en) * | 2010-12-23 | 2015-10-06 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
| US9402807B2 (en) * | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US11548940B2 (en) * | 2014-05-15 | 2023-01-10 | Rani Therapeutics, Llc | Anti-interleukin antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US20230374155A1 (en) * | 2014-05-15 | 2023-11-23 | Rani Therapeutics, Llc | Pcsk9 antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10689460B2 (en) * | 2014-05-15 | 2020-06-23 | Incube Labs, Llc | PCSK9 antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| WO2015176031A2 (en) * | 2014-05-15 | 2015-11-19 | Incube Labs, Llc | Pharmaceutical compositions and methods for fabrication of solid masses comprising polypeptides and/or proteins |
| CN107847446A (zh) * | 2015-05-01 | 2018-03-27 | 因库博实验室有限责任公司 | 药物组合物和用于制备包含多肽和/或蛋白质的固体块的方法 |
| EP3316872A4 (en) * | 2015-07-02 | 2018-12-26 | Rani Therapeutics, LLC | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| AU2018366110B2 (en) * | 2017-11-07 | 2024-08-08 | Rani Therapeutics, Llc | Clotting factor preparations for delivery into tissue of the intestinal tract using a swallowable drug delivery device |
| US11473339B2 (en) * | 2018-01-31 | 2022-10-18 | Spectrum Brands, Inc. | Field-handable gate latch |
| JP2022516513A (ja) * | 2018-12-31 | 2022-02-28 | ラニ セラピューティクス， エルエルシー | 嚥下可能薬物送達デバイスを使用する腸管の管腔への送達のための治療剤調製物 |
| WO2020227162A1 (en) * | 2019-05-03 | 2020-11-12 | Rani Therapeutics, Llc | Clotting factor preparations for delivery into tissue of the intestinal tract using a swallowable drug delivery device |
-
2020
- 2020-03-12 EP EP20770263.0A patent/EP3937971A4/en not_active Withdrawn
- 2020-03-12 CN CN202080028733.XA patent/CN113784724A/zh active Pending
- 2020-03-12 KR KR1020217032196A patent/KR20210138646A/ko not_active Abandoned
- 2020-03-12 BR BR112021017993A patent/BR112021017993A2/pt unknown
- 2020-03-12 US US16/817,490 patent/US20200289620A1/en not_active Abandoned
- 2020-03-12 WO PCT/US2020/022496 patent/WO2020186121A1/en not_active Ceased
- 2020-03-12 AU AU2020237517A patent/AU2020237517A1/en not_active Abandoned
- 2020-03-12 CA CA3133086A patent/CA3133086A1/en active Pending
- 2020-03-12 MX MX2021011047A patent/MX2021011047A/es unknown
- 2020-03-12 JP JP2021554738A patent/JP2022524446A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2020237517A1 (en) | 2021-10-14 |
| BR112021017993A2 (pt) | 2022-01-18 |
| AU2020237517A2 (en) | 2021-11-04 |
| KR20210138646A (ko) | 2021-11-19 |
| EP3937971A4 (en) | 2022-12-14 |
| CN113784724A (zh) | 2021-12-10 |
| JP2022524446A (ja) | 2022-05-02 |
| US20200289620A1 (en) | 2020-09-17 |
| WO2020186121A1 (en) | 2020-09-17 |
| EP3937971A1 (en) | 2022-01-19 |
| CA3133086A1 (en) | 2020-09-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2021011047A (es) | Preparaciones de agentes terapéuticos y métodos para la administración de fármacos en un lumen del tracto intestinal usando un dispositivo de administración de fármacos ingerible. | |
| MX2024005949A (es) | Preparaciones de agente terapeutico para administracion en un lumen del tracto intestinal utilizando un dispositivo de administracion de farmaco tragable. | |
| WO2011112229A3 (en) | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device | |
| MX2021013310A (es) | Preparaciones de factor de cogulación para la administración en el tejido del tracto intestinal usando un dispositivo de administración de medicamentos ingeribles. | |
| Fasiolo et al. | Opportunity and challenges of nasal powders: Drug formulation and delivery | |
| IN2014CN00338A (enExample) | ||
| MX2021010442A (es) | Dministración de fármacos propulsiva desde un dispositivo ingerible al tracto intestinal de un paciente. | |
| EP3316872A4 (en) | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device | |
| WO2009057774A1 (ja) | 薬液投与システムおよび薬液投与用カニューラ | |
| MX2022009523A (es) | Formulaciones farmaceuticas. | |
| WO2016172396A3 (en) | Multi-chamber sequential delivery syringe | |
| NZ700182A (en) | Parenteral formulations for administering macrolide antibiotics | |
| WO2007109684A3 (en) | Dose packaging system for load-dose titration administration of a liquid formulation | |
| JP2005527535A5 (enExample) | ||
| MY157187A (en) | Drug delivery system for administration of a water soluble, cationic and amphiphilic pharmaceutically active substance | |
| WO2015020943A3 (en) | Digestive enzyme composition suitable for enteral administration | |
| WO2010034016A3 (en) | Diaphragm drug pump | |
| WO2016100949A3 (en) | Method and compositions for dissolving or solubilizing therapeutic agents | |
| MX2013012206A (es) | Metodo para producir substancias con gas sobresaturado,dispositivo de suministro transdermico de las mismas, y usos de las mismas. | |
| EP4473987A4 (en) | Device for administering a medicinal solution | |
| TNSN08144A1 (en) | Kit for parenteral administration of medicaments | |
| BR112017022984A2 (pt) | dispositivo para facilitar o posicionamento de um cateter para administrar um medicamento em um paciente que esteja respirando espontaneamente | |
| WO2012145554A3 (en) | Method of producing substances with supersaturated gas,transdermal delivery device thereof, and uses thereof | |
| WO2012145555A3 (en) | Method of producing substances with supersaturated gas, transdermal delivery device thereof, and uses thereof | |
| WO2004096172A3 (fr) | Vecteur pour administration par voie orale |