MX2021009161A - Acidos nucleicos recombinantes que contienen secuencias promotoras de alfaherpesvirus. - Google Patents
Acidos nucleicos recombinantes que contienen secuencias promotoras de alfaherpesvirus.Info
- Publication number
- MX2021009161A MX2021009161A MX2021009161A MX2021009161A MX2021009161A MX 2021009161 A MX2021009161 A MX 2021009161A MX 2021009161 A MX2021009161 A MX 2021009161A MX 2021009161 A MX2021009161 A MX 2021009161A MX 2021009161 A MX2021009161 A MX 2021009161A
- Authority
- MX
- Mexico
- Prior art keywords
- seq
- nucleic acids
- recombinant nucleic
- alphaherpesvirus
- promoter sequences
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 5
- 108020004707 nucleic acids Proteins 0.000 title abstract 4
- 102000039446 nucleic acids Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
- A61K48/0058—Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962801524P | 2019-02-05 | 2019-02-05 | |
| US201962950848P | 2019-12-19 | 2019-12-19 | |
| PCT/US2020/016787 WO2020163475A1 (en) | 2019-02-05 | 2020-02-05 | Recombinant nucleic acids containing alphaherpesvirus promoter sequences |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2021009161A true MX2021009161A (es) | 2021-09-10 |
Family
ID=71947095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021009161A MX2021009161A (es) | 2019-02-05 | 2020-02-05 | Acidos nucleicos recombinantes que contienen secuencias promotoras de alfaherpesvirus. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US12551574B2 (enExample) |
| EP (1) | EP3921431A4 (enExample) |
| JP (2) | JP7658580B2 (enExample) |
| KR (1) | KR20210125014A (enExample) |
| CN (1) | CN113383082A (enExample) |
| AU (1) | AU2020218337A1 (enExample) |
| BR (1) | BR112021015281A2 (enExample) |
| CA (1) | CA3127019A1 (enExample) |
| MX (1) | MX2021009161A (enExample) |
| SG (1) | SG11202108111WA (enExample) |
| WO (1) | WO2020163475A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7658580B2 (ja) | 2019-02-05 | 2025-04-08 | ザ、トラスティーズ オブ プリンストン ユニバーシティ | アルファヘルペスウイルスプロモーター配列を含む組換え核酸 |
| US20250025575A1 (en) * | 2021-11-23 | 2025-01-23 | The Trustees Of Princeton University | Compositions and Methods for Cell-Specific Expression of Target Genes |
| WO2026032009A1 (en) * | 2024-08-06 | 2026-02-12 | Chinese Institute For Brain Research, Beijing (Cibr) | A microglia-specific regulatory element for aav-mediated transgene manipulation |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5352596A (en) * | 1992-09-11 | 1994-10-04 | The United States Of America As Represented By The Secretary Of Agriculture | Pseudorabies virus deletion mutants involving the EPO and LLT genes |
| US7341847B2 (en) * | 2003-04-02 | 2008-03-11 | Agency For Science, Technology And Research | Promoter construct for gene expression in neuronal cells |
| WO2005080581A2 (en) * | 2004-02-17 | 2005-09-01 | University Of Florida Research Foundation, Inc. | Insulated herpesvirus-derived gene expression cassettes for sustained and regulatable gene expression |
| EP2058401A1 (en) | 2007-10-05 | 2009-05-13 | Genethon | Widespread gene delivery to motor neurons using peripheral injection of AAV vectors |
| JP7090548B2 (ja) | 2016-01-29 | 2022-06-24 | ジリオン バイオテック ゲーエムベーハー | Ａａｖ系条件的発現系 |
| JP7658580B2 (ja) | 2019-02-05 | 2025-04-08 | ザ、トラスティーズ オブ プリンストン ユニバーシティ | アルファヘルペスウイルスプロモーター配列を含む組換え核酸 |
| US20250025575A1 (en) | 2021-11-23 | 2025-01-23 | The Trustees Of Princeton University | Compositions and Methods for Cell-Specific Expression of Target Genes |
-
2020
- 2020-02-05 JP JP2021545307A patent/JP7658580B2/ja active Active
- 2020-02-05 MX MX2021009161A patent/MX2021009161A/es unknown
- 2020-02-05 AU AU2020218337A patent/AU2020218337A1/en not_active Abandoned
- 2020-02-05 EP EP20753138.5A patent/EP3921431A4/en active Pending
- 2020-02-05 CA CA3127019A patent/CA3127019A1/en active Pending
- 2020-02-05 BR BR112021015281-4A patent/BR112021015281A2/pt not_active IP Right Cessation
- 2020-02-05 CN CN202080012381.9A patent/CN113383082A/zh active Pending
- 2020-02-05 KR KR1020217027131A patent/KR20210125014A/ko active Pending
- 2020-02-05 WO PCT/US2020/016787 patent/WO2020163475A1/en not_active Ceased
- 2020-02-05 US US17/426,389 patent/US12551574B2/en active Active
- 2020-02-05 SG SG11202108111WA patent/SG11202108111WA/en unknown
-
2024
- 2024-12-06 JP JP2024213389A patent/JP2025026584A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3921431A1 (en) | 2021-12-15 |
| CA3127019A1 (en) | 2020-08-13 |
| JP7658580B2 (ja) | 2025-04-08 |
| WO2020163475A1 (en) | 2020-08-13 |
| JP2025026584A (ja) | 2025-02-21 |
| JP2022518867A (ja) | 2022-03-16 |
| BR112021015281A2 (pt) | 2021-10-05 |
| EP3921431A4 (en) | 2022-12-14 |
| CN113383082A (zh) | 2021-09-10 |
| KR20210125014A (ko) | 2021-10-15 |
| US12551574B2 (en) | 2026-02-17 |
| SG11202108111WA (en) | 2021-08-30 |
| US20220378941A1 (en) | 2022-12-01 |
| AU2020218337A1 (en) | 2021-08-26 |
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