MX2021007233A - Nueva forma de sulfonamida de isoquinolina. - Google Patents

Nueva forma de sulfonamida de isoquinolina.

Info

Publication number
MX2021007233A
MX2021007233A MX2021007233A MX2021007233A MX2021007233A MX 2021007233 A MX2021007233 A MX 2021007233A MX 2021007233 A MX2021007233 A MX 2021007233A MX 2021007233 A MX2021007233 A MX 2021007233A MX 2021007233 A MX2021007233 A MX 2021007233A
Authority
MX
Mexico
Prior art keywords
isoquinolinesulfonamide
novel form
phenylpropylamino
propan
hydroxy
Prior art date
Application number
MX2021007233A
Other languages
English (en)
Inventor
Hiroyoshi Hidaka
Kengo Sumi
Takashi Izuhara
Original Assignee
D Western Therapeutics Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by D Western Therapeutics Inst Inc filed Critical D Western Therapeutics Inst Inc
Publication of MX2021007233A publication Critical patent/MX2021007233A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se proporciona un cristal estable de una sal de N-[(R)-1-{(S)-2-hidroxi-2-fenilpropilamino}propan-2-il]isoquinoli na-6-sulfonamida que tiene propiedades deseables para una sustancia farmacéutica, y más específicamente anhídrido de diclorhidrato de N-[(R)-1-{(S)-2-hidroxi-2-fenilpropilamino}propan -2-il]isoquinolina-6-sulfonamida.
MX2021007233A 2018-12-17 2019-12-16 Nueva forma de sulfonamida de isoquinolina. MX2021007233A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018235213 2018-12-17
PCT/JP2019/049099 WO2020129876A1 (ja) 2018-12-17 2019-12-16 イソキノリンスルホンアミドの新規な形態

Publications (1)

Publication Number Publication Date
MX2021007233A true MX2021007233A (es) 2021-07-15

Family

ID=71101331

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021007233A MX2021007233A (es) 2018-12-17 2019-12-16 Nueva forma de sulfonamida de isoquinolina.

Country Status (18)

Country Link
US (1) US11427546B2 (es)
EP (1) EP3901141B9 (es)
JP (1) JP7425482B2 (es)
KR (1) KR20210104729A (es)
CN (1) CN113195453B (es)
AU (1) AU2019402422A1 (es)
BR (1) BR112021011739A2 (es)
CA (1) CA3120751A1 (es)
DK (1) DK3901141T3 (es)
EA (1) EA202191339A1 (es)
ES (1) ES2972617T3 (es)
FI (1) FI3901141T3 (es)
HR (1) HRP20240372T1 (es)
MX (1) MX2021007233A (es)
PL (1) PL3901141T3 (es)
PT (1) PT3901141T (es)
SG (1) SG11202105739YA (es)
WO (1) WO2020129876A1 (es)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1370914A (en) 1971-07-06 1974-10-16 Ici Ltd Paint compositions
DE3943678C2 (de) * 1988-12-26 1999-11-25 Hiroyoshi Hidaka Isochinolinsulfonsäureamide, Verfahren zu deren Herstellung und diese Amide enthaltende pharmazeutische Zusammensetzung
US5340811A (en) * 1990-03-08 1994-08-23 Asahi Kasei Kogyo Kabushiki Kaisha Isoquinoline-or quinoline-sulfonamide derivative and a pharmaceutical composition comprising the same
JP2899953B2 (ja) * 1995-07-03 1999-06-02 旭化成工業株式会社 １−（５−イソキノリンスルホニル）ホモピペラジン塩酸塩１／２水和物
DE69606721T2 (de) 1995-07-03 2000-06-21 Asahi Chemical Ind 1-(5-isochinolinsulfonyl)homopiperazin hydrochlorid
MY139797A (en) * 2004-11-29 2009-10-30 Kowa Co (s)-(-)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1, 4-homopiperazine hydrochloride dihydrate
CN101730690B (zh) 2007-07-02 2013-01-16 旭化成制药株式会社 磺酰胺化合物及其结晶
PL2657227T3 (pl) * 2010-12-22 2016-09-30 Nowa podstawiona pochodna izochinoliny
JP5819705B2 (ja) 2011-11-09 2015-11-24 興和株式会社 イソキノリン誘導体塩酸塩無水物結晶

Also Published As

Publication number Publication date
PL3901141T3 (pl) 2024-05-27
SG11202105739YA (en) 2021-07-29
HRP20240372T1 (hr) 2024-06-07
CA3120751A1 (en) 2020-06-25
EP3901141B9 (en) 2024-06-19
EP3901141A1 (en) 2021-10-27
FI3901141T3 (fi) 2024-03-01
ES2972617T3 (es) 2024-06-13
CN113195453B (zh) 2024-04-30
AU2019402422A8 (en) 2021-07-01
DK3901141T3 (da) 2024-02-26
US20220017469A1 (en) 2022-01-20
US11427546B2 (en) 2022-08-30
PT3901141T (pt) 2024-03-04
WO2020129876A1 (ja) 2020-06-25
CN113195453A (zh) 2021-07-30
JPWO2020129876A1 (ja) 2021-11-04
KR20210104729A (ko) 2021-08-25
BR112021011739A2 (pt) 2021-08-31
EP3901141A4 (en) 2022-07-13
EP3901141B1 (en) 2024-02-07
JP7425482B2 (ja) 2024-01-31
EA202191339A1 (ru) 2021-08-27
AU2019402422A1 (en) 2021-06-17

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