MX2020014044A - Metodo para producir un derivado de (alfa)-azidoanilina o un derivado de (alfa), (alfa)'-diazida. - Google Patents

Metodo para producir un derivado de (alfa)-azidoanilina o un derivado de (alfa), (alfa)'-diazida.

Info

Publication number
MX2020014044A
MX2020014044A MX2020014044A MX2020014044A MX2020014044A MX 2020014044 A MX2020014044 A MX 2020014044A MX 2020014044 A MX2020014044 A MX 2020014044A MX 2020014044 A MX2020014044 A MX 2020014044A MX 2020014044 A MX2020014044 A MX 2020014044A
Authority
MX
Mexico
Prior art keywords
sup
group
substituted
formula
carbon atoms
Prior art date
Application number
MX2020014044A
Other languages
English (en)
Inventor
Masahiko Seki
Original Assignee
Tokuyama Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tokuyama Corp filed Critical Tokuyama Corp
Publication of MX2020014044A publication Critical patent/MX2020014044A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C07C247/16—Compounds containing azido groups with azido groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C247/18—Compounds containing azido groups with azido groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J27/00—Catalysts comprising the elements or compounds of halogens, sulfur, selenium, tellurium, phosphorus or nitrogen; Catalysts comprising carbon compounds
    • B01J27/02—Sulfur, selenium or tellurium; Compounds thereof
    • B01J27/053—Sulfates
    • B01J27/055—Sulfates with alkali metals, copper, gold or silver
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/04—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides containing carboxylic acids or their salts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B61/00—Other general methods
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C07C247/16—Compounds containing azido groups with azido groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)

Abstract

Se proporciona un método para producir un derivado de a-azidoanilina o un derivado de a,a'-diazida usando un derivado de anilina a manera de material de partida. La presente invención incluye un método para producir un derivado de a-azidoanilina o un derivado de a,a'-diazida representado por la Fórmula (2), que incluye el paso de: poner en contacto un derivado de anilina representado por la Fórmula (1) con un agente azidante en presencia de agua, un persulfato y un compuesto de cobre en la Fórmula (1) R1 a R5 son cada uno indistintamente un átomo de hidrógeno, un átomo de halógeno, un grupo nitro, un grupo ciano, un grupo alquilo sustituido o no sustituido que tiene 1 a 12 átomos de carbono, un grupo alcoxilo sustituido o no sustituido que tiene 1 a 12 átomos de carbono, un grupo aralquilo sustituido o no sustituido que tiene 7 a 14 átomos de carbono, un grupo arilo sustituido o no sustituido que tiene 2 a 13 átomos de carbono, un grupo alcoxicarbonilo sustituido o no sustituido que tiene 2 a 7 átomos de carbono, un grupo carbonilo sustituido o no sustituido que tiene 1 a 20 átomos de carbono, u opcionalmente forman un anillo hidrocarburo alifático, un anillo aromático o un anillo heterocíclico conjuntamente con un grupo adyacente. En la Fórmula (2), R1 a R3 y R5 tienen un significado igual que el de R1 a R3 y R5 en la Fórmula (1), y R4 es un grupo azido (N3) o tiene un significado igual que el de R4 en la Fórmula (1). (ver Fórmulas).
MX2020014044A 2018-06-28 2019-06-12 Metodo para producir un derivado de (alfa)-azidoanilina o un derivado de (alfa), (alfa)'-diazida. MX2020014044A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018122811 2018-06-28
PCT/JP2019/023333 WO2020004043A1 (ja) 2018-06-28 2019-06-12 α－アジドアニリン誘導体又はα，α'－ジアジド誘導体の製造方法

Publications (1)

Publication Number Publication Date
MX2020014044A true MX2020014044A (es) 2021-03-09

Family

ID=68986442

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020014044A MX2020014044A (es) 2018-06-28 2019-06-12 Metodo para producir un derivado de (alfa)-azidoanilina o un derivado de (alfa), (alfa)'-diazida.

Country Status (11)

Country Link
US (1) US20210246108A1 (es)
EP (1) EP3816151A1 (es)
JP (1) JPWO2020004043A1 (es)
KR (1) KR20210025517A (es)
CN (1) CN112262124A (es)
AU (1) AU2019292883A1 (es)
CA (1) CA3104437A1 (es)
MX (1) MX2020014044A (es)
SG (1) SG11202012760SA (es)
TW (1) TW202005951A (es)
WO (1) WO2020004043A1 (es)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1778650A4 (en) 2004-07-28 2009-12-02 Reddys Lab Ltd Dr PROCESS OF MANUFACTURING CANDÉSARTAN CILEXÉTIL
BR112013002729A2 (pt) 2010-08-04 2016-05-31 Bristol Myers Squibb Co inibidores de vírus de hepatite c
JP2016028016A (ja) * 2012-12-12 2016-02-25 大日本住友製薬株式会社 オキサジアゾール誘導体とその医薬用途
JP6402393B2 (ja) 2014-05-15 2018-10-10 ジェイファーマ株式会社 抗悪性腫瘍剤組成物
CN106478594B (zh) * 2016-08-26 2019-04-09 浙江工业大学 一种荧光染料及其合成与制备荧光探针的应用

Also Published As

Publication number Publication date
KR20210025517A (ko) 2021-03-09
CA3104437A1 (en) 2020-01-02
TW202005951A (zh) 2020-02-01
AU2019292883A1 (en) 2021-01-14
CN112262124A (zh) 2021-01-22
SG11202012760SA (en) 2021-01-28
JPWO2020004043A1 (ja) 2021-08-05
WO2020004043A1 (ja) 2020-01-02
US20210246108A1 (en) 2021-08-12
EP3816151A1 (en) 2021-05-05

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