MX2020012933A - Metodo de produccion biocatalitica de compuestos terpenicos. - Google Patents

Metodo de produccion biocatalitica de compuestos terpenicos.

Info

Publication number
MX2020012933A
MX2020012933A MX2020012933A MX2020012933A MX2020012933A MX 2020012933 A MX2020012933 A MX 2020012933A MX 2020012933 A MX2020012933 A MX 2020012933A MX 2020012933 A MX2020012933 A MX 2020012933A MX 2020012933 A MX2020012933 A MX 2020012933A
Authority
MX
Mexico
Prior art keywords
terpene compounds
production
novel
compounds
biocatalytic production
Prior art date
Application number
MX2020012933A
Other languages
English (en)
Inventor
Michel Schalk
Letizia ROCCI
Escalante Daniel Solis
Original Assignee
Firmenich & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Firmenich & Cie filed Critical Firmenich & Cie
Publication of MX2020012933A publication Critical patent/MX2020012933A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/07—Diphosphoric monoester hydrolases (3.1.7)
    • C12Y301/07003—Monoterpenyl-diphosphatase (3.1.7.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

En el presente documento se proporcionan métodos biocatalíticos para producir compuestos terpénicos aplicando un nuevo tipo de enzima de fosfatasa. El método permite la síntesis completamente bioquímica de compuestos terpénicos, tales como por ejemplo el copalol y labdendiol, y derivados de los mismos, que sirven como compuestos intermedios valiosos para la producción de ingredientes de perfumería, tales como por ejemplo el ambrox. También se proporcionan nuevos procesos de etapas múltiples completamente bioquímicos para la producción de tales compuestos, así como nuevas enzimas de fosfatasa y mutantes y variantes derivadas de los mismos.
MX2020012933A 2018-07-10 2019-07-10 Metodo de produccion biocatalitica de compuestos terpenicos. MX2020012933A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18182783 2018-07-10
PCT/EP2019/068609 WO2020011883A1 (en) 2018-07-10 2019-07-10 Method for biocatalytic production of terpene compounds

Publications (1)

Publication Number Publication Date
MX2020012933A true MX2020012933A (es) 2021-02-15

Family

ID=62916485

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020012933A MX2020012933A (es) 2018-07-10 2019-07-10 Metodo de produccion biocatalitica de compuestos terpenicos.

Country Status (7)

Country Link
US (1) US11214775B2 (es)
EP (1) EP3821023A1 (es)
JP (2) JP7406511B2 (es)
CN (1) CN112334581A (es)
BR (1) BR112020024197A2 (es)
MX (1) MX2020012933A (es)
WO (1) WO2020011883A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230193328A1 (en) * 2020-03-06 2023-06-22 Board Of Trustees Of Michigan State University Method to produce the anti-microbial diterpenoid leubethanol and related serrulatane-type diterpenes
WO2023288293A1 (en) * 2021-07-16 2023-01-19 Amyris, Inc. Novel enzymes for the production of e-copalol

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6303654B1 (en) 1998-03-12 2001-10-16 Wisconsin Alumni Research Foundation Acyclic monoterpenoid derivatives
DE19931847A1 (de) 1999-07-09 2001-01-11 Basf Ag Immobilisierte Lipase
DE10019380A1 (de) 2000-04-19 2001-10-25 Basf Ag Verfahren zur Herstellung von kovalent gebundenen biologisch aktiven Stoffen an Polyurethanschaumstoffen sowie Verwendung der geträgerten Polyurethanschaumstoffe für chirale Synthesen
CN102016051B (zh) 2008-01-29 2014-05-28 弗门尼舍有限公司 生产香紫苏醇的方法
GB201601249D0 (en) 2016-01-22 2016-03-09 Firmenich & Cie Production of manool
KR102636404B1 (ko) 2016-06-15 2024-02-13 경상국립대학교산학협력단 터펜 알코올 또는 그 유도체의 제조 방법
CN107119001B (zh) 2017-04-26 2019-07-19 福建师范大学 基因工程化类球红细菌及其制备方法和法尼醇的生产方法

Also Published As

Publication number Publication date
JP2021524261A (ja) 2021-09-13
US20210222138A1 (en) 2021-07-22
US11214775B2 (en) 2022-01-04
JP7406511B2 (ja) 2023-12-27
EP3821023A1 (en) 2021-05-19
WO2020011883A1 (en) 2020-01-16
JP2024029002A (ja) 2024-03-05
BR112020024197A2 (pt) 2021-02-17
CN112334581A (zh) 2021-02-05

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