MX2020011804A - Vacunas contra el virus de la hepatitis b (hbv) y usos de las mismas. - Google Patents

Vacunas contra el virus de la hepatitis b (hbv) y usos de las mismas.

Info

Publication number
MX2020011804A
MX2020011804A MX2020011804A MX2020011804A MX2020011804A MX 2020011804 A MX2020011804 A MX 2020011804A MX 2020011804 A MX2020011804 A MX 2020011804A MX 2020011804 A MX2020011804 A MX 2020011804A MX 2020011804 A MX2020011804 A MX 2020011804A
Authority
MX
Mexico
Prior art keywords
hbv
virus
hepatitis
vectors
vaccines
Prior art date
Application number
MX2020011804A
Other languages
English (en)
Inventor
Soumitra Roy
Helen Horton
Pooter Dorien De
Daniel Boden
Jean- Marc Edmond Fernand Marie NEEFS
Original Assignee
Janssen Sciences Ireland Unlimited Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Sciences Ireland Unlimited Co filed Critical Janssen Sciences Ireland Unlimited Co
Publication of MX2020011804A publication Critical patent/MX2020011804A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Abstract

Se describen polinucleótidos que codifican para el antígeno de core y el antígeno de polimerasa del virus de la hepatitis B (HBV), y combinaciones relacionadas; se describen también vectores, tales como plásmidos de ADN o vectores virales, que expresan los antígenos de core y polimerasa de HBV, y composiciones inmunógenas que contienen los vectores de expresión; se describen también métodos para inducir una respuesta inmune contra el HBV o para tratar una enfermedad inducida por el HBV, en particular en individuos que tienen infección crónica por HBV, usando las composiciones inmunógenas.
MX2020011804A 2017-12-19 2020-07-13 Vacunas contra el virus de la hepatitis b (hbv) y usos de las mismas. MX2020011804A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762607426P 2017-12-19 2017-12-19
IB2017058142 2017-12-19

Publications (1)

Publication Number Publication Date
MX2020011804A true MX2020011804A (es) 2020-12-07

Family

ID=65199441

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2020006480A MX2020006480A (es) 2017-12-19 2018-12-18 Vacunas contra el virus de la hepatitis b (hbv) y usos de las mismas.
MX2020011802A MX2020011802A (es) 2017-12-19 2020-07-13 Vacunas contra el virus de la hepatitis b (hbv) y usos de las mismas.
MX2020011804A MX2020011804A (es) 2017-12-19 2020-07-13 Vacunas contra el virus de la hepatitis b (hbv) y usos de las mismas.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2020006480A MX2020006480A (es) 2017-12-19 2018-12-18 Vacunas contra el virus de la hepatitis b (hbv) y usos de las mismas.
MX2020011802A MX2020011802A (es) 2017-12-19 2020-07-13 Vacunas contra el virus de la hepatitis b (hbv) y usos de las mismas.

Country Status (15)

Country Link
EP (2) EP3727445B1 (es)
JP (1) JP7317017B2 (es)
KR (1) KR20200101416A (es)
CN (1) CN111836641A (es)
AU (1) AU2018389787A1 (es)
BR (1) BR112020011976A2 (es)
CA (1) CA3086327A1 (es)
ES (1) ES2963179T3 (es)
IL (1) IL275427B2 (es)
JO (1) JOP20200153A1 (es)
MA (1) MA51311A (es)
MX (3) MX2020006480A (es)
PH (1) PH12020550924A1 (es)
SG (1) SG11202005895QA (es)
WO (1) WO2019123252A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017347725B2 (en) 2016-10-17 2024-01-04 Janssen Pharmaceuticals, Inc. Recombinant virus replicon systems and uses thereof
CA3045650A1 (en) 2016-12-05 2018-06-14 Synthetic Genomics, Inc. Compositions and methods for enhancing gene expression
EA202091517A1 (ru) 2017-12-19 2020-11-03 Янссен Сайенсиз Айрлэнд Анлимитед Компани Способы и устройство для доставки вакцин против вируса гепатита b (hbv)
US11021692B2 (en) 2017-12-19 2021-06-01 Janssen Sciences Ireland Unlimited Company Hepatitis B virus (HBV) vaccines and uses thereof
JP2021511318A (ja) 2018-01-19 2021-05-06 ヤンセン ファーマシューティカルズ，インコーポレーテッド 組換えレプリコン系を使用する免疫応答の誘導および増強
US20220324916A1 (en) * 2019-06-18 2022-10-13 Janssen Sciences Ireland Unlimited Company Hepatitis B Virus (HBV) Vaccines and Uses Thereof
US20220313815A1 (en) * 2019-06-20 2022-10-06 Janssen Sciences Ireland Unlimited Company Self-replicating rna molecules for hepatitis b virus (hbv) vaccines and uses thereof
WO2022133230A1 (en) * 2020-12-18 2022-06-23 Janssen Pharmaceuticals, Inc. Combination therapy for treating hepatitis b virus infection
WO2023283745A1 (en) * 2021-07-16 2023-01-19 Mcmaster University Viral vaccine

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988007089A1 (en) 1987-03-18 1988-09-22 Medical Research Council Altered antibodies
US5273525A (en) 1992-08-13 1993-12-28 Btx Inc. Injection and electroporation apparatus for drug and gene delivery
NZ271531A (en) * 1993-08-02 1998-02-26 Scripps Research Inst Peptide which induces cytotoxic t lymphocyte responses to heptatitis b antigens
US6041252A (en) 1995-06-07 2000-03-21 Ichor Medical Systems Inc. Drug delivery system and method
US6261281B1 (en) 1997-04-03 2001-07-17 Electrofect As Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells
EA002087B1 (ru) 1997-04-03 2001-12-24 Электрофект Ас Способ введения фармацевтических препаратов и нуклеиновых кислот в скелетную мышцу
US5873849A (en) 1997-04-24 1999-02-23 Ichor Medical Systems, Inc. Electrodes and electrode arrays for generating electroporation inducing electrical fields
US6117660A (en) 1997-06-10 2000-09-12 Cytopulse Sciences, Inc. Method and apparatus for treating materials with electrical fields having varying orientations
CZ299473B6 (cs) 1997-06-30 2008-08-06 Rhone-Poulenc Rorer S. A. Nukleová kyselina a elektrické pole jako sdruženýprodukt pro prenos nukleové kyseliny do bunek prícne pruhovaného svalstva
US6697669B2 (en) 1998-07-13 2004-02-24 Genetronics, Inc. Skin and muscle-targeted gene therapy by pulsed electrical field
US6319901B1 (en) 1998-10-15 2001-11-20 Ichor Medical Systems, Inc. Methods for prolonging cell membrane permeability
RU2295536C2 (ru) * 2001-02-05 2007-03-20 Стрессджен Байотекнолоджиз Корп. Композиции на основе белка вируса гепатита в и стрессового белка и их применение
US8209006B2 (en) 2002-03-07 2012-06-26 Vgx Pharmaceuticals, Inc. Constant current electroporation device and methods of use
US7245963B2 (en) 2002-03-07 2007-07-17 Advisys, Inc. Electrode assembly for constant-current electroporation and use
US6912417B1 (en) 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
US7328064B2 (en) 2002-07-04 2008-02-05 Inovio As Electroporation device and injection apparatus
ES2695235T3 (es) 2004-03-08 2019-01-02 Ichor Medical Systems Inc Aparato mejorado para el suministro, mediado eléctricamente, de agentes terapéuticos
SG175627A1 (en) 2006-10-17 2011-11-28 Vgx Pharmaceuticals Inc Electroporation devices and methods of using same forelectroporation of cells in mammals
KR100836745B1 (ko) * 2007-01-31 2008-06-10 (주)두비엘 Ｈｂｖ 백신 및 그의 제조 방법
AU2012214394B2 (en) * 2011-02-12 2016-08-11 Globeimmune, Inc. Yeast-based therapeutic for chronic hepatitis B infection
TWI623618B (zh) * 2011-07-12 2018-05-11 傳斯堅公司 Ｈｂｖ聚合酶突變體
JP6910075B2 (ja) 2016-03-28 2021-07-28 イコル メディカル システムズ，インク． 治療薬の送達のための方法および装置
US11324819B2 (en) * 2016-04-06 2022-05-10 University Of Washington Therapeutic vaccine for Hepatitis b virus (HBV) using the HBV core antigen

Also Published As

Publication number Publication date
MX2020006480A (es) 2020-09-22
CN111836641A (zh) 2020-10-27
KR20200101416A (ko) 2020-08-27
MA51311A (fr) 2020-10-28
EP4272833A2 (en) 2023-11-08
EP3727445A1 (en) 2020-10-28
SG11202005895QA (en) 2020-07-29
WO2019123252A1 (en) 2019-06-27
CA3086327A1 (en) 2019-06-27
IL275427A (en) 2020-08-31
BR112020011976A2 (pt) 2020-11-24
EP4272833A3 (en) 2024-01-10
JOP20200153A1 (ar) 2022-10-30
PH12020550924A1 (en) 2021-05-31
JP7317017B2 (ja) 2023-07-28
EP3727445C0 (en) 2023-08-16
ES2963179T3 (es) 2024-03-25
IL275427B2 (en) 2024-04-01
EP3727445B1 (en) 2023-08-16
MX2020011802A (es) 2020-12-07
JP2021509107A (ja) 2021-03-18
IL275427B1 (en) 2023-12-01
AU2018389787A1 (en) 2020-06-25

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