MX2020006072A - Métodos y composiciones relacionados con cpf1 para la edición genica. - Google Patents

Métodos y composiciones relacionados con cpf1 para la edición genica.

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Publication number
MX2020006072A
MX2020006072A MX2020006072A MX2020006072A MX2020006072A MX 2020006072 A MX2020006072 A MX 2020006072A MX 2020006072 A MX2020006072 A MX 2020006072A MX 2020006072 A MX2020006072 A MX 2020006072A MX 2020006072 A MX2020006072 A MX 2020006072A
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Mexico
Prior art keywords
cpf1
compositions
related methods
gene editing
editing
Prior art date
Application number
MX2020006072A
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English (en)
Inventor
Jennifer Gori
John Zuris
Hariharan Jayaram
Original Assignee
Editas Medicine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Editas Medicine Inc filed Critical Editas Medicine Inc
Publication of MX2020006072A publication Critical patent/MX2020006072A/es

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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N9/22—Ribonucleases RNAses, DNAses
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    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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    • A61K39/4643—Vertebrate antigens
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPRs]
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites

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Abstract

La presente divulgación se refiere a métodos y componentes relacionados con CRISPR/Cpf1 para editar una secuencia de ácido nucleico diana, y/o modular la expresión de una secuencia de ácido nucleico diana, así como a métodos y composiciones para evaluar dicha edición y/o modulación de la expresión.
MX2020006072A 2017-12-11 2018-12-11 Métodos y composiciones relacionados con cpf1 para la edición genica. MX2020006072A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762597118P 2017-12-11 2017-12-11
US201862623501P 2018-01-29 2018-01-29
US201862664905P 2018-04-30 2018-04-30
US201862746494P 2018-10-16 2018-10-16
PCT/US2018/065032 WO2019118516A1 (en) 2017-12-11 2018-12-11 Cpf1-related methods and compositions for gene editing

Publications (1)

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MX2020006072A true MX2020006072A (es) 2020-08-24

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US (1) US20200299661A1 (es)
EP (1) EP3724326A1 (es)
JP (2) JP2021505187A (es)
KR (1) KR20200097760A (es)
CN (1) CN111712569A (es)
AU (1) AU2018383712A1 (es)
CA (1) CA3085338A1 (es)
MX (1) MX2020006072A (es)
WO (1) WO2019118516A1 (es)

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WO2019118516A1 (en) 2019-06-20
AU2018383712A1 (en) 2020-07-02
JP2021505187A (ja) 2021-02-18
EP3724326A1 (en) 2020-10-21
KR20200097760A (ko) 2020-08-19
CA3085338A1 (en) 2019-06-20
US20200299661A1 (en) 2020-09-24
CN111712569A (zh) 2020-09-25
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