MX2018005392A - Acidos nucleicos modificados dirigidos a acidos nucleicos. - Google Patents

Acidos nucleicos modificados dirigidos a acidos nucleicos.

Info

Publication number
MX2018005392A
MX2018005392A MX2018005392A MX2018005392A MX2018005392A MX 2018005392 A MX2018005392 A MX 2018005392A MX 2018005392 A MX2018005392 A MX 2018005392A MX 2018005392 A MX2018005392 A MX 2018005392A MX 2018005392 A MX2018005392 A MX 2018005392A
Authority
MX
Mexico
Prior art keywords
polynucleotide sequences
engineered
nucleic
acid targeting
form scaffolds
Prior art date
Application number
MX2018005392A
Other languages
English (en)
Inventor
Paul May Andrew
Daniel Donohoue Paul
Original Assignee
Caribou Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Caribou Biosciences Inc filed Critical Caribou Biosciences Inc
Publication of MX2018005392A publication Critical patent/MX2018005392A/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPRs]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/51—Physical structure in polymeric form, e.g. multimers, concatemers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/52—Physical structure branched
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La presente descripción proporciona secuencias de polinucleótidos modificadas que forman andamios y complejos de nucleoproteína que comprenden dichas secuencias de polinucleótidos modificadas que forman andamios y proteínas de unión a ácidos nucleicos. Se describen secuencias de ácidos nucleicos que codifican las secuencias de polinucleótidos modificadas que forman andamios, así como cassettes de expresión, vectores y células que comprenden dichas secuencias de polinucleótidos. También se describe una variedad de métodos para hacer y usar las secuencias de polinucleótidos modificadas que forman andamios.
MX2018005392A 2015-12-04 2016-12-02 Acidos nucleicos modificados dirigidos a acidos nucleicos. MX2018005392A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562263232P 2015-12-04 2015-12-04
PCT/US2016/064860 WO2017096328A1 (en) 2015-12-04 2016-12-02 Engineered nucleic-acid targeting nucleic acids

Publications (1)

Publication Number Publication Date
MX2018005392A true MX2018005392A (es) 2019-05-30

Family

ID=57750577

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018005392A MX2018005392A (es) 2015-12-04 2016-12-02 Acidos nucleicos modificados dirigidos a acidos nucleicos.

Country Status (18)

Country Link
US (4) US9771600B2 (es)
EP (2) EP3371310B1 (es)
JP (1) JP6707133B2 (es)
KR (1) KR102093570B1 (es)
CN (1) CN108473981B (es)
AU (2) AU2016363024B2 (es)
BR (1) BR112018010429A2 (es)
CA (1) CA3004757C (es)
DK (1) DK3371310T3 (es)
ES (1) ES2735773T3 (es)
HK (1) HK1252755B (es)
IL (1) IL259148B (es)
MX (1) MX2018005392A (es)
NZ (2) NZ756843A (es)
RU (1) RU2018117360A (es)
SG (1) SG11201803593QA (es)
WO (1) WO2017096328A1 (es)
ZA (1) ZA201802968B (es)

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US11499151B2 (en) 2017-04-28 2022-11-15 Editas Medicine, Inc. Methods and systems for analyzing guide RNA molecules
US11584955B2 (en) * 2017-07-14 2023-02-21 Shanghai Tolo Biotechnology Company Limited Application of Cas protein, method for detecting target nucleic acid molecule and kit
WO2019014564A1 (en) 2017-07-14 2019-01-17 Editas Medicine, Inc. SYSTEMS AND METHODS OF TARGETED INTEGRATION AND GENOME EDITING AND DETECTION THEREOF WITH INTEGRATED PRIMING SITES
WO2019041296A1 (zh) * 2017-09-01 2019-03-07 上海科技大学 一种碱基编辑系统及方法
WO2019051428A1 (en) * 2017-09-11 2019-03-14 The Regents Of The University Of California CAS9 ANTIBODY MEDIA ADMINISTRATION TO MAMMALIAN CELLS
US20210093679A1 (en) 2018-02-05 2021-04-01 Novome Biotechnologies, Inc. Engineered gut microbes and uses thereof
WO2019157326A1 (en) 2018-02-08 2019-08-15 Zymergen Inc. Genome editing using crispr in corynebacterium
JP2021523745A (ja) 2018-05-16 2021-09-09 シンテゴ コーポレイション ガイドｒｎａ設計および使用のための方法およびシステム
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CN109517722B (zh) * 2018-09-28 2022-04-01 德拜至臻医学科技(杭州)有限公司 一种捕获特定微量细胞的装置及其制作和使用方法
AU2019357042A1 (en) 2018-10-12 2021-05-27 Theradaptive, Inc. Polypeptides including a beta-tricalcium phosphate-binding sequence and uses thereof
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CN114540325B (zh) * 2022-01-17 2022-12-09 广州医科大学 靶向dna去甲基化的方法、融合蛋白及其应用
CN116377104B (zh) * 2022-11-14 2024-01-12 海南省农业科学院蔬菜研究所 一种快菜高温胁迫内参基因及其引物及应用

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Also Published As

Publication number Publication date
CA3004757C (en) 2020-07-21
RU2018117360A3 (es) 2020-01-09
US20170159073A1 (en) 2017-06-08
KR102093570B1 (ko) 2020-03-25
NZ756843A (en) 2021-07-30
US20180119173A1 (en) 2018-05-03
SG11201803593QA (en) 2018-06-28
US10100333B2 (en) 2018-10-16
BR112018010429A2 (pt) 2018-11-27
EP3564371B1 (en) 2020-05-27
US9771600B2 (en) 2017-09-26
US11505808B2 (en) 2022-11-22
AU2016363024A1 (en) 2018-05-17
IL259148B (en) 2021-08-31
HK1252755A1 (zh) 2019-05-31
ES2735773T3 (es) 2019-12-20
HK1252755B (zh) 2020-02-07
IL259148A (en) 2018-07-31
NZ742040A (en) 2019-08-30
AU2019240724A1 (en) 2019-10-24
AU2016363024B2 (en) 2020-01-30
JP6707133B2 (ja) 2020-06-10
CN108473981B (zh) 2022-04-12
US20190100775A1 (en) 2019-04-04
DK3371310T3 (da) 2019-08-05
CN108473981A (zh) 2018-08-31
EP3371310B1 (en) 2019-05-01
JP2019500867A (ja) 2019-01-17
EP3371310A1 (en) 2018-09-12
US9970029B1 (en) 2018-05-15
AU2019240724B2 (en) 2021-02-18
US20180251788A1 (en) 2018-09-06
CA3004757A1 (en) 2017-06-08
RU2018117360A (ru) 2020-01-09
EP3564371A1 (en) 2019-11-06
KR20180085795A (ko) 2018-07-27
ZA201802968B (en) 2019-02-27
WO2017096328A1 (en) 2017-06-08

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