MX2020004683A - Metodos de inmunoterapia oral. - Google Patents

Metodos de inmunoterapia oral.

Info

Publication number
MX2020004683A
MX2020004683A MX2020004683A MX2020004683A MX2020004683A MX 2020004683 A MX2020004683 A MX 2020004683A MX 2020004683 A MX2020004683 A MX 2020004683A MX 2020004683 A MX2020004683 A MX 2020004683A MX 2020004683 A MX2020004683 A MX 2020004683A
Authority
MX
Mexico
Prior art keywords
peanut
peanut allergy
subject
treatment
methods
Prior art date
Application number
MX2020004683A
Other languages
English (en)
Inventor
Stephen G Dilly
Original Assignee
Aimmune Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aimmune Therapeutics Inc filed Critical Aimmune Therapeutics Inc
Publication of MX2020004683A publication Critical patent/MX2020004683A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente descripción se refiere a métodos mejorados de inmunoterapia oral para tratar alergias alimentarias. y particularmente alergia al cacahuate. Los biomarcadores. tales como un nivel de IgEs específicas de cacahuate y/o IgG4 especifica de cacahuate se usan mediante los métodos descritos en este documento. Dichos métodos incluyen un método para tratar a un sujeto para una alergia al cacahuate. métodos para evaluar la idoneidad de un tratamiento para una alergia al cacahuate. un método para evaluar un síntoma en un sujeto durante el curso del tratamiento de una alergia al cacahuate, un método para monitorizar el tratamiento para una alergia al cacahuate en un sujeto. un método para reducir el riesgo o la incidencia de un evento adverso en un sujeto que recibe tratamiento para una alergia al cacahuate, un método para ajustar una dosis de una composición alérgena de cacahuate y un método para evaluar una probabilidad de una reacción alérgica que requiera la administración de epinefrina a un sujeto que recibe tratamiento para una alergia al cacahuate.
MX2020004683A 2017-11-02 2018-11-01 Metodos de inmunoterapia oral. MX2020004683A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762580999P 2017-11-02 2017-11-02
US201862631406P 2018-02-15 2018-02-15
US201862637903P 2018-03-02 2018-03-02
US201862674478P 2018-05-21 2018-05-21
PCT/US2018/058777 WO2019089978A1 (en) 2017-11-02 2018-11-01 Methods of oral immunotherapy

Publications (1)

Publication Number Publication Date
MX2020004683A true MX2020004683A (es) 2020-08-13

Family

ID=66332382

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020004683A MX2020004683A (es) 2017-11-02 2018-11-01 Metodos de inmunoterapia oral.

Country Status (8)

Country Link
US (2) US11369676B2 (es)
EP (1) EP3703743A4 (es)
KR (1) KR20200083526A (es)
CN (1) CN111344010A (es)
AU (1) AU2018358125A1 (es)
CA (1) CA3080601A1 (es)
MX (1) MX2020004683A (es)
WO (1) WO2019089978A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105101994B (zh) 2013-03-14 2018-10-12 艾慕恩治疗公司 用于口服脱敏的花生制剂的制备
EP3185900A4 (en) 2014-08-25 2018-05-02 Aimmune Therapeutics, Inc. Egg protein formulations and methods of manufacture thereof
CN111629721A (zh) 2017-12-06 2020-09-04 百乐吉公司 用于减少过敏反应的组合物和方法
EP3829632A4 (en) 2018-07-27 2022-05-04 Société des Produits Nestlé S.A. SYSTEMS AND METHODS FOR DELIVERING UNIT DOSES OF ORAL IMMUNOTHERAPY
WO2020100024A1 (en) * 2018-11-12 2020-05-22 Murdoch Childrens Research Institute Method and system
CN113891722A (zh) * 2018-12-20 2022-01-04 爱沐疗法公司 用于漏服剂量的花生口服免疫疗法给药计划表
AU2020276213A1 (en) 2019-05-10 2021-10-28 Société des Produits Nestlé S.A. Methods for improving the quality of life of a patient with a peanut allergy
JP2023506028A (ja) * 2019-12-23 2023-02-14 プロタ セラピューティクス ピーティワイ リミテッド 医薬組成物
WO2022089595A1 (en) * 2020-10-30 2022-05-05 Oneness Biotech Co., Ltd. Biomarkers for ige-mediated diseases
WO2022182789A1 (en) * 2021-02-24 2022-09-01 Alladapt Immunotherapeutics, Inc. Methods of treating allergies
WO2023200316A1 (ko) * 2022-04-15 2023-10-19 사회복지법인 삼성생명공익재단 경구면역요법을 이용한 식품알레르기 치료서비스 제공방법, 이를 구현하기 위한 기록매체에 저장된 컴퓨터 프로그램 및 시스템

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3809767A (en) 1969-05-12 1974-05-07 Griffith Laboratories Methods of making vegetable protein concentrates
DK1272213T3 (da) 2000-04-06 2006-07-10 Seer Pharmaceuticals Llc Mikrobielt afgivelsessystem
CA2559458A1 (en) 2004-03-19 2005-10-06 Xiu-Min Li Herbal therapy for the treatment of food allergy
US20090111702A1 (en) * 2004-04-06 2009-04-30 Mount Sinai School Of Medicine Office Of Industrial Liason Methods of determining allergen response using microarray immunoassay techniques
CN102159201A (zh) 2008-12-19 2011-08-17 莫茨药物股份两合公司 用于治疗肥大细胞介导的疾病的1-氨基-烷基环己烷衍生物
AR081776A1 (es) 2010-06-30 2012-10-17 Novartis Ag Composiciones farmaceuticas que comprenden monohidrato de lactato de 4-amino-5-fluoro-3-[6-(4-metil-piperazin-1-il)-1h-bencimidazol-2-il]-1h-quinolin-2-ona, proceso para la produccion de la composicion
GB201104537D0 (en) 2011-03-17 2011-05-04 Cambridge Entpr Ltd Treatment for peanut allergy
WO2014159609A1 (en) * 2013-03-14 2014-10-02 Allergen Research Corporation Peanut formulations and uses thereof
CN105101994B (zh) 2013-03-14 2018-10-12 艾慕恩治疗公司 用于口服脱敏的花生制剂的制备
EP3185900A4 (en) 2014-08-25 2018-05-02 Aimmune Therapeutics, Inc. Egg protein formulations and methods of manufacture thereof
SG10201913846XA (en) 2017-01-13 2020-03-30 Aimmune Therapeutics Inc Methods of manufacture of nut flours and formulations for oral immunotherapy

Also Published As

Publication number Publication date
US20220288196A1 (en) 2022-09-15
US20190167785A1 (en) 2019-06-06
CN111344010A (zh) 2020-06-26
CA3080601A1 (en) 2019-05-09
KR20200083526A (ko) 2020-07-08
AU2018358125A1 (en) 2020-05-14
EP3703743A4 (en) 2021-12-08
WO2019089978A1 (en) 2019-05-09
JP2021501763A (ja) 2021-01-21
EP3703743A1 (en) 2020-09-09
US11369676B2 (en) 2022-06-28

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