MX2020002229A - Metodos para aumentar y/o estabilizar la funcion cardiaca en pacientes con enfermedad de fabry. - Google Patents
Metodos para aumentar y/o estabilizar la funcion cardiaca en pacientes con enfermedad de fabry.Info
- Publication number
- MX2020002229A MX2020002229A MX2020002229A MX2020002229A MX2020002229A MX 2020002229 A MX2020002229 A MX 2020002229A MX 2020002229 A MX2020002229 A MX 2020002229A MX 2020002229 A MX2020002229 A MX 2020002229A MX 2020002229 A MX2020002229 A MX 2020002229A
- Authority
- MX
- Mexico
- Prior art keywords
- enhancing
- methods
- patients
- cardiac function
- fabry disease
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 208000024720 Fabry Disease Diseases 0.000 title abstract 2
- 230000002708 enhancing effect Effects 0.000 title abstract 2
- 230000004217 heart function Effects 0.000 title abstract 2
- 230000000087 stabilizing effect Effects 0.000 title abstract 2
- 239000012458 free base Substances 0.000 abstract 1
- LXBIFEVIBLOUGU-DPYQTVNSSA-N migalastat Chemical compound OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O LXBIFEVIBLOUGU-DPYQTVNSSA-N 0.000 abstract 1
- 229950007469 migalastat Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Se proveen métodos para el tratamiento de la enfermedad de Fabry en un paciente; ciertos métodos se relacionan con el tratamiento de pacientes con enfermedad de Fabry que se han sometido o que no se han sometido previamente a una ERT; ciertos métodos comprenden administrar al paciente entre aproximadamente 100 mg y aproximadamente 150 mg equivalentes de base libre de migalastat para aumentar y/o estabilizar la función cardiaca.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762550984P | 2017-08-28 | 2017-08-28 | |
| PCT/US2018/048257 WO2019046244A1 (en) | 2017-08-28 | 2018-08-28 | METHODS FOR ENHANCING AND / OR STABILIZING CARDIAC FUNCTION IN PATIENTS WITH FABRY DISEASE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2020002229A true MX2020002229A (es) | 2020-07-20 |
Family
ID=63528948
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2020002229A MX2020002229A (es) | 2017-08-28 | 2018-08-28 | Metodos para aumentar y/o estabilizar la funcion cardiaca en pacientes con enfermedad de fabry. |
| MX2023005628A MX2023005628A (es) | 2017-08-28 | 2020-02-27 | Metodos para aumentar y/o estabilizar la funcion cardiaca en pacientes con enfermedad de fabry. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023005628A MX2023005628A (es) | 2017-08-28 | 2020-02-27 | Metodos para aumentar y/o estabilizar la funcion cardiaca en pacientes con enfermedad de fabry. |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20200222377A1 (es) |
| EP (2) | EP4176877A1 (es) |
| JP (2) | JP2020531550A (es) |
| KR (1) | KR20200044908A (es) |
| CN (1) | CN111770753A (es) |
| AR (1) | AR112482A1 (es) |
| AU (1) | AU2018326364A1 (es) |
| BR (1) | BR112020003974A2 (es) |
| CA (1) | CA3074450A1 (es) |
| CL (1) | CL2020000491A1 (es) |
| DK (1) | DK3675853T3 (es) |
| EA (1) | EA202090564A1 (es) |
| ES (1) | ES2931054T3 (es) |
| HR (1) | HRP20221366T1 (es) |
| HU (1) | HUE060287T2 (es) |
| IL (2) | IL310648A (es) |
| LT (1) | LT3675853T (es) |
| MX (2) | MX2020002229A (es) |
| PL (1) | PL3675853T3 (es) |
| PT (1) | PT3675853T (es) |
| RS (1) | RS63742B1 (es) |
| SG (1) | SG11202001707PA (es) |
| TW (1) | TW201919619A (es) |
| WO (1) | WO2019046244A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2652553C (en) | 2006-05-16 | 2020-08-18 | Amicus Therapeutics, Inc. | Use of 1-deoxygalactonojirimycin or a salt thereof in the treatment of fabry disease |
| ES2541933T3 (es) | 2008-02-12 | 2015-07-28 | Amicus Therapeutics, Inc. | Método para predecir la respuesta al tratamiento farmacológico con chaperona de enfermedades |
| US10251873B2 (en) | 2017-05-30 | 2019-04-09 | Amicus Therapeutics, Inc. | Methods of treating fabry patients having renal impairment |
| KR20200128676A (ko) | 2018-02-06 | 2020-11-16 | 아미쿠스 세라퓨틱스, 인코포레이티드 | 임신 환자의 파브리병 치료를 위한 미갈라스타트의 용도 |
| AU2020327019A1 (en) | 2019-08-07 | 2022-03-03 | Amicus Therapeutics, Inc. | Methods of treating Fabry disease in patients having a mutation in the GLA gene |
| US11623916B2 (en) | 2020-12-16 | 2023-04-11 | Amicus Therapeutics, Inc. | Highly purified batches of pharmaceutical grade migalastat and methods of producing the same |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6274597B1 (en) | 1998-06-01 | 2001-08-14 | Mount Sinai School Of Medicine Of New York University | Method of enhancing lysosomal α-Galactosidase A |
| US20100113517A1 (en) | 2007-03-30 | 2010-05-06 | Amicus Therapeutics, Inc. | Method for the treatment of fabry disease using pharmacological chaperones |
| US9999618B2 (en) * | 2007-04-26 | 2018-06-19 | Amicus Therapeutics, Inc. | Dosing regimens for the treatment of lysosomal storage diseases using pharmacological chaperones |
| ES2541933T3 (es) | 2008-02-12 | 2015-07-28 | Amicus Therapeutics, Inc. | Método para predecir la respuesta al tratamiento farmacológico con chaperona de enfermedades |
-
2018
- 2018-08-28 HU HUE18766482A patent/HUE060287T2/hu unknown
- 2018-08-28 US US16/642,620 patent/US20200222377A1/en active Pending
- 2018-08-28 EP EP22194251.9A patent/EP4176877A1/en active Pending
- 2018-08-28 EA EA202090564A patent/EA202090564A1/ru unknown
- 2018-08-28 SG SG11202001707PA patent/SG11202001707PA/en unknown
- 2018-08-28 CN CN201880056413.8A patent/CN111770753A/zh active Pending
- 2018-08-28 CA CA3074450A patent/CA3074450A1/en active Pending
- 2018-08-28 TW TW107129901A patent/TW201919619A/zh unknown
- 2018-08-28 DK DK18766482.6T patent/DK3675853T3/da active
- 2018-08-28 IL IL310648A patent/IL310648A/en unknown
- 2018-08-28 PL PL18766482.6T patent/PL3675853T3/pl unknown
- 2018-08-28 LT LTEPPCT/US2018/048257T patent/LT3675853T/lt unknown
- 2018-08-28 RS RS20221061A patent/RS63742B1/sr unknown
- 2018-08-28 AR ARP180102438 patent/AR112482A1/es unknown
- 2018-08-28 AU AU2018326364A patent/AU2018326364A1/en active Pending
- 2018-08-28 MX MX2020002229A patent/MX2020002229A/es unknown
- 2018-08-28 JP JP2020511971A patent/JP2020531550A/ja active Pending
- 2018-08-28 WO PCT/US2018/048257 patent/WO2019046244A1/en unknown
- 2018-08-28 ES ES18766482T patent/ES2931054T3/es active Active
- 2018-08-28 HR HRP20221366TT patent/HRP20221366T1/hr unknown
- 2018-08-28 PT PT187664826T patent/PT3675853T/pt unknown
- 2018-08-28 EP EP18766482.6A patent/EP3675853B1/en active Active
- 2018-08-28 BR BR112020003974-8A patent/BR112020003974A2/pt unknown
- 2018-08-28 KR KR1020207008736A patent/KR20200044908A/ko not_active Application Discontinuation
- 2018-08-28 IL IL272893A patent/IL272893B1/en unknown
-
2020
- 2020-02-27 MX MX2023005628A patent/MX2023005628A/es unknown
- 2020-02-28 CL CL2020000491A patent/CL2020000491A1/es unknown
-
2022
- 2022-12-20 JP JP2022203783A patent/JP2023051998A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EA202090564A1 (ru) | 2020-06-15 |
| JP2020531550A (ja) | 2020-11-05 |
| CN111770753A (zh) | 2020-10-13 |
| EP3675853A1 (en) | 2020-07-08 |
| US20200222377A1 (en) | 2020-07-16 |
| MX2023005628A (es) | 2023-05-24 |
| AU2018326364A1 (en) | 2020-04-09 |
| DK3675853T3 (da) | 2022-11-28 |
| ES2931054T3 (es) | 2022-12-23 |
| EP4176877A1 (en) | 2023-05-10 |
| KR20200044908A (ko) | 2020-04-29 |
| LT3675853T (lt) | 2022-12-12 |
| PT3675853T (pt) | 2022-11-28 |
| TW201919619A (zh) | 2019-06-01 |
| CL2020000491A1 (es) | 2020-09-11 |
| AR112482A1 (es) | 2019-10-30 |
| EP3675853B1 (en) | 2022-09-07 |
| RS63742B1 (sr) | 2022-12-30 |
| HUE060287T2 (hu) | 2023-02-28 |
| IL272893B1 (en) | 2024-03-01 |
| HRP20221366T1 (hr) | 2023-01-06 |
| SG11202001707PA (en) | 2020-03-30 |
| IL272893A (en) | 2020-04-30 |
| IL310648A (en) | 2024-04-01 |
| JP2023051998A (ja) | 2023-04-11 |
| PL3675853T3 (pl) | 2022-12-27 |
| CA3074450A1 (en) | 2019-03-07 |
| WO2019046244A1 (en) | 2019-03-07 |
| BR112020003974A2 (pt) | 2020-09-01 |
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