MX2019007239A - Nueva formulacion que comprende un derivado de bencimidazol. - Google Patents
Nueva formulacion que comprende un derivado de bencimidazol.Info
- Publication number
- MX2019007239A MX2019007239A MX2019007239A MX2019007239A MX2019007239A MX 2019007239 A MX2019007239 A MX 2019007239A MX 2019007239 A MX2019007239 A MX 2019007239A MX 2019007239 A MX2019007239 A MX 2019007239A MX 2019007239 A MX2019007239 A MX 2019007239A
- Authority
- MX
- Mexico
- Prior art keywords
- benzimidazole derivative
- preparation containing
- preparation
- novel preparation
- oral administration
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 4
- 125000003785 benzimidazolyl group Chemical class N1=C(NC2=C1C=CC=C2)* 0.000 title abstract 2
- 229920002785 Croscarmellose sodium Polymers 0.000 abstract 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 abstract 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229960001681 croscarmellose sodium Drugs 0.000 abstract 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 abstract 1
- 230000006866 deterioration Effects 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 abstract 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940079832 sodium starch glycolate Drugs 0.000 abstract 1
- 229920003109 sodium starch glycolate Polymers 0.000 abstract 1
- 239000008109 sodium starch glycolate Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2063—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
Abstract
La presente invención se refiere a una nueva formulación que comprende un derivado de bencimidazol. La formulación para administración oral que comprende un compuesto de Fórmula 1 de acuerdo con la presente invención o una sal farmacéuticamente aceptable del mismo; y al menos un disgregante seleccionado del grupo que consiste en croscarmelosa de sodio, almidón glicolato sódico ye hidroxipropilcelulosa con bajo grado de sustitución, muestra una excelente estabilidad durante el almacenamiento y tiene un efecto en la prevención de un fenómeno de disminución en la velocidad de disolución, usándose de esta manera de forma útil como una formulación para administración oral.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020160179334A KR101960357B1 (ko) | 2016-12-26 | 2016-12-26 | 벤즈이미다졸 유도체를 포함하는 신규한 제제 |
| PCT/KR2017/015489 WO2018124700A1 (ko) | 2016-12-26 | 2017-12-26 | 벤즈이미다졸 유도체를 포함하는 신규한 제제 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019007239A true MX2019007239A (es) | 2019-08-16 |
Family
ID=62710016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019007239A MX2019007239A (es) | 2016-12-26 | 2017-12-26 | Nueva formulacion que comprende un derivado de bencimidazol. |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US11576898B2 (es) |
| EP (1) | EP3560482B9 (es) |
| JP (1) | JP6814886B2 (es) |
| KR (1) | KR101960357B1 (es) |
| CN (2) | CN110121333B (es) |
| AR (1) | AR110453A1 (es) |
| BR (1) | BR112019013098A2 (es) |
| ES (1) | ES2887020T3 (es) |
| JO (1) | JOP20170197B1 (es) |
| MX (1) | MX2019007239A (es) |
| MY (1) | MY191261A (es) |
| PH (1) | PH12019501288A1 (es) |
| TW (1) | TWI658841B (es) |
| UY (1) | UY37550A (es) |
| WO (1) | WO2018124700A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112021016212A2 (pt) * | 2019-02-18 | 2021-10-05 | Hk Inno.N Corporation | Composição farmacêutica para prevenir a recorrência da doença do refluxo gastroesofágico e uso da dita composição |
| CA3175402A1 (en) * | 2020-04-13 | 2021-10-21 | Seokuee KIM | Pharmaceutical composition comprising benzimidazole derivative compound |
| KR20220054211A (ko) * | 2020-10-23 | 2022-05-02 | 에이치케이이노엔 주식회사 | 벤즈이미다졸 유도체 화합물을 포함하는 구강붕해정 및 이의 제조방법 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0620081B8 (pt) * | 2005-12-19 | 2021-05-25 | Pfizer | composto e composição farmacêutica. |
| JP2009538901A (ja) | 2006-06-01 | 2009-11-12 | デクセル ファーマ テクノロジーズ エルティーディー． | 複式ユニット製薬的製剤 |
| WO2008072535A1 (ja) | 2006-12-07 | 2008-06-19 | Daiichi Sankyo Company, Limited | 低置換度ヒドロキシプロピルセルロースを含有する医薬組成物 |
| KR20160144927A (ko) | 2015-06-08 | 2016-12-19 | 씨제이헬스케어 주식회사 | 야간 산 분비에 대한 벤즈이미다졸 유도체의 용도 |
-
2016
- 2016-12-26 KR KR1020160179334A patent/KR101960357B1/ko active IP Right Grant
-
2017
- 2017-12-26 WO PCT/KR2017/015489 patent/WO2018124700A1/ko unknown
- 2017-12-26 AR ARP170103679A patent/AR110453A1/es unknown
- 2017-12-26 CN CN201780080890.3A patent/CN110121333B/zh active Active
- 2017-12-26 BR BR112019013098A patent/BR112019013098A2/pt active Search and Examination
- 2017-12-26 US US16/473,748 patent/US11576898B2/en active Active
- 2017-12-26 ES ES17888189T patent/ES2887020T3/es active Active
- 2017-12-26 MY MYPI2019003688A patent/MY191261A/en unknown
- 2017-12-26 CN CN202310720657.4A patent/CN116869915A/zh active Pending
- 2017-12-26 TW TW106145654A patent/TWI658841B/zh active
- 2017-12-26 JO JOP/2017/0197A patent/JOP20170197B1/ar active
- 2017-12-26 EP EP17888189.2A patent/EP3560482B9/en active Active
- 2017-12-26 UY UY0001037550A patent/UY37550A/es unknown
- 2017-12-26 JP JP2019533412A patent/JP6814886B2/ja active Active
- 2017-12-26 MX MX2019007239A patent/MX2019007239A/es unknown
-
2019
- 2019-06-07 PH PH12019501288A patent/PH12019501288A1/en unknown
-
2023
- 2023-01-11 US US18/095,971 patent/US20230277506A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| PH12019501288A1 (en) | 2019-12-02 |
| MY191261A (en) | 2022-06-12 |
| JOP20170197A1 (ar) | 2019-01-30 |
| US20230277506A1 (en) | 2023-09-07 |
| US11576898B2 (en) | 2023-02-14 |
| CN110121333B (zh) | 2023-07-04 |
| ES2887020T3 (es) | 2021-12-21 |
| KR20180075235A (ko) | 2018-07-04 |
| JP2020502208A (ja) | 2020-01-23 |
| UY37550A (es) | 2018-07-31 |
| KR101960357B1 (ko) | 2019-03-20 |
| AR110453A1 (es) | 2019-03-27 |
| CN116869915A (zh) | 2023-10-13 |
| TW201828928A (zh) | 2018-08-16 |
| JOP20170197B1 (ar) | 2022-03-14 |
| CN110121333A (zh) | 2019-08-13 |
| EP3560482A1 (en) | 2019-10-30 |
| EP3560482B1 (en) | 2021-08-18 |
| EP3560482B9 (en) | 2022-04-20 |
| TWI658841B (zh) | 2019-05-11 |
| JP6814886B2 (ja) | 2021-01-20 |
| WO2018124700A1 (ko) | 2018-07-05 |
| BR112019013098A2 (pt) | 2019-12-17 |
| US20200392120A1 (en) | 2020-12-17 |
| EP3560482A4 (en) | 2020-08-19 |
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