MX2019004219A - Metodo para la deteccion de la apolipoproteina e4. - Google Patents

Metodo para la deteccion de la apolipoproteina e4.

Info

Publication number
MX2019004219A
MX2019004219A MX2019004219A MX2019004219A MX2019004219A MX 2019004219 A MX2019004219 A MX 2019004219A MX 2019004219 A MX2019004219 A MX 2019004219A MX 2019004219 A MX2019004219 A MX 2019004219A MX 2019004219 A MX2019004219 A MX 2019004219A
Authority
MX
Mexico
Prior art keywords
apoe4
apolipoprotein
detection
binder
sample
Prior art date
Application number
MX2019004219A
Other languages
English (en)
Inventor
Bergmann Andreas
Original Assignee
Sphingotec Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sphingotec Gmbh filed Critical Sphingotec Gmbh
Publication of MX2019004219A publication Critical patent/MX2019004219A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/775—Apolipopeptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La presente invención proporciona un método para la detección de la apolipoproteína E isotipo 4 (ApoE4) o los fragmentos de la misma en una muestra sanguínea de un sujeto, con lo cual el método comprende los pasos de poner en contacto la muestra con una fase sólida, poner en contacto la muestra con al menos una aglutinante que se une específicamente a la ApoE4 o un fragmento de la misma, formando con esto un complejo de ApoE4-aglutinante, y detectando el complejo de ApoE4-aglutinante.
MX2019004219A 2016-10-12 2017-10-12 Metodo para la deteccion de la apolipoproteina e4. MX2019004219A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16193587.9A EP3309550A1 (en) 2016-10-12 2016-10-12 Method for the detection of apolipoprotein e4
PCT/EP2017/076046 WO2018069437A1 (en) 2016-10-12 2017-10-12 Method for the detection of apolipoprotein e4

Publications (1)

Publication Number Publication Date
MX2019004219A true MX2019004219A (es) 2019-06-10

Family

ID=57153320

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019004219A MX2019004219A (es) 2016-10-12 2017-10-12 Metodo para la deteccion de la apolipoproteina e4.

Country Status (9)

Country Link
US (1) US20210223242A1 (es)
EP (2) EP3309550A1 (es)
JP (2) JP2019536007A (es)
CN (1) CN109891240B (es)
AU (1) AU2017342043A1 (es)
BR (1) BR112019007096A2 (es)
CA (1) CA3039756A1 (es)
MX (1) MX2019004219A (es)
WO (1) WO2018069437A1 (es)

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CN114174330A (zh) * 2019-05-28 2022-03-11 总医院公司 Apoe抗体、融合蛋白及其用途
CN112540179B (zh) * 2020-08-06 2023-07-07 武汉天德生物科技有限公司 一种测试ApoE4蛋白含量的ELISA试剂盒
EP4230736A1 (en) 2020-10-14 2023-08-23 Shimadzu Corporation Method for detecting genetic polymorphism
CN113419059B (zh) * 2021-06-30 2023-09-01 迈克生物股份有限公司 用于化学发光免疫分析方法的封闭剂

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Also Published As

Publication number Publication date
BR112019007096A2 (pt) 2019-06-25
CN109891240A (zh) 2019-06-14
JP2023002599A (ja) 2023-01-10
RU2019113771A (ru) 2020-11-13
EP3526605A1 (en) 2019-08-21
US20210223242A1 (en) 2021-07-22
CN109891240B (zh) 2023-06-30
WO2018069437A1 (en) 2018-04-19
AU2017342043A8 (en) 2019-05-02
CA3039756A1 (en) 2018-04-19
AU2017342043A1 (en) 2019-04-11
JP2019536007A (ja) 2019-12-12
RU2019113771A3 (es) 2021-02-04
EP3309550A1 (en) 2018-04-18

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