MX2019001596A - Uso y dosificacion de agentes terapeuticos para endometriosis. - Google Patents
Uso y dosificacion de agentes terapeuticos para endometriosis.Info
- Publication number
- MX2019001596A MX2019001596A MX2019001596A MX2019001596A MX2019001596A MX 2019001596 A MX2019001596 A MX 2019001596A MX 2019001596 A MX2019001596 A MX 2019001596A MX 2019001596 A MX2019001596 A MX 2019001596A MX 2019001596 A MX2019001596 A MX 2019001596A
- Authority
- MX
- Mexico
- Prior art keywords
- endometriosis
- dosage
- administration
- pharmaceutical composition
- therapeutic agent
- Prior art date
Links
- 201000009273 Endometriosis Diseases 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 2
- 229940124597 therapeutic agent Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a agentes farmacéuticos que reducen el riesgo de disminuir la densidad mineral ósea a causa de su efecto reductor de los niveles de estrógeno, y ejercen excelentes efectos terapéuticos sobre la endometriosis. La presente invención se refiere a composiciones farmacéuticas para el tratamiento de la endometriosis, que comprenden el ácido 3-[2-fluoro-5-(2,3-difluoro-6-metoxibenciloxi)-4-metoxifenil]-2,4 -dioxo-1,2,3,4-tetrahidrotieno-[3,4-d]-pirimidin-5-carboxílico o una sal farmacéuticamente aceptable del mismo, los cuales se administran por vía oral una vez al día, a una dosis diaria de entre 50 mg y 75 mg, calculada en forma de base libre.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016155175 | 2016-08-08 | ||
| PCT/JP2017/028504 WO2018030317A1 (ja) | 2016-08-08 | 2017-08-07 | 子宮内膜症治療剤の用法・用量 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019001596A true MX2019001596A (es) | 2019-09-19 |
Family
ID=61162249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019001596A MX2019001596A (es) | 2016-08-08 | 2017-08-07 | Uso y dosificacion de agentes terapeuticos para endometriosis. |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US10646491B2 (es) |
| EP (1) | EP3498280B1 (es) |
| JP (1) | JP6987060B2 (es) |
| KR (1) | KR102433001B1 (es) |
| CN (2) | CN116270656A (es) |
| AU (1) | AU2017309015B2 (es) |
| BR (1) | BR112019002513A2 (es) |
| CA (1) | CA3025760A1 (es) |
| EA (1) | EA039240B1 (es) |
| IL (2) | IL292027A (es) |
| MX (1) | MX2019001596A (es) |
| TW (1) | TWI746613B (es) |
| UA (1) | UA123114C2 (es) |
| WO (1) | WO2018030317A1 (es) |
| ZA (1) | ZA201900777B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110996956A (zh) | 2017-06-05 | 2020-04-10 | 奥布赛瓦股份公司 | 用于治疗子宫内膜异位症的促性腺激素释放激素拮抗剂给药方案 |
| AU2018280741B2 (en) | 2017-06-05 | 2023-12-21 | Kissei Pharmaceutical Co., Ltd. | Gonadotropin-releasing hormone antagonist dosing regimens for treating uterine fibroids and reducing menstrual blood loss |
| CA3117092A1 (en) * | 2018-10-29 | 2020-05-07 | ObsEva S.A. | Compositions and methods for the treatment of adenomyosis and rectovaginal endometriosis |
| JP7459086B2 (ja) | 2018-11-07 | 2024-04-01 | キッセイ薬品工業株式会社 | エストロゲン依存性障害の治療のための組成物及び方法 |
| CN115232144B (zh) * | 2021-04-22 | 2024-04-02 | 长春金赛药业有限责任公司 | 含氮稠环类衍生物、药物组合物及其制备方法和应用 |
| TW202342054A (zh) * | 2022-02-04 | 2023-11-01 | 日商橘生藥品工業股份有限公司 | 經口固形製劑 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1939204E (pt) | 2005-10-19 | 2013-03-14 | Kissei Pharmaceutical | Derivado heterocíclico fundido, composição medicinal contendo o mesmo, e sua utilização medicinal |
| US9169266B2 (en) * | 2010-02-10 | 2015-10-27 | Kissei Pharmaceutical Co., Ltd. | Salt of fused heterocyclic derivative and crystal thereof |
-
2017
- 2017-08-07 MX MX2019001596A patent/MX2019001596A/es unknown
- 2017-08-07 KR KR1020197000066A patent/KR102433001B1/ko active IP Right Grant
- 2017-08-07 IL IL292027A patent/IL292027A/en unknown
- 2017-08-07 EA EA201990249A patent/EA039240B1/ru unknown
- 2017-08-07 TW TW106126582A patent/TWI746613B/zh active
- 2017-08-07 EP EP17839388.0A patent/EP3498280B1/en active Active
- 2017-08-07 CA CA3025760A patent/CA3025760A1/en active Pending
- 2017-08-07 AU AU2017309015A patent/AU2017309015B2/en active Active
- 2017-08-07 CN CN202310437343.3A patent/CN116270656A/zh active Pending
- 2017-08-07 US US16/322,227 patent/US10646491B2/en active Active
- 2017-08-07 CN CN201780043097.6A patent/CN109562112A/zh active Pending
- 2017-08-07 JP JP2018533017A patent/JP6987060B2/ja active Active
- 2017-08-07 WO PCT/JP2017/028504 patent/WO2018030317A1/ja unknown
- 2017-08-07 BR BR112019002513-8A patent/BR112019002513A2/pt unknown
- 2017-08-07 UA UAA201901236A patent/UA123114C2/uk unknown
-
2019
- 2019-01-30 IL IL264554A patent/IL264554B/en unknown
- 2019-02-06 ZA ZA2019/00777A patent/ZA201900777B/en unknown
-
2020
- 2020-04-08 US US16/843,260 patent/US11382914B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN109562112A (zh) | 2019-04-02 |
| US11382914B2 (en) | 2022-07-12 |
| CN116270656A (zh) | 2023-06-23 |
| EA201990249A1 (ru) | 2019-07-31 |
| AU2017309015B2 (en) | 2022-09-15 |
| CA3025760A1 (en) | 2018-02-15 |
| BR112019002513A2 (pt) | 2019-05-14 |
| US20210046078A1 (en) | 2021-02-18 |
| IL292027A (en) | 2022-06-01 |
| US10646491B2 (en) | 2020-05-12 |
| EA039240B1 (ru) | 2021-12-22 |
| UA123114C2 (uk) | 2021-02-17 |
| IL264554A (en) | 2019-02-28 |
| WO2018030317A1 (ja) | 2018-02-15 |
| JP6987060B2 (ja) | 2021-12-22 |
| US20190175600A1 (en) | 2019-06-13 |
| ZA201900777B (en) | 2020-08-26 |
| JPWO2018030317A1 (ja) | 2019-06-13 |
| KR102433001B1 (ko) | 2022-08-18 |
| TWI746613B (zh) | 2021-11-21 |
| EP3498280A4 (en) | 2020-03-18 |
| EP3498280B1 (en) | 2024-04-03 |
| EP3498280A1 (en) | 2019-06-19 |
| AU2017309015A1 (en) | 2019-02-14 |
| KR20190037225A (ko) | 2019-04-05 |
| TW201808297A (zh) | 2018-03-16 |
| IL264554B (en) | 2022-05-01 |
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