MX2018015119A - Particulas de nicotina. - Google Patents

Particulas de nicotina.

Info

Publication number
MX2018015119A
MX2018015119A MX2018015119A MX2018015119A MX2018015119A MX 2018015119 A MX2018015119 A MX 2018015119A MX 2018015119 A MX2018015119 A MX 2018015119A MX 2018015119 A MX2018015119 A MX 2018015119A MX 2018015119 A MX2018015119 A MX 2018015119A
Authority
MX
Mexico
Prior art keywords
particles
nicotine particles
liquid mixture
nicotine
liquid
Prior art date
Application number
MX2018015119A
Other languages
English (en)
Inventor
VOLPE Nicolo
Original Assignee
Philip Morris Products Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philip Morris Products Sa filed Critical Philip Morris Products Sa
Publication of MX2018015119A publication Critical patent/MX2018015119A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465Nicotine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Addiction (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Manufacture Of Tobacco Products (AREA)

Abstract

Un método incluye combinar nicotina con un líquido portador para formar una mezcla líquida y secar por atomizado la mezcla líquida para formar una primera pluralidad de partículas. La primera pluralidad de partículas se mueles para formar una segunda pluralidad de partículas.
MX2018015119A 2016-06-30 2017-06-21 Particulas de nicotina. MX2018015119A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16177156 2016-06-30
PCT/IB2017/053710 WO2018002779A1 (en) 2016-06-30 2017-06-21 Nicotine particles

Publications (1)

Publication Number Publication Date
MX2018015119A true MX2018015119A (es) 2019-04-15

Family

ID=56296658

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018015119A MX2018015119A (es) 2016-06-30 2017-06-21 Particulas de nicotina.

Country Status (16)

Country Link
US (2) US11458093B2 (es)
EP (1) EP3478265A1 (es)
JP (2) JP7471774B2 (es)
KR (1) KR102559152B1 (es)
CN (1) CN109310623B (es)
AU (1) AU2017290610A1 (es)
BR (1) BR112018075017A2 (es)
CA (1) CA3023626A1 (es)
IL (1) IL263340A (es)
MX (1) MX2018015119A (es)
PH (1) PH12018502715A1 (es)
RU (1) RU2741309C2 (es)
SG (1) SG11201809630RA (es)
UA (1) UA126853C2 (es)
WO (1) WO2018002779A1 (es)
ZA (1) ZA201807080B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190133940A1 (en) * 2016-06-30 2019-05-09 Philip Morris Products S.A. Nicotine particles and compositions
CA3048677A1 (en) * 2017-03-07 2018-09-13 Philip Morris Products S.A. Inhalable nicotine formulations, and methods of making and using thereof
ES2965397T3 (es) 2019-11-14 2024-04-15 Philip Morris Products Sa Formulación mejorada de polvo seco con sabor a tabaco
KR20230024889A (ko) * 2020-06-15 2023-02-21 필립모리스 프로덕츠 에스.에이. 아나타빈 분말 조성물
MX2023002467A (es) * 2020-09-03 2023-03-23 Philip Morris Products Sa Composiciones en polvo activas de baja higroscopicidad secadas por atomizado.
US20220313678A1 (en) * 2021-04-06 2022-10-06 Altria Client Services Llc Spray dried nicotine for inclusion in oral products
WO2024090892A1 (ko) * 2022-10-27 2024-05-02 주식회사 케이티앤지 흡입용 니코틴 건조 분말의 제조 방법
WO2024090890A1 (ko) * 2022-10-27 2024-05-02 주식회사 케이티앤지 흡입용 저용량 니코틴 건조 분말 조성물

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4655231A (en) 1984-01-09 1987-04-07 Advanced Tobacco Products, Inc. Snuff and preparation thereof
JP3388896B2 (ja) * 1994-08-08 2003-03-24 株式会社日立ユニシアオートモティブ 吸入式投薬器
GB9515182D0 (en) 1995-07-24 1995-09-20 Co Ordinated Drug Dev Improvements in and relating to powders for use in dry powder inhalers
CA2231968A1 (en) 1998-03-11 1999-09-11 Smoke-Stop, A Partnership Consisting Of Art Slutsky Method of producing a nicotine medicament
US20120042886A1 (en) 1998-03-11 2012-02-23 Hanna Piskorz Method of producing a nicotine medicament and a medicament made by the method
US6799576B2 (en) 1999-07-16 2004-10-05 Aradigm Corporation System for effecting smoking cessation
US8256433B2 (en) 1999-07-16 2012-09-04 Aradigm Corporation Systems and methods for effecting cessation of tobacco use
US20080138398A1 (en) 1999-07-16 2008-06-12 Aradigm Corporation Dual release nicotine formulations, and systems and methods for their use
US6586008B1 (en) * 1999-08-25 2003-07-01 Advanced Inhalation Research, Inc. Use of simple amino acids to form porous particles during spray drying
US6962006B2 (en) * 2002-12-19 2005-11-08 Acusphere, Inc. Methods and apparatus for making particles using spray dryer and in-line jet mill
GB0425758D0 (en) 2004-11-23 2004-12-22 Vectura Ltd Preparation of pharmaceutical compositions
ITMI20051999A1 (it) * 2005-10-21 2007-04-22 Eratech S R L Formulazioni inalatorie di farmaci in fora di polvere secca per somministrazione come tale o con nebulizzatore e dotate di elevata erogabilita' respirabilita' e stabilita'
FI20060428L (fi) 2006-05-03 2007-11-04 Esko Kauppinen Pintamodifioidut aerosolihiukkaset, menetelmä ja laite niiden tuottamiseksi sekä jauheet ja dispersiot jotka sisältävät kyseisiä hiukkasia
JP2012509922A (ja) 2008-11-27 2012-04-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規粉末化結晶質吸入薬
PL3111926T3 (pl) 2009-05-29 2020-06-29 Pearl Therapeutics, Inc. Kompozycje, sposoby i układy do dostarczania dwóch lub większej liczby środków czynnych do układu oddechowego
WO2013130767A1 (en) 2012-02-29 2013-09-06 Pulmatrix, Inc. Inhalable dry powders
SE536491C2 (sv) 2012-03-26 2013-12-27 Bionicotine Ab Påse innehållande nikotin och en tuggummikomposition
US20140261474A1 (en) 2013-03-15 2014-09-18 Aradigm Corporation Methods for inhalation of smoke-free nicotine
ITMI20130572A1 (it) 2013-04-10 2014-10-11 Eratech Srl Composizione comprendente almeno due polveri secche ottenute per spray dry per aumentare la stabilita' della formulazione
CN117137195A (zh) 2013-05-06 2023-12-01 尤尔实验室有限公司 用于气溶胶装置的烟碱盐调配物及其方法
CA2944471C (en) 2014-04-08 2020-03-31 Sansa Corporation (Barbados) Inc. Nicotine formulations and methods of making the same
KR102428028B1 (ko) * 2014-04-28 2022-08-03 필립모리스 프로덕츠 에스.에이. 향미를 가진 니코틴 분말 흡입기

Also Published As

Publication number Publication date
US20190117567A1 (en) 2019-04-25
RU2018144108A (ru) 2020-07-30
KR102559152B1 (ko) 2023-07-26
RU2018144108A3 (es) 2020-07-30
UA126853C2 (uk) 2023-02-15
KR20190026655A (ko) 2019-03-13
WO2018002779A1 (en) 2018-01-04
JP7471774B2 (ja) 2024-04-22
RU2741309C2 (ru) 2021-01-25
BR112018075017A2 (pt) 2019-03-19
US20230000767A1 (en) 2023-01-05
ZA201807080B (en) 2019-07-31
IL263340A (en) 2018-12-31
CN109310623A (zh) 2019-02-05
JP2022116082A (ja) 2022-08-09
CA3023626A1 (en) 2018-01-04
EP3478265A1 (en) 2019-05-08
AU2017290610A1 (en) 2018-11-15
JP2019519542A (ja) 2019-07-11
PH12018502715A1 (en) 2019-07-29
US11458093B2 (en) 2022-10-04
CN109310623B (zh) 2022-10-21
SG11201809630RA (en) 2018-11-29

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