MX2018011170A - Metodos y composiciones para incrementar la produccion de arn bicatenario. - Google Patents
Metodos y composiciones para incrementar la produccion de arn bicatenario.Info
- Publication number
- MX2018011170A MX2018011170A MX2018011170A MX2018011170A MX2018011170A MX 2018011170 A MX2018011170 A MX 2018011170A MX 2018011170 A MX2018011170 A MX 2018011170A MX 2018011170 A MX2018011170 A MX 2018011170A MX 2018011170 A MX2018011170 A MX 2018011170A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- compositions
- double stranded
- stranded rna
- dsrna
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2330/00—Production
- C12N2330/50—Biochemical production, i.e. in a transformed host cell
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/18011—Details ssRNA Bacteriophages positive-sense
- C12N2795/18111—Leviviridae
- C12N2795/18122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se presentan métodos y materiales para la producción in vivo mejorada del ARNds. Los rendimientos del ARNds aumentan significativamente en presencia de la proteína de la cápside. El rendimiento mejorado del ARNds no depende de la presencia de sitios de unión afines específicos para la proteína de la cápside asociada con el ARNds, sino que depende de la proteína de la cápside.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662308381P | 2016-03-15 | 2016-03-15 | |
PCT/US2017/021661 WO2017160600A1 (en) | 2016-03-15 | 2017-03-09 | Methods and compositions for increased double stranded rna production |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018011170A true MX2018011170A (es) | 2019-05-16 |
Family
ID=59851196
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018011170A MX2018011170A (es) | 2016-03-15 | 2017-03-09 | Metodos y composiciones para incrementar la produccion de arn bicatenario. |
MX2020013746A MX2020013746A (es) | 2016-03-15 | 2018-09-14 | Metodos y composiciones para incrementar la produccion de arn bicatenario. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020013746A MX2020013746A (es) | 2016-03-15 | 2018-09-14 | Metodos y composiciones para incrementar la produccion de arn bicatenario. |
Country Status (11)
Country | Link |
---|---|
US (3) | US10704045B2 (es) |
EP (1) | EP3429336A4 (es) |
JP (2) | JP7140386B2 (es) |
CN (2) | CN109196102B (es) |
AU (1) | AU2017233862B2 (es) |
BR (1) | BR112018068144A2 (es) |
CA (1) | CA3016899C (es) |
IL (1) | IL261516A (es) |
MX (2) | MX2018011170A (es) |
SG (1) | SG11201807478QA (es) |
WO (1) | WO2017160600A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016183022A1 (en) * | 2015-05-12 | 2016-11-17 | Apse, Llc | In vivo production of long double stranded rna utilizing vlps |
SG11201807478QA (en) | 2016-03-15 | 2018-09-27 | Apse Inc | Methods and compositions for increased double stranded rna production |
CN110494567B (zh) * | 2017-03-28 | 2024-07-12 | 味之素株式会社 | 生产rna的方法 |
EP3976787A4 (en) * | 2019-05-30 | 2023-10-25 | Rnaissance AG L.L.C | METHODS AND COMPOSITIONS FOR MICROBIAL ADMINISTRATION OF DOUBLE STRANDED RNA |
WO2020243593A1 (en) | 2019-05-30 | 2020-12-03 | Apse, Inc. | Improved methods and compositions for increased double stranded rna production |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020164585A1 (en) | 1998-01-16 | 2002-11-07 | Sean Chapman | Method for enhancing RNA or protein production using non-native 5' untranslated sequences in recombinant viral nucleic acids |
US8772254B2 (en) | 2004-10-25 | 2014-07-08 | Devgen N.V. | Method and constructs for delivering double stranded RNA to pest organisms |
CA2608579C (en) * | 2005-05-26 | 2019-09-10 | Cytos Biotechnology Ag | Scalable fermentation process |
US8324149B2 (en) * | 2008-11-18 | 2012-12-04 | The Board Of Trustees Of The Leland Stanford Junior University | Encapsidation of heterologous entities into virus-like particles |
JP6041896B2 (ja) | 2011-12-21 | 2016-12-14 | アプス, エルエルシー | 加水分解酵素に対して耐性があるカプシドを有するvlpを用いるプロセス |
GB201202119D0 (en) | 2012-02-08 | 2012-03-21 | Univ Swansea | Pest and pathogen control |
KR102271292B1 (ko) * | 2013-03-15 | 2021-07-02 | 더 제너럴 하스피탈 코포레이션 | Rna-안내 게놈 편집의 특이성을 증가시키기 위한 rna-안내 foki 뉴클레아제(rfn)의 용도 |
ES2691803T3 (es) | 2013-03-15 | 2018-11-28 | Monsanto Technology Llc | Composiciones y procedimientos para la producción y administración de ARN |
MX364809B (es) | 2013-06-19 | 2019-05-07 | Apse Llc | Composiciones y metodos que se usan capsides resistentes a hidrolasas. |
WO2015038746A1 (en) * | 2013-09-11 | 2015-03-19 | Georgia Tech Research Corporation | Compositions and methods for inhibiting gene expression |
US10329560B2 (en) | 2013-09-23 | 2019-06-25 | Georgia Tech Research Corporation | Targeting non-coding RNA for RNA interference |
WO2015073720A1 (en) | 2013-11-14 | 2015-05-21 | Scarab Genomics, Llc | Bacteria with improved metabolic capacity |
WO2016183022A1 (en) | 2015-05-12 | 2016-11-17 | Apse, Llc | In vivo production of long double stranded rna utilizing vlps |
SG11201807478QA (en) | 2016-03-15 | 2018-09-27 | Apse Inc | Methods and compositions for increased double stranded rna production |
-
2017
- 2017-03-09 SG SG11201807478QA patent/SG11201807478QA/en unknown
- 2017-03-09 BR BR112018068144A patent/BR112018068144A2/pt not_active Application Discontinuation
- 2017-03-09 CN CN201780018422.3A patent/CN109196102B/zh active Active
- 2017-03-09 US US16/084,545 patent/US10704045B2/en active Active
- 2017-03-09 JP JP2018548933A patent/JP7140386B2/ja active Active
- 2017-03-09 CA CA3016899A patent/CA3016899C/en active Active
- 2017-03-09 WO PCT/US2017/021661 patent/WO2017160600A1/en active Application Filing
- 2017-03-09 MX MX2018011170A patent/MX2018011170A/es unknown
- 2017-03-09 CN CN202210337486.2A patent/CN115927299A/zh active Pending
- 2017-03-09 AU AU2017233862A patent/AU2017233862B2/en active Active
- 2017-03-09 EP EP17767194.8A patent/EP3429336A4/en active Pending
-
2018
- 2018-09-02 IL IL261516A patent/IL261516A/en unknown
- 2018-09-14 MX MX2020013746A patent/MX2020013746A/es unknown
-
2020
- 2020-07-07 US US16/922,948 patent/US11718851B2/en active Active
-
2022
- 2022-04-15 JP JP2022067530A patent/JP7544761B2/ja active Active
-
2023
- 2023-06-27 US US18/342,407 patent/US20230416744A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2017233862B2 (en) | 2023-04-13 |
WO2017160600A1 (en) | 2017-09-21 |
SG11201807478QA (en) | 2018-09-27 |
CN109196102A (zh) | 2019-01-11 |
AU2017233862A1 (en) | 2018-10-04 |
CA3016899C (en) | 2023-09-19 |
CA3016899A1 (en) | 2017-09-21 |
US20190093108A1 (en) | 2019-03-28 |
IL261516A (en) | 2018-10-31 |
JP2019508060A (ja) | 2019-03-28 |
US20230416744A1 (en) | 2023-12-28 |
JP7544761B2 (ja) | 2024-09-03 |
CN109196102B (zh) | 2022-04-26 |
EP3429336A1 (en) | 2019-01-23 |
US11718851B2 (en) | 2023-08-08 |
US20220145294A1 (en) | 2022-05-12 |
US10704045B2 (en) | 2020-07-07 |
BR112018068144A2 (pt) | 2019-02-12 |
CN115927299A (zh) | 2023-04-07 |
JP2022087312A (ja) | 2022-06-09 |
JP7140386B2 (ja) | 2022-09-21 |
MX2020013746A (es) | 2021-03-02 |
EP3429336A4 (en) | 2019-10-30 |
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