MX2018005313A - Vesiculas extracelulares de las celulas neurales. - Google Patents
Vesiculas extracelulares de las celulas neurales.Info
- Publication number
- MX2018005313A MX2018005313A MX2018005313A MX2018005313A MX2018005313A MX 2018005313 A MX2018005313 A MX 2018005313A MX 2018005313 A MX2018005313 A MX 2018005313A MX 2018005313 A MX2018005313 A MX 2018005313A MX 2018005313 A MX2018005313 A MX 2018005313A
- Authority
- MX
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- Prior art keywords
- vessicles
- neural cell
- cell extracellular
- evs
- extracellular
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
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- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
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- A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5176—Compounds of unknown constitution, e.g. material from plants or animals
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
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- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Neurosurgery (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Botany (AREA)
- Physics & Mathematics (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Molecular Biology (AREA)
Abstract
Se describen en el presente documento vesículas extracelulares (EV) neurales y métodos para utilizar estas EV en el tratamiento de lesión de la médula espinal, accidente cerebrovascular y lesión traumática del cerebro y enfermedades neurodegenerativas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562256823P | 2015-11-18 | 2015-11-18 | |
PCT/US2016/062245 WO2017087500A1 (en) | 2015-11-18 | 2016-11-16 | Neural cell extracellular vessicles |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018005313A true MX2018005313A (es) | 2018-09-05 |
Family
ID=58717775
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018005313A MX2018005313A (es) | 2015-11-18 | 2016-11-16 | Vesiculas extracelulares de las celulas neurales. |
Country Status (15)
Country | Link |
---|---|
US (3) | US11993787B2 (es) |
EP (1) | EP3377078A4 (es) |
JP (2) | JP7075594B2 (es) |
KR (1) | KR20180086440A (es) |
CN (1) | CN108697740A (es) |
AU (1) | AU2016357303B2 (es) |
BR (1) | BR112018009891A2 (es) |
CA (1) | CA3004450A1 (es) |
EA (1) | EA201891152A1 (es) |
HK (1) | HK1256911A1 (es) |
IL (1) | IL259470B (es) |
MX (1) | MX2018005313A (es) |
NZ (1) | NZ742327A (es) |
SG (1) | SG11201804117XA (es) |
WO (1) | WO2017087500A1 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP7075594B2 (ja) | 2015-11-18 | 2022-05-26 | ユニバーシティ オブ ジョージア リサーチ ファウンデーション, インコーポレーテッド | 神経細胞の細胞外小胞 |
US11073511B2 (en) * | 2016-02-01 | 2021-07-27 | The Board Of Trustees Of The Leland Stanford Junior University | Exosome-Total-Isolation-Chip (ExoTIC) device for isolation of exosome-based biomarkers |
CN111699391A (zh) | 2017-12-29 | 2020-09-22 | 雅培实验室 | 用于诊断和评估创伤性脑损伤的新型生物标志物和方法 |
CN110317788A (zh) * | 2019-04-26 | 2019-10-11 | 广州瑞臻再生医学科技有限公司 | 一种npc培养基、外泌体的制备方法和应用 |
CN117384828A (zh) * | 2019-06-10 | 2024-01-12 | 布瑞克斯奥根株式会社 | 用于促进干细胞来源外泌体产生和增加干性的包含透明质酸的组合物 |
JP2022549328A (ja) * | 2019-09-25 | 2022-11-24 | コディアック バイオサイエンシーズ, インコーポレイテッド | 細胞外小胞組成物 |
EP4054631A1 (en) * | 2019-11-04 | 2022-09-14 | Aruna Biomedical, Inc. | Extracellular vesicles and uses thereof for antibody delivery |
KR102630220B1 (ko) * | 2019-11-12 | 2024-01-29 | 브렉소젠 주식회사 | 유도만능줄기세포-유래 중간엽 줄기세포 전구세포로부터 유래된 엑소좀을 포함하는 신장 질환의 예방 또는 치료용 조성물 |
WO2021184020A1 (en) * | 2020-03-13 | 2021-09-16 | Codiak Biosciences, Inc. | Methods of treating neuroinflammation |
WO2021198954A1 (en) * | 2020-03-31 | 2021-10-07 | Universidade Do Minho | Exosome-enriched extracellualr vesicles isolation, method and uses thereof |
CN113577108B (zh) * | 2021-08-31 | 2023-07-07 | 中国科学院苏州纳米技术与纳米仿生研究所 | 一种多功能胶原支架、其制备方法与应用 |
CN113887569B (zh) * | 2021-09-09 | 2022-10-25 | 同济大学 | 一种基于区域尺度的事故多发区域判别方法 |
WO2023055222A1 (ko) * | 2021-10-01 | 2023-04-06 | 주식회사 입셀 | 유도만능줄기세포 배양 배지 유래 성분을 포함하는 조성물 내지 이의 용도 |
WO2023056606A1 (en) * | 2021-10-08 | 2023-04-13 | Hangzhou Jijing Pharmaceutical Technology Limited | Valproate (vpa) compounds for use in treating spinocerebellar ataxia type 1 (sca1) |
JP7371975B1 (ja) | 2022-09-27 | 2023-10-31 | セルソース株式会社 | 細胞外小胞の製造方法及び細胞外小胞含有組成物 |
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EP1812556A4 (en) * | 2004-10-05 | 2011-02-02 | Univ Georgia | NEURONAL PRECURSORS OF FEEDER-FREE HUMAN EMBRYONIC STEM CELL CULTURE |
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WO2006087233A2 (en) * | 2005-02-21 | 2006-08-24 | Max-Planck-Gesellschaft zur Förderung der Wissenschaft e.V. | Release of extracellular membrane particles carrying the stem cell marker prominin-1 (cd133) from neural progenitors and other epithelial cells |
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JP7075594B2 (ja) | 2015-11-18 | 2022-05-26 | ユニバーシティ オブ ジョージア リサーチ ファウンデーション, インコーポレーテッド | 神経細胞の細胞外小胞 |
WO2017188487A1 (ko) | 2016-04-29 | 2017-11-02 | 삼성전자 주식회사 | 줄기세포 유래의 세포외 소포체 생산 방법 |
MX2019005140A (es) | 2016-11-02 | 2020-01-20 | J Prockop Darwin | Exosomas y usos de los mismos en enfermedades del cerebro. |
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2016
- 2016-11-16 JP JP2018545560A patent/JP7075594B2/ja active Active
- 2016-11-16 KR KR1020187017132A patent/KR20180086440A/ko active Search and Examination
- 2016-11-16 EA EA201891152A patent/EA201891152A1/ru unknown
- 2016-11-16 CA CA3004450A patent/CA3004450A1/en active Pending
- 2016-11-16 US US15/770,881 patent/US11993787B2/en active Active
- 2016-11-16 NZ NZ742327A patent/NZ742327A/en unknown
- 2016-11-16 BR BR112018009891A patent/BR112018009891A2/pt not_active Application Discontinuation
- 2016-11-16 IL IL259470A patent/IL259470B/en unknown
- 2016-11-16 CN CN201680078639.9A patent/CN108697740A/zh active Pending
- 2016-11-16 AU AU2016357303A patent/AU2016357303B2/en active Active
- 2016-11-16 WO PCT/US2016/062245 patent/WO2017087500A1/en active Application Filing
- 2016-11-16 SG SG11201804117XA patent/SG11201804117XA/en unknown
- 2016-11-16 MX MX2018005313A patent/MX2018005313A/es unknown
- 2016-11-16 EP EP16867026.3A patent/EP3377078A4/en active Pending
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2018
- 2018-12-13 HK HK18116022.8A patent/HK1256911A1/zh unknown
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2019
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2021
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- 2021-10-15 JP JP2021169965A patent/JP2022009194A/ja active Pending
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AU2016357303B2 (en) | 2023-11-30 |
HK1256911A1 (zh) | 2019-10-04 |
NZ742327A (en) | 2020-01-31 |
WO2017087500A8 (en) | 2018-05-31 |
US11993787B2 (en) | 2024-05-28 |
EA201891152A1 (ru) | 2018-12-28 |
SG11201804117XA (en) | 2018-06-28 |
EP3377078A4 (en) | 2019-09-04 |
EP3377078A1 (en) | 2018-09-26 |
IL259470A (en) | 2018-07-31 |
BR112018009891A2 (pt) | 2018-12-26 |
US11111475B2 (en) | 2021-09-07 |
JP7075594B2 (ja) | 2022-05-26 |
KR20180086440A (ko) | 2018-07-31 |
AU2016357303A1 (en) | 2018-05-10 |
IL259470B (en) | 2022-08-01 |
WO2017087500A1 (en) | 2017-05-26 |
US20180327714A1 (en) | 2018-11-15 |
US20220356444A1 (en) | 2022-11-10 |
JP2022009194A (ja) | 2022-01-14 |
CA3004450A1 (en) | 2017-05-26 |
JP2018534370A (ja) | 2018-11-22 |
US20190352603A1 (en) | 2019-11-21 |
CN108697740A (zh) | 2018-10-23 |
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