MX2018000512A - Compuestos de indazaol y azaindazol como inhibidores de la cinasa 4 asociada al receptor de interlucina 1 (irak-4). - Google Patents
Compuestos de indazaol y azaindazol como inhibidores de la cinasa 4 asociada al receptor de interlucina 1 (irak-4).Info
- Publication number
- MX2018000512A MX2018000512A MX2018000512A MX2018000512A MX2018000512A MX 2018000512 A MX2018000512 A MX 2018000512A MX 2018000512 A MX2018000512 A MX 2018000512A MX 2018000512 A MX2018000512 A MX 2018000512A MX 2018000512 A MX2018000512 A MX 2018000512A
- Authority
- MX
- Mexico
- Prior art keywords
- irak
- indazole
- inhibitors
- azaindazole compounds
- compounds
- Prior art date
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- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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Abstract
La presente invención provee compuestos de indazol y azaindazol de fórmula (I) o (II), y sales farmacéuticamente aceptables de estos, y su uso para inhibir IRAK-4 y/o para el tratamiento de enfermedades o trastornos inducidos por IRAK-4.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN3630CH2015 | 2015-07-15 | ||
PCT/IB2016/054203 WO2017009798A1 (en) | 2015-07-15 | 2016-07-14 | Indazole and azaindazole compounds as irak-4 inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018000512A true MX2018000512A (es) | 2018-04-13 |
Family
ID=57757043
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018000512A MX2018000512A (es) | 2015-07-15 | 2016-07-14 | Compuestos de indazaol y azaindazol como inhibidores de la cinasa 4 asociada al receptor de interlucina 1 (irak-4). |
Country Status (15)
Country | Link |
---|---|
US (1) | US20180201609A1 (es) |
EP (1) | EP3322698A4 (es) |
JP (1) | JP2018524372A (es) |
KR (1) | KR20180025896A (es) |
CN (1) | CN108026065A (es) |
AU (1) | AU2016293441A1 (es) |
BR (1) | BR112018000624A2 (es) |
CA (1) | CA2992406A1 (es) |
CU (1) | CU20180006A7 (es) |
EA (1) | EA201890307A1 (es) |
HK (1) | HK1249509A1 (es) |
IL (1) | IL256584A (es) |
MX (1) | MX2018000512A (es) |
PH (1) | PH12018500040A1 (es) |
WO (1) | WO2017009798A1 (es) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CU24389B1 (es) | 2014-01-13 | 2019-04-04 | Aurigene Discovery Tech Ltd | Compuestos de heterociclilo bicíclico como inhibidores de irak4 |
JO3705B1 (ar) | 2014-11-26 | 2021-01-31 | Bayer Pharma AG | إندازولات مستبدلة جديدة، عمليات لتحضيرها، مستحضرات دوائية تحتوي عليها واستخدامها في إنتاج أدوية |
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- 2016-07-14 WO PCT/IB2016/054203 patent/WO2017009798A1/en active Application Filing
- 2016-07-14 KR KR1020187001108A patent/KR20180025896A/ko unknown
- 2016-07-14 CN CN201680053232.0A patent/CN108026065A/zh active Pending
- 2016-07-14 JP JP2018501954A patent/JP2018524372A/ja active Pending
- 2016-07-14 US US15/744,448 patent/US20180201609A1/en not_active Abandoned
- 2016-07-14 EA EA201890307A patent/EA201890307A1/ru unknown
- 2016-07-14 EP EP16823968.9A patent/EP3322698A4/en not_active Withdrawn
- 2016-07-14 MX MX2018000512A patent/MX2018000512A/es unknown
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- 2016-07-14 CU CUP2018000006A patent/CU20180006A7/es unknown
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BR112018000624A2 (pt) | 2018-09-18 |
IL256584A (en) | 2018-02-28 |
AU2016293441A1 (en) | 2018-02-01 |
EA201890307A1 (ru) | 2018-10-31 |
CU20180006A7 (es) | 2018-06-05 |
PH12018500040A1 (en) | 2018-07-09 |
JP2018524372A (ja) | 2018-08-30 |
WO2017009798A1 (en) | 2017-01-19 |
CN108026065A (zh) | 2018-05-11 |
US20180201609A1 (en) | 2018-07-19 |
HK1249509A1 (zh) | 2018-11-02 |
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