MX2017013896A - Composicion farmaceutica para administracion oral. - Google Patents

Composicion farmaceutica para administracion oral.

Info

Publication number
MX2017013896A
MX2017013896A MX2017013896A MX2017013896A MX2017013896A MX 2017013896 A MX2017013896 A MX 2017013896A MX 2017013896 A MX2017013896 A MX 2017013896A MX 2017013896 A MX2017013896 A MX 2017013896A MX 2017013896 A MX2017013896 A MX 2017013896A
Authority
MX
Mexico
Prior art keywords
pharmaceutical composition
oral administration
solubility
ethylpyrrolidin
pyrazin
Prior art date
Application number
MX2017013896A
Other languages
English (en)
Inventor
Sakai Toshiro
Nishimura Koji
Suda Yumiko
Kojima Ryo
Oyama Dai
Naiki Kumi
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of MX2017013896A publication Critical patent/MX2017013896A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describe una composición farmacéutica para administración oral, que comprende ácido 1-{5-[(5-{[(2R)-2-etilpirrolidin-1-il]me til}-4-[4-metoxi-3-(trifluorometil)fenil]-1,3-tiazol-2-iI)carbamo il]pirazin-2-il}piperidin-4-carboxílico, que es un compuesto que tiene solubilidad dependiente del pH, o una sal farmacéuticamente aceptable del mismo, y un derivado de celulosa. En la composición farmacéutica para administración oral, se mejoran la solubilidad y la capacidad de absorción del fármaco.
MX2017013896A 2015-04-28 2016-04-27 Composicion farmaceutica para administracion oral. MX2017013896A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015092005 2015-04-28
PCT/JP2016/063151 WO2016175230A1 (ja) 2015-04-28 2016-04-27 経口投与用医薬組成物

Publications (1)

Publication Number Publication Date
MX2017013896A true MX2017013896A (es) 2018-03-15

Family

ID=57198463

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017013896A MX2017013896A (es) 2015-04-28 2016-04-27 Composicion farmaceutica para administracion oral.

Country Status (9)

Country Link
US (1) US10583087B2 (es)
EP (1) EP3290037A4 (es)
JP (1) JP6680297B2 (es)
CN (1) CN107530342A (es)
HK (1) HK1245646A1 (es)
MX (1) MX2017013896A (es)
PH (1) PH12017501831A1 (es)
TW (1) TW201713343A (es)
WO (1) WO2016175230A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019172420A1 (ja) * 2018-03-09 2019-09-12 協和発酵キリン株式会社 医薬組成物
WO2020122244A1 (ja) * 2018-12-14 2020-06-18 富士フイルム株式会社 錠剤及びその製造方法
EP4176902A1 (en) * 2020-07-02 2023-05-10 Artham Therapeutics Inc. Oral pharmaceutical composition and method for producing same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW486370B (en) * 1996-12-25 2002-05-11 Yamanouchi Pharma Co Ltd Rapidly disintegrable pharmaceutical composition
CA2585003C (en) 2004-11-23 2010-08-17 Dong Wha Pharm. Ind. Co., Ltd. An oral preparation having improved bioavailability
US20070178152A1 (en) 2005-11-04 2007-08-02 Shelton Michael C Carboxyalkylcellulose esters for administration of poorly soluble pharmaceutically active agents
TW200927142A (en) * 2007-10-12 2009-07-01 Novartis Ag Compositions comprising sphingosine 1 phosphate (S1P) receptor modulators
DK2593081T3 (da) * 2010-07-15 2014-06-10 Tedec Meiji Farma S A Ferrimannitol-ovalbumin-tabletpræparat
TWI564008B (zh) 2010-09-30 2017-01-01 鹽野義製藥股份有限公司 難溶性藥物之溶解性改善製劑
TWI647227B (zh) 2013-02-28 2019-01-11 日商安斯泰來製藥股份有限公司 ２－醯胺噻唑衍生物或其鹽

Also Published As

Publication number Publication date
TW201713343A (zh) 2017-04-16
EP3290037A1 (en) 2018-03-07
CN107530342A (zh) 2018-01-02
WO2016175230A1 (ja) 2016-11-03
US20180116965A1 (en) 2018-05-03
JP6680297B2 (ja) 2020-04-15
JPWO2016175230A1 (ja) 2018-02-22
PH12017501831A1 (en) 2018-04-23
HK1245646A1 (zh) 2018-08-31
EP3290037A4 (en) 2019-01-23
US10583087B2 (en) 2020-03-10

Similar Documents

Publication Publication Date Title
PH12016501310A1 (en) Pharmaceutical compositions comprising azd9291
PH12017501421A1 (en) Pharmaceutical compositions comprising n-(3,5-dimethoxyphenyl)-n`-(1-methylethyl)-n-[3-(1-methyl-1h-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine
SG194756A1 (en) Modified release of 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-n-5-(4-methyl-1h-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide solubilized using organic acids
EA201792592A1 (ru) Фармацевтические препараты, содержащие тенофовир и эмтрицитабин
JP2015510916A5 (es)
PE20170773A1 (es) Formulaciones farmaceuticas, procesos para la preparacion, y metodos de uso
PH12017501831A1 (en) Pharmaceutical compositions for oral administration
PH12017502252A1 (en) Stable pharmaceutical composition for oral administration
MY182008A (en) Pharmaceutical formulations
MX2020002432A (es) Composicion farmaceutica.
WO2013188465A3 (en) Treating drug addiction and preventing drug relapse
PH12016502285A1 (en) Pharmaceutical composition for oral administration
PH12016502527A1 (en) Stabilized desmopressin
MD20170094A2 (ro) Procedeu de fabricare a amestecurilor de pulbere uscată
TH177974A (th) องค์ประกอบทางเภสัชกรรมสำหรับให้ทางปาก
TN2013000440A1 (en) Modified release of 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-n-5-(4-methyl-1h-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide solubilized using organic acids
RU2764750C3 (ru) Стабильная фармацевтическая композиция для перорального введения
EA201791798A1 (ru) Фармацевтические композиции, включающие n-(3,5-диметоксифенил)-n'-(1-метилэтил)-n-[3-(1-метил-1h-пиразол-4-ил)хиноксалин-6-ил]этан-1,2-диамин
TH167761A (th) องค์ประกอบทางเภสัชกรรมสำหรับให้ทางปาก
UA97982U (uk) Лікарський засіб седативної дії у вигляді таблеток
IN2014MU03782A (es)
TH183323B (th) สูตรที่ให้ทางปากของดีฟีราซิรอกซ์ (deferasirox)