MX2017004943A - Tratamiento de la enfermedad del hígado graso usando antagonistas de receptores de glucocorticoides y de minerarlocorticoides. - Google Patents

Tratamiento de la enfermedad del hígado graso usando antagonistas de receptores de glucocorticoides y de minerarlocorticoides.

Info

Publication number
MX2017004943A
MX2017004943A MX2017004943A MX2017004943A MX2017004943A MX 2017004943 A MX2017004943 A MX 2017004943A MX 2017004943 A MX2017004943 A MX 2017004943A MX 2017004943 A MX2017004943 A MX 2017004943A MX 2017004943 A MX2017004943 A MX 2017004943A
Authority
MX
Mexico
Prior art keywords
liver disease
fatty liver
glucocorticoid
receptor antagonists
disease treatment
Prior art date
Application number
MX2017004943A
Other languages
English (en)
Spanish (es)
Inventor
K Belanoff Joseph
Hazel Hunt
C Meijer Onno
VAN DEN HEUVEL Jose
Original Assignee
Corcept Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corcept Therapeutics Inc filed Critical Corcept Therapeutics Inc
Publication of MX2017004943A publication Critical patent/MX2017004943A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX2017004943A 2014-10-15 2015-10-14 Tratamiento de la enfermedad del hígado graso usando antagonistas de receptores de glucocorticoides y de minerarlocorticoides. MX2017004943A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462064358P 2014-10-15 2014-10-15
US201462092041P 2014-12-15 2014-12-15
PCT/US2015/055487 WO2016061195A1 (en) 2014-10-15 2015-10-14 Fatty liver disease treatment using glucocorticoid and mineralocorticoid receptor antagonists

Publications (1)

Publication Number Publication Date
MX2017004943A true MX2017004943A (es) 2017-07-19

Family

ID=55747256

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017004943A MX2017004943A (es) 2014-10-15 2015-10-14 Tratamiento de la enfermedad del hígado graso usando antagonistas de receptores de glucocorticoides y de minerarlocorticoides.

Country Status (22)

Country Link
US (5) US10238659B2 (enExample)
EP (2) EP4353310A3 (enExample)
JP (1) JP6761410B2 (enExample)
KR (1) KR102435956B1 (enExample)
CN (2) CN111557942B (enExample)
AU (1) AU2015333645B2 (enExample)
BR (1) BR112017007860B1 (enExample)
CA (1) CA2964625C (enExample)
DK (1) DK3206692T3 (enExample)
ES (1) ES2978871T3 (enExample)
FI (1) FI3206692T3 (enExample)
IL (1) IL251729B (enExample)
MX (1) MX2017004943A (enExample)
NZ (1) NZ731060A (enExample)
PH (1) PH12017500710B1 (enExample)
PL (1) PL3206692T3 (enExample)
PT (1) PT3206692T (enExample)
RU (1) RU2718921C2 (enExample)
SG (1) SG11201703024VA (enExample)
UA (1) UA123537C2 (enExample)
WO (1) WO2016061195A1 (enExample)
ZA (1) ZA201702813B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2978871T3 (es) 2014-10-15 2024-09-23 Corcept Therapeutics Inc Tratamiento de la esteatosis hepática usando antagonistas de los receptores de glucocorticoides y de mineralocorticoides
AU2019282047B2 (en) * 2018-06-04 2022-06-02 Corcept Therapeutics Incorporated Pyrimidine cyclohexenyl glucocorticoid receptor modulators
KR20210153056A (ko) 2019-03-18 2021-12-16 리네트 케이. 니만 인슐린 감수성 개선 방법
CN115551836A (zh) * 2020-05-06 2022-12-30 科赛普特治疗公司 嘧啶环己基糖皮质激素受体调节剂的多晶型物
EP4146173A4 (en) * 2020-05-06 2024-05-29 Corcept Therapeutics Incorporated FORMULATIONS OF PYRIMIDINE CYCLOHEXYL GLUCOCORTICOID RECEPTOR MODULATORS
KR102481705B1 (ko) * 2020-08-04 2022-12-27 연세대학교 산학협력단 트리아졸 유도체를 유효성분으로 포함하는 간 섬유증의 예방 또는 치료용 조성물
CA3202353A1 (en) * 2020-12-21 2022-06-30 Jeffrey Mark Dener Method of preparing pyrimidine cyclohexyl glucocorticoid receptor modulators
WO2022235647A1 (en) * 2021-05-05 2022-11-10 Corcept Therapeutics Incorporated Methods for reducing liver fat and for treating fatty liver disorders
WO2025174745A1 (en) * 2024-02-12 2025-08-21 Corcept Therapeutics Incorporated MIRICORILANT TREATMENT FOR FATTY LIVER DISEASES and its EFFECTS on LIVER FAT CONTENT, FATTY ACIDS, ACYLGLYCEROLS, and SECONDARY BILE ACIDS
WO2025255357A1 (en) * 2024-06-06 2025-12-11 Corcept Therapeutics Incorporated Methods for preparing and maintaining livers and portions thereof for liver transplantation

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2153546A (en) 1936-07-29 1939-04-11 Universal Draft Gear Attachmen Hand brake actuating mechanism
US4391904A (en) 1979-12-26 1983-07-05 Syva Company Test strip kits in immunoassays and compositions therein
GB0213745D0 (en) * 2002-06-14 2002-07-24 Univ Edinburgh Enzyme
WO2004009017A2 (en) 2002-07-18 2004-01-29 Bristol-Myers Squibb Company Modulators of the glucocorticoid receptor and method
ATE463479T1 (de) 2005-05-18 2010-04-15 Merck Sharp & Dohme D-homoandrosta-17-yl-carbamat-derivate als selektive glucocorticoid-rezeptor-liganden
WO2007022518A2 (en) 2005-08-19 2007-02-22 Amylin Pharmaceuticals, Inc. New uses of glucoregulatory proteins
WO2007035759A1 (en) * 2005-09-19 2007-03-29 Johnson & Johnson Pharmaceutical Research & Development L.L.C. Modulation of glucocorticoid receptor expression
GB0601092D0 (en) * 2006-01-19 2006-03-01 Daniolabs Ltd The Prevention Of Systemic Side-Effects Of Glucocorticoids
PT2032134E (pt) 2006-05-09 2015-10-07 Genzyme Corp Métodos de tratamento da doença do fígado gorduroso
US9623021B2 (en) 2007-01-22 2017-04-18 Gtx, Inc. Nuclear receptor binding agents
MX2009011062A (es) 2007-04-13 2009-10-29 Schering Corp Derivados de pirimidindiona y sus metodos de uso.
US8003689B2 (en) 2008-06-20 2011-08-23 Gtx, Inc. Metabolites of selective androgen receptor modulators and methods of use thereof
JP5511942B2 (ja) 2009-04-03 2014-06-04 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 組成物及びその使用
SG193509A1 (en) 2011-03-18 2013-10-30 Corcept Therapeutics Inc Pyrimidine cyclohexyl glucocorticoid receptor modulators
ES2978871T3 (es) 2014-10-15 2024-09-23 Corcept Therapeutics Inc Tratamiento de la esteatosis hepática usando antagonistas de los receptores de glucocorticoides y de mineralocorticoides

Also Published As

Publication number Publication date
EP3206692A1 (en) 2017-08-23
JP6761410B2 (ja) 2020-09-23
US20160106749A1 (en) 2016-04-21
CN107106562B (zh) 2020-08-18
US11590135B2 (en) 2023-02-28
CA2964625C (en) 2023-03-07
WO2016061195A1 (en) 2016-04-21
IL251729A0 (en) 2017-06-29
ZA201702813B (en) 2019-05-29
BR112017007860A2 (pt) 2018-01-16
EP3206692A4 (en) 2018-05-30
AU2015333645A1 (en) 2017-05-04
PH12017500710B1 (en) 2024-01-17
KR102435956B1 (ko) 2022-08-23
US10881660B2 (en) 2021-01-05
US20230218621A1 (en) 2023-07-13
DK3206692T3 (da) 2024-04-29
CN111557942B (zh) 2023-10-03
NZ731060A (en) 2023-07-28
PH12017500710A1 (en) 2017-10-09
BR112017007860B1 (pt) 2023-03-07
US20210085682A1 (en) 2021-03-25
EP4353310A2 (en) 2024-04-17
FI3206692T3 (fi) 2024-05-06
AU2015333645B2 (en) 2020-01-30
RU2718921C2 (ru) 2020-04-15
CN111557942A (zh) 2020-08-21
PL3206692T3 (pl) 2024-07-22
UA123537C2 (uk) 2021-04-21
US12226417B2 (en) 2025-02-18
ES2978871T3 (es) 2024-09-23
JP2017531013A (ja) 2017-10-19
IL251729B (en) 2020-03-31
KR20170066646A (ko) 2017-06-14
CA2964625A1 (en) 2016-04-21
RU2017114596A (ru) 2018-11-15
EP3206692B1 (en) 2024-04-03
PT3206692T (pt) 2024-04-30
CN107106562A (zh) 2017-08-29
SG11201703024VA (en) 2017-05-30
EP4353310A3 (en) 2024-06-19
US20190151318A1 (en) 2019-05-23
US20250221995A1 (en) 2025-07-10
US10238659B2 (en) 2019-03-26
RU2017114596A3 (enExample) 2019-05-08

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