MX2017001176A - Terapia de combinacion. - Google Patents

Terapia de combinacion.

Info

Publication number
MX2017001176A
MX2017001176A MX2017001176A MX2017001176A MX2017001176A MX 2017001176 A MX2017001176 A MX 2017001176A MX 2017001176 A MX2017001176 A MX 2017001176A MX 2017001176 A MX2017001176 A MX 2017001176A MX 2017001176 A MX2017001176 A MX 2017001176A
Authority
MX
Mexico
Prior art keywords
combination therapy
combination
inhibitor
inc280
panitumumab
Prior art date
Application number
MX2017001176A
Other languages
English (en)
Inventor
Huang Xizhong
Hao Huaixiang
Manenti Luigi
Tam Angela
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2017001176A publication Critical patent/MX2017001176A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Abstract

La presente descripción se refiere a los productos farmacéuticos que comprenden una combinación de (i) un inhibidor de MET que es INC28O o una sal o hidrato farmacéuticamente aceptable del mismo y (ii) un inhibidor de EGFR que es un anticuerpo monoclonal tal como cetuximab o panitumumab, que son conjuntamente activo en el tratamiento de enfermedades proliferativas, formulaciones farmacéuticas correspondientes, usos, métodos, procesos, los paquetes comerciales y formas de realización relacionadas.
MX2017001176A 2014-07-25 2015-07-23 Terapia de combinacion. MX2017001176A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/CN2014/083014 WO2016011658A1 (en) 2014-07-25 2014-07-25 Combination therapy
PCT/CN2015/084886 WO2016011956A1 (en) 2014-07-25 2015-07-23 Combination therapy

Publications (1)

Publication Number Publication Date
MX2017001176A true MX2017001176A (es) 2017-05-01

Family

ID=55162455

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017001176A MX2017001176A (es) 2014-07-25 2015-07-23 Terapia de combinacion.

Country Status (11)

Country Link
US (2) US20170224692A1 (es)
EP (1) EP3171876A4 (es)
JP (2) JP2017521468A (es)
KR (1) KR20170036010A (es)
CN (1) CN106794180A (es)
AU (3) AU2015291994A1 (es)
BR (1) BR112017001165A2 (es)
CA (1) CA2954831A1 (es)
MX (1) MX2017001176A (es)
RU (1) RU2017105817A (es)
WO (2) WO2016011658A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2834246B1 (en) 2012-04-03 2021-07-28 Novartis AG Combination products with tyrosine kinase inhibitors and their use
US20190360029A1 (en) * 2017-01-20 2019-11-28 The Jackson Laboratory A method of targeting patient-specific oncogenes in extrachromosomal dna to treat glioblastoma
US20200043597A1 (en) * 2018-08-03 2020-02-06 Catalight Foundation Methods for applying advanced multi-step analytics to generate treatment plan data and devices thereof
WO2022007752A1 (zh) * 2020-07-06 2022-01-13 苏州晶云药物科技股份有限公司 苯甲酰胺类化合物及其二盐酸盐的新晶型及其制备方法

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Also Published As

Publication number Publication date
EP3171876A1 (en) 2017-05-31
AU2015291994A1 (en) 2017-02-02
JP2017521468A (ja) 2017-08-03
AU2018256669A1 (en) 2018-11-22
US20200101077A1 (en) 2020-04-02
RU2017105817A (ru) 2018-08-27
BR112017001165A2 (pt) 2017-11-14
CA2954831A1 (en) 2016-01-28
WO2016011956A1 (en) 2016-01-28
RU2017105817A3 (es) 2019-03-12
KR20170036010A (ko) 2017-03-31
US20170224692A1 (en) 2017-08-10
JP2020143068A (ja) 2020-09-10
CN106794180A (zh) 2017-05-31
EP3171876A4 (en) 2018-03-28
AU2020204027A1 (en) 2020-07-09
WO2016011658A1 (en) 2016-01-28

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