MX2016015363A - Terapias de combinacion para el tratamiento de cancer. - Google Patents

Terapias de combinacion para el tratamiento de cancer.

Info

Publication number
MX2016015363A
MX2016015363A MX2016015363A MX2016015363A MX2016015363A MX 2016015363 A MX2016015363 A MX 2016015363A MX 2016015363 A MX2016015363 A MX 2016015363A MX 2016015363 A MX2016015363 A MX 2016015363A MX 2016015363 A MX2016015363 A MX 2016015363A
Authority
MX
Mexico
Prior art keywords
cancer
treatment
combination therapies
combination
antagonist
Prior art date
Application number
MX2016015363A
Other languages
English (en)
Inventor
Bao Xingfeng
ALBU Diana
WOODALL-JAPPE Mary
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of MX2016015363A publication Critical patent/MX2016015363A/es

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Abstract

La presente invención proporciona métodos y composiciones para tratar cáncer al administrar un antagonista de EP4 en combinación con terapia de radiación, terapia con anticuerpo y/o quimioterapia con anti-metabolitos.
MX2016015363A 2014-05-23 2015-05-21 Terapias de combinacion para el tratamiento de cancer. MX2016015363A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462002366P 2014-05-23 2014-05-23
US201562150004P 2015-04-20 2015-04-20
PCT/US2015/031931 WO2015179615A1 (en) 2014-05-23 2015-05-21 Combination therapies for the treatment of cancer

Publications (1)

Publication Number Publication Date
MX2016015363A true MX2016015363A (es) 2017-05-30

Family

ID=53277114

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016015363A MX2016015363A (es) 2014-05-23 2015-05-21 Terapias de combinacion para el tratamiento de cancer.

Country Status (13)

Country Link
US (2) US20170182003A1 (es)
EP (1) EP3134085A1 (es)
JP (2) JP6787792B2 (es)
KR (1) KR102535283B1 (es)
CN (2) CN106572993B (es)
AU (1) AU2015264102C1 (es)
CA (1) CA2949961C (es)
IL (1) IL249065A0 (es)
MA (1) MA39906A (es)
MX (1) MX2016015363A (es)
RU (1) RU2708374C2 (es)
SG (1) SG11201609770TA (es)
WO (1) WO2015179615A1 (es)

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Also Published As

Publication number Publication date
IL249065A0 (en) 2017-01-31
JP2017516775A (ja) 2017-06-22
US11707448B2 (en) 2023-07-25
SG11201609770TA (en) 2016-12-29
JP2020128432A (ja) 2020-08-27
US20170182003A1 (en) 2017-06-29
KR20170017933A (ko) 2017-02-15
WO2015179615A1 (en) 2015-11-26
CA2949961C (en) 2023-09-19
AU2015264102A1 (en) 2016-12-08
EP3134085A1 (en) 2017-03-01
CN106572993A (zh) 2017-04-19
CN106572993B (zh) 2019-07-16
MA39906A (fr) 2017-03-01
RU2708374C2 (ru) 2019-12-06
AU2015264102B2 (en) 2020-02-13
AU2015264102C1 (en) 2020-10-08
JP6787792B2 (ja) 2020-11-18
US20220071959A1 (en) 2022-03-10
RU2016150650A (ru) 2018-06-26
CN110354266A (zh) 2019-10-22
CA2949961A1 (en) 2015-11-26
KR102535283B1 (ko) 2023-05-22
RU2016150650A3 (es) 2018-12-25

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