MX2016013255A - Metodos y composiciones para detectar proteinas mal plegadas. - Google Patents
Metodos y composiciones para detectar proteinas mal plegadas.Info
- Publication number
- MX2016013255A MX2016013255A MX2016013255A MX2016013255A MX2016013255A MX 2016013255 A MX2016013255 A MX 2016013255A MX 2016013255 A MX2016013255 A MX 2016013255A MX 2016013255 A MX2016013255 A MX 2016013255A MX 2016013255 A MX2016013255 A MX 2016013255A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- methods
- misfolded proteins
- detecting misfolded
- pregnant woman
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6827—Total protein determination, e.g. albumin in urine
- G01N33/6839—Total protein determination, e.g. albumin in urine involving dyes, e.g. Coomassie blue, bromcresol green
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B69/00—Dyes not provided for by a single group of this subclass
- C09B69/10—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
- C09B69/106—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds containing an azo dye
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Varios aspectos y modalidades de la presente descripción están dirigidos hacia métodos y composiciones (por ejemplo, kits) para la identificación de sujetos con proteínas mal plegadas en su orina; por ejemplo, se proveen métodos y composiciones para determinar que una muestra de orina de una mujer embarazada contiene o no contiene proteínas mal plegadas; en algunas modalidades, la presencia de proteínas mal plegadas en una muestra de orina de una mujer embarazada, es una indicación de preeclampsia.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461978158P | 2014-04-10 | 2014-04-10 | |
PCT/US2015/025432 WO2015157704A2 (en) | 2014-04-10 | 2015-04-10 | Methods and compositions for detecting misfolded proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016013255A true MX2016013255A (es) | 2017-05-03 |
Family
ID=54264908
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016013255A MX2016013255A (es) | 2014-04-10 | 2015-04-10 | Metodos y composiciones para detectar proteinas mal plegadas. |
MX2021006791A MX2021006791A (es) | 2014-04-10 | 2016-10-07 | Metodos y composiciones para detectar proteinas mal plegadas. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021006791A MX2021006791A (es) | 2014-04-10 | 2016-10-07 | Metodos y composiciones para detectar proteinas mal plegadas. |
Country Status (11)
Country | Link |
---|---|
US (3) | US10324094B2 (es) |
EP (2) | EP3745127B1 (es) |
JP (1) | JP6697394B2 (es) |
CN (2) | CN116027043A (es) |
AU (3) | AU2015243171B2 (es) |
CA (2) | CA2945058C (es) |
DK (1) | DK3129779T3 (es) |
ES (1) | ES2817417T3 (es) |
MX (2) | MX2016013255A (es) |
WO (1) | WO2015157704A2 (es) |
ZA (1) | ZA201606987B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105021821B (zh) | 2008-10-31 | 2018-05-11 | 耶鲁大学 | 先兆子痫检测和治疗的方法和组合物 |
CN116027043A (zh) | 2014-04-10 | 2023-04-28 | 耶鲁大学 | 检测错误折叠蛋白的方法和组合物 |
EP3322985B1 (en) | 2015-07-15 | 2021-10-13 | Gestvision, Inc. | Device for detecting misfolded proteins and methods of use thereof |
US11344121B2 (en) | 2016-04-14 | 2022-05-31 | The Texas A&M University System | Methods of predicting preeclampsia using biomarkers |
US10345244B2 (en) * | 2016-06-03 | 2019-07-09 | International Business Machines Corporation | Diagnostic test device with patterned material spots |
US10335045B2 (en) | 2016-06-24 | 2019-07-02 | Universita Degli Studi Di Trento | Self-adaptive matrix completion for heart rate estimation from face videos under realistic conditions |
US10269107B2 (en) * | 2017-02-23 | 2019-04-23 | Global Neighbor Inc | Selective plant detection and treatment using green luminance photometric machine vision scan with real time chromaticity operations and image parameter floors for low processing load |
AU2018345841A1 (en) | 2017-10-06 | 2020-05-21 | The Research Foundation For The State University For The State Of New York | Selective optical aqueous and non-aqueous detection of free sulfites |
WO2019128506A1 (zh) * | 2017-12-28 | 2019-07-04 | 浙江数问生物技术有限公司 | 一种检测错误折叠蛋白质的装置、试剂盒和方法 |
US11255844B2 (en) * | 2018-03-06 | 2022-02-22 | Fresenius Medical Care Holdings, Inc. | Peritoneal dialysis systems and related methods |
CN109659011A (zh) * | 2018-12-29 | 2019-04-19 | 杭州脉流科技有限公司 | 利用移动设备采集处理十二导联ecg图像的方法以及移动设备和计算机可读存储介质 |
US20240003909A1 (en) * | 2020-11-21 | 2024-01-04 | Xingmin Li | Apparatus and method for detecting misfolded protein in biological sample |
WO2023222136A1 (zh) * | 2022-05-20 | 2023-11-23 | 数问生物技术(宣城)有限公司 | 用于检测生物样本中的错误折叠蛋白质的装置和系统 |
CN117236201B (zh) * | 2023-11-16 | 2024-02-23 | 南京信息工程大学 | 一种基于Diffusion和ViT的降尺度方法 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US234610A (en) * | 1880-11-16 | Robert o | ||
US4444879A (en) | 1981-01-29 | 1984-04-24 | Science Research Center, Inc. | Immunoassay with article having support film and immunological counterpart of analyte |
WO1992017769A1 (en) * | 1991-03-28 | 1992-10-15 | Micro Research Inc. | Controlled-release solid phase assay device including encapsulated reagents for detecting chemical substances |
US5998216A (en) | 1996-10-01 | 1999-12-07 | Beth Israel Deaconess Medical Center | Stabilizing formulation for preserving the integrity of proteins present in a body fluid sampled ex-vivo for evaluation as a specimen |
EP0951298A1 (en) | 1996-12-23 | 1999-10-27 | Cambridge University Technical Services Limited | Diagnosis and treatment of pathological pregnancies |
US6444435B1 (en) * | 2000-11-30 | 2002-09-03 | Serim Research Corporation | Test strip for determining dialysate composition |
US7355044B2 (en) | 2001-10-25 | 2008-04-08 | Agfa-Gevaert N.V. | Self-assembling dyes |
EA200500232A1 (ru) | 2002-07-19 | 2005-12-29 | Бет Изрейэл Диконисс Медикал Сентер | Способы диагностики и лечения преэклампсии или эклампсии |
WO2004024090A2 (en) | 2002-09-12 | 2004-03-25 | The Regents Of The University Of California | Immunogens and corresponding antibodies specific for high molecular weight aggregation intermediates common to amyloids formed from proteins of differing sequence |
CN101299962A (zh) | 2004-12-15 | 2008-11-05 | 貝丝以色列女执事医疗中心 | 可用于诊断和治疗妊娠并发症的核酸和多肽 |
ES2371084T3 (es) | 2004-12-21 | 2011-12-27 | Yale University | Diagnóstico de la preeclampsia. |
EP1733762A1 (en) * | 2005-05-25 | 2006-12-20 | 3M Espe AG | Dental composition for detection of carious tissue, detection method |
US8263342B2 (en) | 2005-10-27 | 2012-09-11 | Yale University | Urinary proteomic biomarker patterns in preeclampsia |
CA2703254A1 (en) * | 2007-10-18 | 2009-04-23 | Jacob Mullerad | A diagnostic device for identifying rupture of membrane during pregnancy |
US20110065139A1 (en) * | 2007-11-27 | 2011-03-17 | Jacob Mullerad | diagnostic device for identifying rupture of membrane during pregnancy |
CN105021821B (zh) * | 2008-10-31 | 2018-05-11 | 耶鲁大学 | 先兆子痫检测和治疗的方法和组合物 |
CN103012599B (zh) | 2012-11-28 | 2015-04-29 | 龙岩九健生物芯片技术研究所 | 一种调节硝酸纤维素硝化取代度的方法 |
CN116027043A (zh) | 2014-04-10 | 2023-04-28 | 耶鲁大学 | 检测错误折叠蛋白的方法和组合物 |
-
2015
- 2015-04-10 CN CN202210738173.8A patent/CN116027043A/zh active Pending
- 2015-04-10 EP EP20168843.9A patent/EP3745127B1/en active Active
- 2015-04-10 JP JP2016561743A patent/JP6697394B2/ja active Active
- 2015-04-10 DK DK15776737.7T patent/DK3129779T3/da active
- 2015-04-10 CA CA2945058A patent/CA2945058C/en active Active
- 2015-04-10 US US14/683,908 patent/US10324094B2/en active Active
- 2015-04-10 CN CN201580031385.0A patent/CN106461644B/zh active Active
- 2015-04-10 CA CA3157573A patent/CA3157573A1/en active Pending
- 2015-04-10 AU AU2015243171A patent/AU2015243171B2/en active Active
- 2015-04-10 EP EP15776737.7A patent/EP3129779B1/en active Active
- 2015-04-10 WO PCT/US2015/025432 patent/WO2015157704A2/en active Application Filing
- 2015-04-10 MX MX2016013255A patent/MX2016013255A/es unknown
- 2015-04-10 ES ES15776737T patent/ES2817417T3/es active Active
-
2016
- 2016-10-07 MX MX2021006791A patent/MX2021006791A/es unknown
- 2016-10-11 ZA ZA2016/06987A patent/ZA201606987B/en unknown
-
2019
- 2019-05-08 US US16/406,942 patent/US11079392B2/en active Active
-
2020
- 2020-10-02 AU AU2020244572A patent/AU2020244572B2/en active Active
-
2021
- 2021-06-29 US US17/361,967 patent/US11953505B2/en active Active
-
2022
- 2022-12-23 AU AU2022291625A patent/AU2022291625B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
AU2022291625B2 (en) | 2024-09-12 |
ES2817417T3 (es) | 2021-04-07 |
MX2021006791A (es) | 2021-07-15 |
US11079392B2 (en) | 2021-08-03 |
AU2020244572A1 (en) | 2020-11-05 |
US20190353662A1 (en) | 2019-11-21 |
JP2017518483A (ja) | 2017-07-06 |
WO2015157704A3 (en) | 2016-04-28 |
CA2945058A1 (en) | 2015-10-15 |
WO2015157704A2 (en) | 2015-10-15 |
CN106461644B (zh) | 2022-05-13 |
EP3745127A1 (en) | 2020-12-02 |
US20150293115A1 (en) | 2015-10-15 |
CA3157573A1 (en) | 2015-10-15 |
US20220043001A1 (en) | 2022-02-10 |
AU2015243171A1 (en) | 2016-10-27 |
JP6697394B2 (ja) | 2020-05-20 |
ZA201606987B (en) | 2020-01-29 |
EP3129779B1 (en) | 2020-06-03 |
CN116027043A (zh) | 2023-04-28 |
US11953505B2 (en) | 2024-04-09 |
DK3129779T3 (da) | 2020-09-07 |
AU2015243171B2 (en) | 2020-10-15 |
CN106461644A (zh) | 2017-02-22 |
AU2020244572B2 (en) | 2022-12-15 |
CA2945058C (en) | 2022-07-12 |
EP3129779A2 (en) | 2017-02-15 |
AU2022291625A1 (en) | 2023-02-16 |
US10324094B2 (en) | 2019-06-18 |
EP3745127B1 (en) | 2024-08-28 |
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