CO2017007275A2 - Métodos para diagnosticar enfermedad valvular crónica - Google Patents

Métodos para diagnosticar enfermedad valvular crónica

Info

Publication number
CO2017007275A2
CO2017007275A2 CONC2017/0007275A CO2017007275A CO2017007275A2 CO 2017007275 A2 CO2017007275 A2 CO 2017007275A2 CO 2017007275 A CO2017007275 A CO 2017007275A CO 2017007275 A2 CO2017007275 A2 CO 2017007275A2
Authority
CO
Colombia
Prior art keywords
sample
animal
valve disease
mirna
amount
Prior art date
Application number
CONC2017/0007275A
Other languages
English (en)
Inventor
Qinghong Li
Original Assignee
Nestec Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestec Sa filed Critical Nestec Sa
Publication of CO2017007275A2 publication Critical patent/CO2017007275A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La invención proporciona métodos para diagnosticar enfermedad valvular crónica en un animal. Los métodos comprenden obtener una muestra del animal; analizar una cantidad de un microARN (miARN) asociado con enfermedad valvular crónica en la muestra; comparar la cantidad del miARN identificado en la muestra con una cantidad correspondiente del miARN presente en una muestra de uno o más animales de control comparables que no padecen de enfermedad valvular crónica; y diagnosticar enfermedad valvular crónica en el animal si la cantidad del miARN encontrado en la muestra del animal se expresa diferencialmente en la muestra del animal de control.
CONC2017/0007275A 2015-02-17 2017-07-21 Métodos para diagnosticar enfermedad valvular crónica CO2017007275A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562117189P 2015-02-17 2015-02-17
PCT/IB2016/050583 WO2016132244A1 (en) 2015-02-17 2016-02-04 Methods for diagnosing chronic valvular disease

Publications (1)

Publication Number Publication Date
CO2017007275A2 true CO2017007275A2 (es) 2017-09-29

Family

ID=55411713

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2017/0007275A CO2017007275A2 (es) 2015-02-17 2017-07-21 Métodos para diagnosticar enfermedad valvular crónica

Country Status (13)

Country Link
US (1) US20160237495A1 (es)
EP (1) EP3259368B1 (es)
JP (1) JP6760948B2 (es)
CN (1) CN107208161B (es)
AU (1) AU2016221451B2 (es)
CA (1) CA2971993C (es)
CL (1) CL2017001813A1 (es)
CO (1) CO2017007275A2 (es)
ES (1) ES2754384T3 (es)
MX (1) MX2017010352A (es)
NZ (1) NZ732593A (es)
RU (1) RU2711967C2 (es)
WO (1) WO2016132244A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7389807B2 (ja) 2018-12-27 2023-11-30 ソシエテ・デ・プロデュイ・ネスレ・エス・アー イヌ科動物における変性性僧帽弁疾患を診断及び治療するための組成物及び方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2094869B1 (de) * 2006-10-09 2012-07-25 Julius-Maximilians-Universität Würzburg Microrna (mirna) zur diagnose und therapie von herzerkrankungen
EP2179060B1 (en) * 2007-07-18 2013-11-27 The Regents of the University of Colorado Differential expression of micrornas in nonfailing versus failing human hearts

Also Published As

Publication number Publication date
ES2754384T3 (es) 2020-04-17
CA2971993C (en) 2023-04-11
NZ732593A (en) 2022-12-23
CL2017001813A1 (es) 2018-04-06
BR112017014201A2 (pt) 2018-01-02
MX2017010352A (es) 2018-01-23
RU2017132274A3 (es) 2019-08-07
AU2016221451B2 (en) 2021-10-14
JP2018504912A (ja) 2018-02-22
EP3259368B1 (en) 2019-09-25
WO2016132244A1 (en) 2016-08-25
EP3259368A1 (en) 2017-12-27
RU2017132274A (ru) 2019-03-21
RU2711967C2 (ru) 2020-01-23
US20160237495A1 (en) 2016-08-18
JP6760948B2 (ja) 2020-09-23
CN107208161A (zh) 2017-09-26
CN107208161B (zh) 2022-01-07
AU2016221451A1 (en) 2017-06-29
CA2971993A1 (en) 2016-08-25

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